Cover Page
The handle http://hdl.handle.net/1887/68471 holds various files of this Leiden University
dissertation.
Author: Zhang, X.
EXPANDING THE CAPABILITIES
OF ARTERIAL SPIN LABELING MRI
Expanding the capabilities of Arterial Spin Labeling MRI Thesis, Leiden University Medical Center, The Netherlands ISBN: 978-94-92801-69-2
Printed by: Proefschrift-aio.nl
Copyright ©2018, Xingxing Zhang, Leiden, The Netherlands
The copyright of some of the articles that have been accepted for publication or that have been published, has been transferred to the respective journals The studies performed in this thesis were performed at the C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, the Netherlands.
EXPANDING THE CAPABILITIES
OF ARTERIAL SPIN LABELING MRI
Proefschrift
ter verkrijging van de graad van doctor aan de Universiteit Leiden
op gezag van de Rector Magnificus prof.mr. C.J.J.M. Stolker volgens besluit van het college voor promoties
te verdedigen op januari 31, 2019 klokke 13:45
door Xingxing Zhang geboren te Jiangsu, China
Promotor:
Prof. Dr. A. G. Webb Co-promotor:
Prof. Dr. Ir. M. J. P. van Osch Promotiecommissie: Prof. Dr. J. Hendrikse Dr. M. Smits
Contents
1. General introduction and outline
2. Fast cerebral flow territory mapping using vessel encoded dynamic arterial spin labeling (VE-DASL)
3. Time efficient measurement of multi-phase arterial spin labeling MR-signal in white matter
4. Comparison of perfusion signal acquired by ASL prepared IVIM and conventional IVIM to unravel the origin of the IVIM-signal
5. Measure Labeling Efficiency for Pseudo-continuous Arterial Spin Labeling
6. In vivo blood T1 measurements at 1.5 T, 3 T, and 7 T
7. Discussion and Summary