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To approach or to avoid : neurobiological mechanisms in social anxiety Peer, J.M. van

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(1)To approach or to avoid : neurobiological mechanisms in social anxiety Peer, J.M. van. Citation Peer, J. M. van. (2009, December 8). To approach or to avoid : neurobiological mechanisms in social anxiety. Retrieved from https://hdl.handle.net/1887/14486 Version:. Not Applicable (or Unknown). License:. Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden. Downloaded from:. https://hdl.handle.net/1887/14486. Note: To cite this publication please use the final published version (if applicable)..

(2) Chapter 7. Cortisol administration enhances the coupling of midfrontal delta and beta oscillations..   ƒ†ƒ’–‡†˜‡”•‹‘‘ˆ–Š‹• Šƒ’–‡”‹•’—„Ž‹•Š‡†‹

(3) –‡”ƒ–‹‘ƒŽ ‘—”ƒŽ‘ˆ•› Š‘’Š›•‹‘Ž‘‰›ȋʹͲͲͺȌǡ͸͹ǡͳͶͶǦͳͷͲǡ †‘‹ǣͳͲǤͳͲͳ͸ȀŒǤ‹Œ’•› Š‘ǤʹͲͲ͹ǤͳͳǤͲͲͳ ǤǤ˜ƒ‡‡”ǡǤ‘‡Ž‘ˆ•ǡƬŠǤ’‹Š‘˜‡.

(4) Chapter7. Abstract  Š‡”‡ ‹• ‹ ”‡ƒ•‹‰ ‡˜‹†‡ ‡ –Šƒ– –Š‡ •–”‡‰–Š ‘ˆ –Š‡ ”‡Žƒ–‹‘ „‡–™‡‡ •Ž‘™ ȋȌ ƒ† ˆƒ•– ȋ Ȍ ™ƒ˜‡ ƒ –‹˜‹–› ‹ –Š‡   ‹• ƒ••‘ ‹ƒ–‡† ™‹–Š •’‡ ‹ˆ‹  ‘–‹˜ƒ–‹‘ƒŽ •–ƒ–‡• ƒ† –Š‡‹” ‘””‡•’‘†‹‰ ‡—”‘‡†‘ ”‹‡ ’ƒ––‡”•Ǥ Šƒ ‡† ‘””‡Žƒ–‹‘• „‡–™‡‡  ƒ†  Šƒ˜‡ „‡‡ ”‡Žƒ–‡† –‘ ƒš‹‡–›ǡ „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘ ƒ† Š‹‰Š „ƒ•ƒŽ ‘”–‹•‘Ž Ž‡˜‡Ž•Ǥ ‘™‡˜‡”ǡ–Š‡†‹”‡ –‡ˆˆ‡ –•‘ˆ ‘”–‹•‘Ž‘Ȃ  ‘—’Ž‹‰Šƒ˜‡‘–„‡‡‡š’‡”‹‡–ƒŽŽ› •–—†‹‡† ›‡–Ǥ Š‡ ’”‡•‡– •–—†› ‹˜‡•–‹‰ƒ–‡† ™Š‡–Š‡” ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ‹ ”‡ƒ•‡• Ȃ  ‘—’Ž‹‰Ǥ ‡•–‹‰ •–ƒ–‡   ”‡ ‘”†‹‰• ™‡”‡ ‘„–ƒ‹‡† ˆ”‘ ͶͲ ”‹‰Š–ǦŠƒ†‡† Š‡ƒŽ–Š› ƒŽ‡ ’ƒ”–‹ ‹’ƒ–• ™‹–Š ‡š–”‡‡ Ž‘™ ‘” Š‹‰Š • ‘”‡• ‘ ƒ „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘ • ƒŽ‡ǡ ƒˆ–‡” ’Žƒ ‡„‘ ƒ† ‘”–‹•‘Ž ȋͷͲ ‰Ȍ ƒ†‹‹•–”ƒ–‹‘Ǥ • ‡š’‡ –‡†ǡ †‡Ž–ƒȂ„‡–ƒ ‘””‡Žƒ–‹‘ –‡†‡† –‘ „‡ Š‹‰Š‡” ‹ Š‹‰Š ‘’ƒ”‡† –‘ Ž‘™ „‡Šƒ˜‹‘”ƒŽŽ› ‹Š‹„‹–‡† ȋ

