Cover Page
The handle
http://hdl.handle.net/1887/67117
holds various files of this Leiden University
dissertation.
Author: Haak, L. van den
Implementing new surgical instruments
in minimally invasive surgery
This PhD thesis was partly funded by the European Regional Development Fund. Financial support for printing of this thesis was kindly provided by the department of Gynecology of the Leiden University Medical Center, Raad van Bestuur Haaglanden Medisch Centrum, The Nederlandse Vereniging voor Endoscopische Chirurgie (NVEC), Erbe, Chipsoft and the Walaeus bibliotheek.
Implementing new surgical instruments
in minimally invasive surgery
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op donderdag 15 november 2018
klokke 13.45
door
Lukas van den Haak
geboren te DongenPromotor prof. dr. F.W. Jansen Copromotoren dr. T.E. Nieboer
(Radboud Universitair Medisch Centrum, Nijmegen) dr. J.P. Rhemrev
(Haaglanden Medisch Centrum, Den Haag) Leden promotiecommissie prof. dr. D. Oepkes
prof. dr. drs. M.P. Schijven
(Academisch Medisch Centrum, Amsterdam) prof. dr. J.J. van den Dobbelsteen
Table of contents
Chapter 1 General Introduction 9
Chapter 2 A new approach to simplify surgical colpotomy in laparoscopic hysterectomy
17
Chapter 3 Efficacy and Safety of Uterine Manipulators in Laparoscopic Surgery: a Review
33
Chapter 4 Human cadavers to evaluate prototypes of minimally invasive surgical instruments: a feasibility study.
53
Chapter 5 Assessing basic ‘Physiology’ of the Morcellation Process and Tissue Spread: A Time Action analysis
65
Chapter 6 Power morcellator features affecting tissue spill in gynecological Laparoscopy: an in vitro study
79
Chapter 7 A laparoscopic morcellator redesign to constrain tissue using integrated gripping teeth
91
Chapter 8 Incidence and groups at risk for unexpected uterine leiomyosarcoma: A Dutch nationwide cohort study
121
Chapter 9 Disseminated leiomyoma cells can be identified following conventional myomectomy
135
Chapter 10 Towards spill-free in-bag morcellation: a health failure mode and effects analysis
147
Chapter 11 Discussion and Future Perspectives 161
Chapter 12 Summary / Samenvatting 179
Chapter 13 Authors’ affiliations 187
List of publications 188
Curriculum Vitae 191
