University of Groningen Evidence-b(i)ased psychiatry de Vries, Ymkje Anna

Evidence-b(i)ased psychiatry

de Vries, Ymkje Anna

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Publication date: 2018

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de Vries, Y. A. (2018). Evidence-b(i)ased psychiatry. University of Groningen.

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6Q` S.- i?2 T`BK`v Qmi+QK2 7Q` KQbi i`BHb rb i?2 MmK#2` Q7 TMB+ ii+Fb Qp2`  R Ĝ j r22F iBK2 7`K2- /B+?QiQKBx2/ BMiQ y U`2KBii2/V Q` ≥ R UMQi `2KBii2/Vc 9 i`BHb- ?Qr2p2`-mb2/ i?2 +?M;2 BM MmK#2` Q7 TMB+ ii+Fb b  T`BK`v Qmi+QK2 K2bm`2X h?2`27Q`2-r2 HbQ 2ti`+i2/ /i QM i?2 T`QTQ`iBQM Q7 T`iB+BTMib i?i h?2`27Q`2-r2`2 7`22 Q7 TMB+ ii+Fb i 2M/TQBMi U`2KBbbBQM `i2VX 6m`i?2`KQ`2- #b2HBM2 b+Q`2b r2`2 `2TQ`i2/ b i?2 MmK#2` Q7 TMB+ ii+Fb BM i?2 R- k Q` j r22Fb #27Q`2 #b2HBM2c r2 +QMp2`i2/ HH b+Q`2b iQ  k@r22F iBK2 7`K2X

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Rjy

PmiHB2`b M/ KBbbBM; /i

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q2 r2`2 #H2 iQ Q#iBM /i QM i?2 K2M +?M;2 b+Q`2 M/ Bib a1fa. UQ` i?2 `2KBbbBQM `i2 7Q` S. i`BHbV 7Q` 9e Qmi Q7 8e i`BHbX 6Q` 9y i`BHb- i?2 6. `2pB2r T`QpB/2/ +QKTH2i2 /ic 7Q` k i`BHb- r2 Q#iBM2/ /i QM i?2 a1fa. 7`QK i?2 :HtQaKBi?EHBM2 i`BH `2;Bbi`vc M/ 7Q` 9 i`BHb- r2 Q#iBM2/ /i QM i?2 a1fa. Uj i`BHbV Q` i?2 `2KBbbBQM `i2 UR i`BHV 7`QK i?2 Ki+?BM; Tm#HBb?2/ DQm`MH `iB+H2b- 7i2` p2`B7vBM; i?i K2M #b2HBM2 M/ +?M;2 b+Q`2b Ki+?2/ i?Qb2 BM i?2 +Q``2bTQM/BM; 6. `2pB2rX

6Q` Ry Qmi Q7 8e i`BHb- MQi HH `2[mB`2/ /i +QmH/ #2 Q#iBM2/ 7`QK Mv bQm`+2X AM7Q`@ KiBQM QM i?2 a1fa. Q7 i?2 +?M;2 b+Q`2 rb KBbbBM; 7Q` R Sha. M/ e P*. r?BH2 BM7Q`KiBQM QM i?2 `2KBbbBQM `i2 rb KBbbBM; 7Q` j S. i`BHbX 6Q` HH Ry i`BHb-?Qr2p2`- BM7Q`KiBQM QM i?2 K2M +?M;2 b+Q`2 rb pBH#H2X 6Q` Sha. M/ P*.- i?2 +?M;2 b+Q`2 Bib2H7 rb bi`QM;Hv +Q``2Hi2/ rBi? Bib a. BM ;`QmTb rBi?Qmi KBbbBM; /ic r2 i?2`27Q`2 BKTmi2/ i?2b2 KBbbBM; a.b #b2/ mTQM i?2 +?M;2 b+Q`2- ;`QmT K2K#2`b?BT M/ i?2B` BMi2`+iBQMX 6Q` S.- 2M/TQBMi b+Q`2 rb bi`QM;Hv +Q``2Hi2/ rBi? i?2 `2KBbbBQM `i2 M/ r2 i?2`27Q`2 BKTmi2/ KBbbBM; `2KBbbBQM `i2b #b2/ mTQM i?2 2M/TQBMi b+Q`2-;`QmT K2K#2`b?BT M/ i?2B` BMi2`+iBQMX AKTmiiBQM rb T2`7Q`K2/ b2T`i2Hv T2` /Bb@ Q`/2` BM aSaa ky- mbBM; KmHiBTH2 BKTmiiBQM rBi? 6mHHv *QM/BiBQMH aT2+B}+iBQM #b2/ mTQM HBM2` `2;`2bbBQM BM Q`/2` iQ +`2i2 Ry BKTmi2/ /ib2ibX

aiiBbiB+H MHvbBb

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/2pBiBQM Q7 i?2 +?M;2 b+Q`2 Uk8VX

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9

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Rjy

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aiiBbiB+H MHvbBb

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/2pBiBQM Q7 i?2 +?M;2 b+Q`2 Uk8VX

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g= (1 − 3

4(n − 1) − 1) × SMD h?2 biM/`/ 2``Q` Q7 >2/;2bǶ ; rb +QKTmi2/ b 7QHHQrb (j3y),

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Rje OCD PTSD GAD SAD 23 24 25 26 72 74 76 78 22 23 24 25 26 75 80 85 90 95 0.0 0.5 1.0 1.5 2.0 0.0 0.5 1.0 1.5 2.0 Baseline score Hedges' g Drug Placebo

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0.0 0.2 0.4 0.6 0.8 5 10 15 20 Baseline score Remission rate Drug Placebo

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9

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