(5) Ȍ ’ƒ”–‹ ‹’ƒ–•Ǥ

(6)  ƒ††‹–‹‘ǡ ‘”–‹•‘Ž ”‡•—Ž–‡† ‹ ƒ ‹ ”‡ƒ•‡ ‹ ‘””‡Žƒ–‹‘ „‡–™‡‡  ȋ†‡Ž–ƒȌƒ† ȋ„‡–ƒȌƒ –‹˜‹–› ‘’ƒ”‡†–‘’Žƒ ‡„‘ǡ‡•’‡ ‹ƒŽŽ›‹Š‹‰Š

(7) ’ƒ”–‹ ‹’ƒ–•Ǥ ‘•‡“—‡–Ž›ǡ –Š‡ ‰”‘—’ †‹ˆˆ‡”‡ ‡• ™‡”‡ ‘•– ’”‘‘— ‡† ƒˆ–‡” ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ǤŠ‡•‡”‡•—Ž–••—‰‰‡•––Šƒ– ‘”–‹•‘Ž ƒ‘†‹ˆ›„”ƒ‹ƒ –‹˜‹–›ǡ‹ ”‡ƒ•‹‰ƒ ’ƒ––‡” ƒ••‘ ‹ƒ–‡† ™‹–Š ƒš‹‡–› ƒ† „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘Ǥ Š‹• ‹• ‹ Ž‹‡ ™‹–Š ˆ‹†‹‰• ƒ••‘ ‹ƒ–‹‰ ‘”–‹•‘Ž™‹–Š„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘ƒ†ƒš‹‡–›Ǥ. ͳ͵ʹ.

(8) Cortisolenhancesdeltabetacorrelation. Introduction  Š‡”‡ ‹• ‹ ”‡ƒ•‹‰ ‡˜‹†‡ ‡ –Šƒ– –Š‡ •–”‡‰–Š ‘ˆ –Š‡ ”‡Žƒ–‹‘ „‡–™‡‡ •Ž‘™ ȋȌ ƒ† ˆƒ•– ȋ Ȍ ™ƒ˜‡ ƒ –‹˜‹–› ‹ –Š‡   ‹• ƒ••‘ ‹ƒ–‡† ™‹–Š •’‡ ‹ˆ‹  ‘–‹˜ƒ–‹‘ƒŽ •–ƒ–‡• ƒ† –Š‡‹” ‘””‡•’‘†‹‰‡—”‘‡†‘ ”‹‡’ƒ––‡”•ǤŠƒ ‡†Ǧ  ‘””‡Žƒ–‹‘•Šƒ˜‡„‡‡ ”‡Žƒ–‡†–‘ƒš‹‡–›ƒ†„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘ȋ›ƒœ‡˜ƬŽ‘„‘†•ƒ›ƒǡʹͲͲ͵Ǣ›ƒœ‡˜‡– ƒŽǤǡʹͲͲ͵Ǣ›ƒœ‡˜ǡƒ˜‘•–›ƒ‘˜ǡƬ‡˜‹ǡʹͲͲͶǢ›ƒœ‡˜ǡ Š—––‡”ǡƬƒ ‘ǡʹͲͲ͸Ȍǡ ƒ†™‡”‡”‡ ‡–Ž›ˆ‘—†‹Š‡ƒŽ–Š›’ƒ”–‹ ‹’ƒ–•™‹–ŠŠ‹‰Š„ƒ•ƒŽ ‘”–‹•‘ŽŽ‡˜‡Ž•ȋ Š—––‡” Ƭƒ ‘ǡʹͲͲͷȌǤŠ‹•‹•ƒ‹’‘”–ƒ–ˆ‹†‹‰ǡƒ•Š‹‰Š ‘”–‹•‘ŽŽ‡˜‡Ž•Šƒ˜‡„‡‡”‡Žƒ–‡† –‘„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘ƒ†ƒš‹‡–›ȋ‡Ǥ‰Ǥǡ‘”–‡ǡʹͲͲͳǢƒ’‘Ž•›ǡͳͻͻͲǢƒ ‘‡–ƒŽǤǡ ͳͻͻͺȌǤ ƒ•‡† ‘ –Š‹• ˆ‹†‹‰ǡ  Š—––‡” Ƭ ƒ ‘ ȋʹͲͲͷȌ •—‰‰‡•–‡† –Šƒ– ‘”–‹•‘Ž ‡Šƒ ‡• Ǧ  ‘—’Ž‹‰Ǥ ‘™‡˜‡”ǡ –Š‡ †‹”‡ – ‡ˆˆ‡ –• ‘ˆ ‘”–‹•‘Ž ‘ Ǧ  ‘—’Ž‹‰ Šƒ˜‡‘–„‡‡‡š’‡”‹‡–ƒŽŽ›•–—†‹‡†›‡–Ǥ

