Spontaneous breathing and respiratory support of preterm infants at birth Pas, A.B. de

Pas, A.B. de

Citation

Pas, A. B. de. (2009, March 5). Spontaneous breathing and respiratory support of preterm infants at birth. Retrieved from

https://hdl.handle.net/1887/13595

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13595

Note: To cite this publication please use the final published version (if applicable).

Early respiratory management of respiratory distress syndrome in very preterm infants

and bronchopulmonary dysplasia:

a case-control study

Arjan B. te Pas, Enrico Lopriore, Marissa J. Engbers, Frans J. Walther

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i]ZCZi]ZgaVcYh

PLoS ONE 2007;2:e192

Abstract

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Introduction

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Patients and Methods

Patients

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Data analysis

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 Results

Early respiratory management

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Earlyrespiratory

management



Intubation

<72hours

 RDS



Casecontrol

studypatients



262

included

87

Earlynasal

CPAP

(33%)

121

Intubation (46%)

1

(2%)

28

(32%)

121

(100%) 54

none

(21%)

1 25 83

268

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(cases)

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DRIgroup (matched

controls)

Early respiratory management

Intubation

<72 hours

RDS

Case-control study patients

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Figure 2#9^hig^Wji^dcd[YZa^kZgngddb^cijWVi^dc9G>!ZVgancVhVaXdci^cjdjhedh^i^kZV^glVnegZhhjgZVcY

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0 20 40 60 80 100 120 140

<28 wk 28-30 wk >30 wk

number of infants

n total

delivery room intubation n(%) early nasal CPAP n(%) early nasal CPAP-failure n(%)

Table 1#8dbeVg^hdcd[X]VgVXiZg^hi^Xhd[^c[Vcihl^i]G9Hl]d[V^aZYigZVibZcil^i]ZVgancVhVa8E6E:8;"

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Characteristic Group ECF

N = 25

Group DRI N = 50

Unvariate analysis (P)

7L!\ &(.(£(,. &'+&£(.* CH

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gZiVgYVi^dc#

Table 2#EjabdcVgnX]VgVXiZg^hi^Xhd[cZdcViZhl^i]G9Hl]d[V^aZYZVgancVhVa8E6EigZVibZci:8;"\gdje

VcYbViX]ZY^c[Vcihl]dlZgZ^cijWViZY^ci]ZYZa^kZgngddb9G>"\gdje#

Pulmonary clinical course parameters ECF N = 25

DRI N = 50

Unvariate analysis (P)

Hjg[VXiVci!cYdhZh &#%£%#* &#+£%#- 1%#%%&

=;DKgZhXjZ!c (&' &*(% CH

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i^aVi^dc#

Table 3#Eg^bVgndjiXdbZd[^c[Vcihl]d[V^aZYZVgancVhVa8E6EigZVibZci:8;"\gdjeVcYbViX]ZY^c[Vcih

l]dlZgZ^cijWViZY^ci]ZYZa^kZgngddb9G>"\gdje##

Primary outcome ECF

N = 25

DRI N = 50

Unvariate analysis (P)

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Discussion

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Acknowledgement

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VYk^XZ#



Reference List

 &# I]Z>ciZgcVi^dcVaA^V^hdc8dbb^iiZZdcGZhjhX^iVi^dc>A8DGXdchZchjhdchX^ZcXZl^i]igZVibZcigZX"

dbbZcYVi^dch[dgeZY^Vig^XVcYcZdcViVaeVi^Zcih/cZdcViVagZhjhX^iVi^dc#EZY^Vig^Xh'%%+BVn0&&,*/

Z.,-"Z.--#

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