Pas, A.B. de
Citation
Pas, A. B. de. (2009, March 5). Spontaneous breathing and respiratory support of preterm infants at birth. Retrieved from
https://hdl.handle.net/1887/13595
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/13595
Note: To cite this publication please use the final published version (if applicable).
Effect of sustained inflation length on establishing functional residual capacity at birth in
ventilated premature rabbits
Arjan B te Pas*1,2, Melissa Siew3, Megan J Wallace3, Marcus, J Kitchen4, Andreas Fouras6, Robert A Lewis5, Naoto Yagi7, Kentaro Uesugi7, Susan Donath8, Peter G Davis1,
Colin J Morley1, Stuart B Hooper3
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submitted
Abstract
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Introduction
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Methods
Animal experiments
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h^bjaiVcZdjhan^bV\ZY#6[iZgi]ZZmeZg^bZci!ejehlZgZ`^aaZYWnVcZhi]Zi^XdkZg"YdhZ#
Plethysmography
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Mechanical ventilation
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Protocol
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Phase contrast X-ray imaging
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Analysis
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Results
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Group First inspiratory volume (ml/kg)
FRC 20 s (ml/kg)
FRC 1 min (ml/kg)
FRC 3 min (ml/kg)
FRC 7 min (ml/kg) CdH>
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0 0.5 1.0
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Time 2 mins A
B
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Lung gas volume (mL)Lung gas volume (mL)Lung gas volume (mL)Lung gas volume (mL)
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0 5 10 15 20 25
0 20 40 60 80 100 120
LLHS LRHS ULHS URHS
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Time (secs)
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a b c d
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t = 1 sec t = 5 sec t = 10 sec t = 20 sec
**
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a b c d
a b c d
t = 1 sec t = 5 sec t = 10 sec t = 20 sec
**
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e f g h
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0 100 200 300 400 0
2 4 6 8 10 12 14 16
FRC (mL/kg)
Time (secs)
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p(g)
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No SI 5 sec SI 10 sec SI 20 sec SI
Expired tidal volume (mL/kg)
Breath Number
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Discussion
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