(9) –Š‡’”‡•‡–•–—†›™‡–Š‡”‡ˆ‘”‡‹˜‡•–‹‰ƒ–‡† ™Š‡–Š‡” ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘‹ ”‡ƒ•‡•Ǧ  ‘—’Ž‹‰Ǥ Ž‘™ƒ†ˆƒ•– ™ƒ˜‡•ƒ”‡–Š‘—‰Š––‘„‡‰‡‡”ƒ–‡†„›•‡’ƒ”ƒ–‡‡—”ƒŽ•›•–‡• ™‹–Š †‹ˆˆ‡”‡– ˆ— –‹‘ƒŽ ’”‘’‡”–‹‡• ȋ‡Ǥ‰Ǥǡ ƒçƒ”ǡ ʹͲͲ͸Ǣ ƒçƒ”ǡ ƒçƒ”Ǧ”‘¼Ž—ǡ ƒ”ƒƒçǡ Ƭ  Šò”ƒǡʹͲͲͲǢŽ‹‡• ŠǡͳͻͻͻǢƒ—ˆ•‡–ƒŽǤǡʹͲͲ͵Ǣ‘’‡•†ƒ‹Ž˜ƒǡͳͻͻͳȌǤŽ–Š‘—‰Š–Š‡ •’‡ ‹ˆ‹ „”ƒ‹”‡‰‹‘•‹˜‘Ž˜‡†‹–Š‡•‡•›•–‡•ƒ†–Š‡‹”•’‡ ‹ˆ‹ ˆ— –‹‘•ƒ”‡•–‹ŽŽ‘– ‘’Ž‡–‡Ž› —†‡”•–‘‘†ǡ •‘‡ ƒ—–Š‘”• Šƒ˜‡ •—‰‰‡•–‡† –Šƒ–  ȋ†‡Ž–ƒ ƒ† –Š‡–ƒȌ ‘• ‹ŽŽƒ–‹‘•ƒ”‡  ‘””‡Žƒ–‡•‘ˆ‘–‹˜ƒ–‹‘ƒŽƒ†‡‘–‹‘ƒŽ’”‘ ‡••‡•ƒ••‘ ‹ƒ–‡†™‹–Š •—„ ‘”–‹ ƒŽ ƒ –‹˜‹–›ǡ ™Š‡”‡ƒ•  ȋƒŽ’Šƒ ƒ† „‡–ƒȌ ‘• ‹ŽŽƒ–‹‘• ƒ”‡ ‘””‡Žƒ–‡• ‘ˆ ‘”‡ ‘‰‹–‹˜‡ ’”‘ ‡••‡• ƒ••‘ ‹ƒ–‡† ™‹–Š ‘”–‹ ƒŽ ƒ –‹˜‹–› ȋ‡Ǥ‰Ǥǡ ƒ› Ƭ ‘Ž‡ǡ ͳͻͺͷǢ ‘„‹•‘ǡ ͳͻͻͻǡ ʹͲͲͲǡ ʹͲͲͳǢ ›ƒœ‡˜ǡ ʹͲͲ͹Ǣ ›ƒœ‡˜ Ƭ Ž‘„‘†•ƒ›ƒǡ ʹͲͲ͵Ǣ ‡—’‡” Ƭ ˆ—”–• Š‡ŽŽ‡”ǡʹͲͲͳȌǤ ‹‰Š‡””‡Žƒ–‹˜‡ƒ’Ž‹–—†‡•‘ˆƒ‰‹˜‡ˆ”‡“—‡ ›‹–Š‡ ‹†‹ ƒ–‡‘”‡ƒ –‹˜‹–› ‹ –Š‡ —†‡”Ž›‹‰ •›•–‡ǡ ™Š‹ Š ”‡†‡”• ‹– ‘”‡ Ž‹‡Ž› –Šƒ– ƒ „‡Šƒ˜‹‘”ƒŽ ’ƒ––‡” ƒ••‘ ‹ƒ–‡† ™‹–Š –Š‹• •›•–‡ ™‹ŽŽ ‘ —”Ǥ ‡Žƒ–‹˜‡  ƒ†    •’‡ –”ƒŽ ’‘™‡” ƒ› –Š—• •‡”˜‡ ƒ• ƒ ‡ƒ•—”‡ ‘ˆ ’”‡†‹•’‘•‹–‹‘ –‘ ƒ •’‡ ‹ˆ‹  „‡Šƒ˜‹‘”ƒŽ •–›Ž‡ ȋ›ƒœ‡˜ Ƭ Ž‘„‘†•ƒ›ƒǡ ʹͲͲ͵ȌǤ ‘•‹•–‡– ™‹–Š –Š‹• ’”‘’‘•‹–‹‘ǡ ‡ƒ•—”‡• ‘ˆ ‡š–”ƒ˜‡”•‹‘ ƒ† „‡Šƒ˜‹‘”ƒŽƒ –‹˜ƒ–‹‘Šƒ˜‡„‡‡ˆ‘—†–‘„‡positively”‡Žƒ–‡†–‘ȋȌ†‡Ž–ƒ’‘™‡”ǡƒ† negatively–‘ȋ ȌƒŽ’Šƒ’‘™‡”Ǥ

