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The handle http://hdl.handle.net/1887/57509 holds various files of this Leiden University dissertation

Author: Datema, Mirjam

Title: Peripheral nerve damage : diagnosis and prediction of recovery

Date: 2017-11-29

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Peripheral nerve damage

Diagnosis and Prediction of Recovery

Mirjam Datema

Bruekelen.indd 1 31-10-2017 08:47:33

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The research described in this thesis was performed at the Department of Neurology and Clinical Neurophysiology of the Leiden University Medical Centre, Leiden, the Netherlands.

The printing of this thesis was financially supported by Chipsoft

Nederlandse Vereniging voor Klinische Neurofysiologie

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Peripheral nerve damage

Diagnosis and Prediction of Recovery

Proefschrift

Ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,

volgens besluit van het College voor Promoties te verdedigen op woensdag 29 november 2017

klokke 16:15 uur

door

Mirjam Datema

geboren te Delft in 1985

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Promotores Prof. dr. J.G. van Dijk Prof. dr. M.J.A. Malessy

Copromotor Dr. M.R. Tannemaat

Leden promotiecommissie Prof. dr. R.A.C. Roos

Dr. E. Hoitsma (Alrijne Ziekenhuis, Leiden)

Prof. dr. L.H. Visser (Universiteit voor Humanistiek, Utrecht; Elisabeth-TweeSteden Ziekenhuis, Tilburg)

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CONTENTS

Chapter 1. General introduction and scope of this thesis 7 PART I DIAGNOSIS

Chapter 2. The diagnostic value of water immersion skin wrinkling and Neuropads

in small fiber neuropathy 23

Chapter 3. Tinel’s sign has no diagnostic value for nerve entrapment of neuropathy

in the legs 39

Chapter 4. Decompressive surgery for diabetic neuropathy: Waiting for

incontrovertible proof 53

PART II PREDICTION OF RECOVERY

Chapter 5. Anterior subcutaneous transposition for persistent ulnar neuropathy

after neurolysis 65

Chapter 6. Outcome of carpal tunnel release and the relation with depression 81 Chapter 7. Sensation recovers less in the old than in the young patient after carpal

tunnel release 97

Chapter 8. Summary and Discussion & Future perspectives 115

Nederlandse samenvatting 129

List of abbreviations 136

Co-author affiliations 138

Curriculum vitae 139

List of publications 140

Dankwoord 141

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