University of Groningen
Biliary atresia: neurodevelopment and quality of life
Rodijk, Lyan
DOI:
10.33612/diss.133865199
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Publication date:
2020
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Citation for published version (APA):
Rodijk, L. (2020). Biliary atresia: neurodevelopment and quality of life. University of Groningen.
https://doi.org/10.33612/diss.133865199
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Biliary atresia:
neurodevelopment and quality of life
Rodijk, Lyan H.
Biliary atresia: neurodevelopment and quality of life PhD dissertation, University of Groningen, The Netherlands
ISBN: 978-94-6416-104-5 (printed version) ISBN: 978-94-6416-118-2 (electronic version)
The research described in this thesis is supported by a grant of the Dutch Digestive Foundation (Maag Lever Darm stichting). Lyan H. Rodijk received a MD/PhD scholarship of the University of Groningen. Financial support for the printing of this thesis was kindly provided by the University Medical Center Groningen, the Graduate School of Medical Sciences, and the University of Groningen. All support is gratefully acknowledged.
Layout and cover design: H.J. Makken | persoonlijkproefschrift.nl Printed by: Ridderprint | www.ridderprint.nl
B.V. Copyright © Lyan H. Rodijk, Groningen, the Netherlands 2020
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, without written permission of the author or, when appropriate, of the publisher of the published articles.
Biliary atresia:
neurodevelopment and quality of life
Proefschrift
ter verkrijging van de graad van doctor aan de
Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
woensdag 7 oktober 2020 om 14.30 uur
door
Lyan Hendrika Rodijk
geboren op 16 maart 1993
te Hellendoorn
Promotores
Prof. dr. J.B.F. Hulscher
Prof. dr. H.J. Verkade
Copromotor
Dr. J.L.M. Bruggink
Beoordelingscommissie
Prof. dr. O.F. Brouwer
Prof. dr. A.A.E. Verhagen
Prof. dr. M.P. Pakarinen
Paranimfen
Nicole Rodijk
Sanne Rodijk
Paranimfen
Nicole Rodijk
Sanne Rodijk
Table of Contents
Chapter 1. Introduction and thesis outline 6
Part I. A systematic review of the literature 20
Chapter 2. Neurodevelopmental outcomes in children with liver diseases:
a systematic review
22
Part II. Neurodevelopmental outcomes in children with biliary atresia 50 Chapter 3. Early motor repertoire in infants with biliary atresia:
a nationwide prospective cohort study
52
Chapter 4. Predictability of neurodevelopmental outcomes in patients
with biliary atresia: a nationwide prospective cohort study
68
Chapter 5. Long-term neurodevelopmental outcomes in children
with biliary atresia
88
Part III. The impact of biliary atresia on quality of life and family functioning
110 Chapter 6. Health-related quality of life in biliary atresia patients
with native liver or transplantation
112 Chapter 7. Parental wellbeing after diagnosing a child with biliary atresia:
a longitudinal nationwide cohort study
140
Chapter 8. Quality of life in parents of children with biliary atresia 164
Chapter 9. General discussion and future perspectives 182
Chapter 10. English summary 210
Appendices Nederlandse samenvatting 216
Dankwoord 222
Contributions to the field 226