(10)  ‘–”ƒ•–ǡ‡—”‘–‹ ‹•ǡ„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘ƒ†–”ƒ‹– ƒš‹‡–› Šƒ˜‡ „‡‡ ˆ‘—† –‘ „‡ negatively ”‡Žƒ–‡† –‘ ȋȌ †‡Ž–ƒ ƒ† –Š‡–ƒ ’‘™‡”ǡ ƒ†. ͳ͵͵.

(11) Chapter7. positively –‘ ȋ Ȍ ƒŽ’Šƒ ƒ† „‡–ƒ ’‘™‡” ȋ›ƒœ‡˜ǡ Ž‘„‘†•ƒ›ƒǡ Ƭ ‹Ž•‘ǡ ʹͲͲʹǢ ›ƒœ‡˜‡–ƒŽǤǡʹͲͲ͵ǡʹͲͲͶȌǤ ‘”‡‘˜‡”ǡ –Š‡ ”‡Žƒ–‹‘•Š‹’ „‡–™‡‡  ƒ†  •’‡ –”ƒŽ ’‘™‡” ƒ› ’”‘˜‹†‡ ‹•‹‰Š–‹–‘–Š‡„ƒŽƒ ‡‘”‹–‡”ƒ –‹‘‘ˆƒ –‹˜‹–›‹–Š‡—†‡”Ž›‹‰•›•–‡•Ǥ ‘”‡šƒ’Ž‡ǡ ”‡Žƒ–‹˜‡Ž› Š‹‰Š Ǧ–‘Ǧ  ”ƒ–‹‘• Šƒ˜‡ „‡‡ ƒ••‘ ‹ƒ–‡† ™‹–Š ‹ ”‡ƒ•‡† ”‹•Ǧ–ƒ‹‰ „‡Šƒ˜‹‘” ƒ† ‹’—Ž•‹˜‹–› ‹ Š‡ƒŽ–Š› ’ƒ”–‹ ‹’ƒ–• ȋ Š—––‡” Ƭ ƒ ‘ǡ ʹͲͲͷȌ ƒ† ’ƒ–‹‡–• ™‹–Š ƒ––‡–‹‘ †‡ˆ‹ ‹– Š›’‡”ƒ –‹˜‹–› †‹•‘”†‡” ȋ•‡‡ ‡Ǥ‰Ǥǡ ‘‘ǡ ‘’ˆ‡”ǡ ‡ƒŽ‡ǡ Ƭ ‡‹–‡ǡ ʹͲͲͶ ˆ‘” ƒ ‘˜‡”˜‹‡™ȌǤ

