The handle http://hdl.handle.net/1887/81992 holds various files of this Leiden University
dissertation.
Author: Hoekman, E.J.
Title: Ovarian and fertility preservation prior to gonadotoxic treatment : efficacy and
safety studies
Ovarian and fertility preservation
prior to gonadotoxic treatment
Efficacy and safety studies
The studies were financially supported by a grant from A Sister’s hope, The Netherlands, DSW health insurance Schiedam and IVF laboratory Reinier de Graaf hospital Voorburg, The Netherlands.
Ovarian and fertility preservation
prior to gonadotoxic treatment
Efficacy and safety studies
Proefschrift Ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker
volgens besluit van het College voor Promoties te verdedigen op 19 December 2019
klokke 15:00 uur
door
Ellen Josephine Hoekman geboren te Enschede
Aut numquam tentes, aut perfice.
Ovidius 43 v.C. - 17 n.C.
Contents
Chapter 1 General introduction
Part A Fertility preservation prior to chemotherapy: Ovarian tissue cryopreservation
Chapter 2 Ovarian tissue cryopreservation: low usage rates and high live-birth rate after transplantation
Chapter 3 Searching for metastases in ovarian tissue prior to autotransplantation: a tailor-made approach
Part B Fertility preservation prior to radiotherapy: Ovarian transposition Chapter 4 Ovarian survival after pelvic radiation: transposition until the age
of 35
Chapter 5 Ovarian function after ovarian transposition and additional pelvic radiotherapy: a systematic review
Part C Fertility preservation prior to chemotherapy or radiotherapy: Introducing vitrification
Chapter 6 Learning aspects in implementing a vitrification program using mouse blastocysts
Chapter 7 General discussion and future perspectives Chapter 8 Summary
Nederlandse samenvatting Chapter 9 Abbreviations
