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Cardiac Resynchronization Therapy

Molhoek, S.G.

Citation

Molhoek, S. G. (2005, June 23). Cardiac Resynchronization Therapy. Retrieved from https://hdl.handle.net/1887/2715

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesisin the Institutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/2715

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Stellingen

Behorende bij het proefschrift,

Cardiac Resynchronization Therapy

a Novel Treatment Option for Congestive Heart Failure

van S.G.Molhoek

 Screening for eligibility of cardiac resynchronization therapy (CRT) should be consid-ered in patients with heart failure scheduled for ICD implantation.(This thesis)

 CRT results in improvement of clinical symptoms and quality of life, accompanied by improvement in 6-minute walking distance and LVEF. These effects are maintained at long-term follow-up.(This thesis)

Still 20-30% of the patients treated with CRT do not respond. Accordingly, the cur-rent selection criteria need to be refined.(This thesis)

 Tissue Doppler Imaging can be used to identify patients who benefit from CRT. (This thesis)

 At this time 2% of all hospital admissions (medical and surgical) and 5% of all medical admissions are heart failure related. (Brown A et al., Eur Heart J 1998;19:1063-9)

 In patients with end-stage heart failure, multisite pacing may be associated with a rapid and sustained hemodynamic improvement. (Cazeau S et al., Pacing Clin Electrophysi-ol 1996;19:1748-1757)

 CRT is the best new therapeutical invention for congestive heart failure since the Beta-blockers. (Abraham WT, conference of the ESC sept 2002, Berlin)

 CRT alone or combined with an ICD reduces the composite end point off death of

any cause or hospitalization during a mean follow-up of 16 months. (Bristow MR et al. for the COMPANION Investigators, N Engl J Med 2004;350:2140-2150)

We`re all living in Amerika. Amerika ist wunderbahr! (Rammstein 2005)  Je doet iets of je doet het niet. (J.Cruijff 2004)

 Als je ontspannen bent en vertrouwen hebt in het resultaat, is bunkerspel (net als een promotie) echt niet moeilijk.

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