(12)  ƒ††‹–‹‘ǡ –Š‡ •–”‡‰–Š ‘ˆ –Š‡ ”‡ ‹’”‘ ƒŽ ”‡Žƒ–‹‘•Š‹’ „‡–™‡‡ȋ ȌƒŽ’Šƒƒ†ȋȌ†‡Ž–ƒ‘• ‹ŽŽƒ–‹‘•ȋ‹ƒ˜‡”ƒ‰‡†‡˜‘‡†’‘–‡–‹ƒŽ•ƒ•™‡ŽŽ ƒ• ‹ ”‡•–‹‰ •–ƒ–‡  Ȍ Šƒ• „‡‡ ˆ‘—† –‘ „‡ negatively ”‡Žƒ–‡† –‘ ‡š–”ƒ˜‡”•‹‘ ƒ† „‡Šƒ˜‹‘”ƒŽƒ –‹˜ƒ–‹‘ȋ›ƒœ‡˜‡–ƒŽǤǡʹͲͲ͵Ǣ‘„‹•‘ǡͳͻͻͻǡʹͲͲͳȌƒ†–‘„‡positively ”‡Žƒ–‡†–‘‡—”‘–‹ ‹•ǡ„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘ƒ†–”ƒ‹–ƒš‹‡–›ȋ›ƒœ‡˜ƬŽ‘„‘†•ƒ›ƒǡ ʹͲͲ͵Ǣ›ƒœ‡˜‡–ƒŽǤǡʹͲͲ͵ǡʹͲͲͶǡʹͲͲ͸ȌǤ‹‹Žƒ”Ž›ǡ‡š’‡”‹‡–ƒŽƒ‹’—Žƒ–‹‘‘ˆƒš‹‘—• ƒ’’”‡Š‡•‹‘ȋ„›‰‹˜‹‰’ƒ”–‹ ‹’ƒ–•”ƒ†‘‡‰ƒ–‹˜‡ˆ‡‡†„ƒ ‘–Š‡‹”’‡”ˆ‘”ƒ ‡Ȍ Šƒ• „‡‡ ˆ‘—† –‘ •‹‰‹ˆ‹ ƒ–Ž› ‹ ”‡ƒ•‡ –Š‡ ‘””‡Žƒ–‹‘ „‡–™‡‡ ȋȌ †‡Ž–ƒ ƒ† ȋ Ȍ „‡–ƒ •’‡ –”ƒŽ ’‘™‡” ȋ‹Ǥ‡Ǥǡ †‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰Ȍ ‘’ƒ”‡† –‘ „ƒ•‡Ž‹‡ ȋ’”‡Ǧˆ‡‡†„ƒ Ȍ ‡ƒ•—”‡‡–•ȋ›ƒœ‡˜‡–ƒŽǤǡʹͲͲ͸ȌǤ ‡ ƒ—•‡ –Š‡•‡ ‘–‹˜ƒ–‹‘ƒŽ •–ƒ–‡• ȋ‹Ǥ‡Ǥǡ „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘ ƒ† ƒš‹‡–› ‘ –Š‡ ‘‡ Šƒ† ƒ† „‡Šƒ˜‹‘”ƒŽ †‹•‹Š‹„‹–‹‘ ‘” ‹’—Ž•‹˜‹–› ‘ –Š‡ ‘–Š‡” Šƒ†Ȍ Šƒ˜‡ „‡‡ ƒ••‘ ‹ƒ–‡†™‹–Š•’‡ ‹ˆ‹ ‡—”‘‡†‘ ”‹‡’ƒ––‡”•ǡ Š—––‡”ƒ†ƒ ‘ȋʹͲͲͶǡʹͲͲͷȌ Š›’‘–Š‡•‹œ‡†–Šƒ––Š‡•–”‡‰–Š‘ˆ–Š‡”‡Žƒ–‹‘•Š‹’„‡–™‡‡ƒ† ƒ –‹˜‹–›ƒ›ƒŽ•‘ ˜ƒ”› ƒ• ƒ ˆ— –‹‘ ‘ˆ –Š‡•‡ ‡—”‘‡†‘ ”‹‡ ’ƒ––‡”•Ǥ Š‡ ”‡•—Ž–• ‘ˆ –™‘ •–—†‹‡• •—’’‘”–‡† –Š‹• Š›’‘–Š‡•‹•ǣ †‹‹•–”ƒ–‹‘ ‘ˆ –‡•–‘•–‡”‘‡ǡ ƒ †”—‰ ™‹–Š Ž‡ƒ” †‹•‹Š‹„‹–‘”› ƒ† ƒš‹‘Ž›–‹  ’”‘’‡”–‹‡• ȋ‡Ǥ‰Ǥǡ ‡”ƒ•ǡ —–ƒǡ ƒƒ•ǡ ‘’’‡• Šƒƒ”ǡ Ƭ ƒ ‘ǡʹͲͲ͸Ǣ˜‡••‘ǡ‡••‘ǡ‰‡ŽǡƬ‘†‡”’ƒŽǡʹͲͲ͵Ǣƒ ‘‡–ƒŽǤǡʹͲͲͶȌǡ –‘Š‡ƒŽ–Š›˜‘Ž—–‡‡”•™ƒ•ˆ‘—†–‘”‡•—Ž–‹ƒ†‡ ”‡ƒ•‡‹–Š‡”‡Žƒ–‹‘„‡–™‡‡†‡Ž–ƒƒ† „‡–ƒ•’‡ –”ƒŽ’‘™‡”ǡ”‡•—Ž–‹‰‹ƒ‘Ǧ•‹‰‹ˆ‹ ƒ–†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ȋ‹Ǥ‡Ǥǡ†‡Ž–ƒǦ„‡–ƒ de ‘—’Ž‹‰Ȍ ȋ Š—––‡” Ƭ ƒ ‘ǡ ʹͲͲͶȌǤ

(13)  ‘–”ƒ•–ǡ ‘’ƒ”‹‰ –Š‡ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘‹Š‡ƒŽ–Š›’ƒ”–‹ ‹’ƒ–•™‹–ŠŠ‹‰Šƒ†Ž‘™„ƒ•ƒŽ ‘”–‹•‘ŽŽ‡˜‡Ž•ǡ Š—––‡”ƒ† ƒ ‘ȋʹͲͲͷȌˆ‘—†Š‹‰Š ‘”–‹•‘ŽŽ‡˜‡Ž•–‘„‡ƒ••‘ ‹ƒ–‡†™‹–Šƒ•‹‰‹ˆ‹ ƒ–†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ȋ‹Ǥ‡Ǥǡ†‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰Ȍǡ™Š‡”‡ƒ•Ž‘™ ‘”–‹•‘ŽŽ‡˜‡Ž•™‡”‡ƒ••‘ ‹ƒ–‡†™‹–Š –Š‡ ƒ„•‡ ‡ ‘ˆ †‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰Ǥ Š‡ Žƒ––‡” ˆ‹†‹‰ ‹• ‹ ƒ‰”‡‡‡– ™‹–Š ˆ‹†‹‰• ƒ••‘ ‹ƒ–‹‰ –Š‡ •–”‡••ǦŠ‘”‘‡ ‘”–‹•‘Ž ™‹–Š „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘ ƒ† ƒš‹‡–› ȋ‡Ǥ‰Ǥǡ. ͳ͵Ͷ.

(14) Cortisolenhancesdeltabetacorrelation. ‘”–‡ǡ ʹͲͲͳǢ ƒ’‘Ž•›ǡ ͳͻͻͲǢ ƒ ‘ ‡– ƒŽǤǡ ͳͻͻͺȌ ƒ† •—‰‰‡•–• –Šƒ– ‘”–‹•‘Ž ƒ ‘†‹ˆ› „”ƒ‹ ƒ –‹˜‹–›ǡ ‹ ”‡ƒ•‹‰ ƒ ’ƒ––‡” ƒ••‘ ‹ƒ–‡† ™‹–Š ƒš‹‡–› ƒ† „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘Ǥ — Š ˆ‹†‹‰ •—’’‘”–• –Š‡ ‹’‘”–ƒ– ‹ˆŽ—‡ ‡ ‘ˆ ‘”–‹•‘Ž ‘ ‘‰‹–‹‘ǡ ‡‘–‹‘ ’”‘ ‡••‹‰ ƒ† „‡Šƒ˜‹‘” ȋ‡Ǥ‰Ǥǡ ‡ Ž‘‡– ‡– ƒŽǤǡ ͳͻͻͻǢ ”‹ •‘ǡ ”‡˜‡–•ǡ Ƭ  Š—Ž‹ǡʹͲͲ͵ȌǤ ‘™‡˜‡”ǡ Š—––‡”ƒ†ƒ ‘ȋʹͲͲͷȌ—•‡†ƒ ”‘••Ǧ•‡ –‹‘ƒŽ†‡•‹‰ ƒ†ǡƒ•ƒ”‡•—Ž–ǡ–Š‡‰”‘—’†‹ˆˆ‡”‡ ‡•„‡–™‡‡’ƒ”–‹ ‹’ƒ–•™‹–ŠŠ‹‰Šƒ†Ž‘™ ‘”–‹•‘Ž Ž‡˜‡Ž• ƒ› „‡ †—‡ –‘ ˆƒ –‘”• ‘–Š‡” –Šƒ „ƒ•ƒŽ ‘”–‹•‘Ž Ž‡˜‡Ž• ƒ• ™‡ŽŽǤ ‘ ‡ƒ„Ž‡ ‘”‡ ‘ Ž—•‹˜‡‹–‡”’”‡–ƒ–‹‘•‘ˆ–Š‡‡ˆˆ‡ –•‘ˆ ‘”–‹•‘Ž‘–Š‡ ‘””‡Žƒ–‹‘„‡–™‡‡†‡Ž–ƒƒ† „‡–ƒƒ –‹˜‹–›ǡ‹–‡‡†•–‘„‡•Š‘™™Š‡–Š‡” ‘”–‹•‘Žadministration ƒƒŽ•‘‹ ”‡ƒ•‡–Š‹• ‘””‡Žƒ–‹‘Ǥ Š‡ ƒ‹ ’—”’‘•‡ ‘ˆ –Š‡ ’”‡•‡– •–—†› ™ƒ• –‘ ‹˜‡•–‹‰ƒ–‡ ™Š‡–Š‡” ‘”–‹•‘Ž ƒ ‡Šƒ ‡ †‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰ „› ƒ†‹‹•–”ƒ–‹‘ ‘ˆ ‘”–‹•‘Ž ‹ ƒ ™‹–Š‹Ǧ•—„Œ‡ –ǡ ’Žƒ ‡„‘Ǧ ‘–”‘ŽŽ‡† †‡•‹‰Ǥ

(15)  Ž‹‡ ™‹–Š –Š‡ ˆ‹†‹‰• ‘ˆ  Š—––‡” ƒ† ƒ ‘ ȋʹͲͲͷȌǡ ™‡ ‡š’‡ –‡†–‘ˆ‹†ƒ‹ ”‡ƒ•‡††‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ƒˆ–‡” ‘”–‹•‘Ž ‘’ƒ”‡†–‘’Žƒ ‡„‘Ǥ ‡ ‘†ǡ•‹ ‡ ‘”–‹•‘ŽŠƒ•„‡‡’”‘’‘•‡†ƒ•ƒ‡†‘ ”‹‘Ž‘‰‹ ƒŽƒ”‡”ˆ‘”„‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘ ƒ† ƒš‹‡–› ȋ‡Ǥ‰Ǥǡ ‘”–‡ǡ ʹͲͲͳǢ ƒ’‘Ž•›ǡ ͳͻͻͲǢ ƒ ‘ ‡– ƒŽǤǡ ͳͻͻͺȌǡ ƒ† •‹ ‡ ‹ ”‡ƒ•‡† †‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰ Šƒ• „‡‡ ˆ‘—† ‹ Š‹‰Š ƒš‹‘—• ’ƒ”–‹ ‹’ƒ–• —†‡” ‘†‹–‹‘•‘ˆ— ‡”–ƒ‹–›ȋ›ƒœ‡˜‡–ƒŽǤǡʹͲͲ͸Ȍǡ™‡ƒ‹‡†–‘‹˜‡•–‹‰ƒ–‡™Š‡–Š‡”Š‹‰Š †‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰™‘—Ž†ƒŽ•‘„‡ƒ••‘ ‹ƒ–‡†™‹–ŠŠ‹‰Š„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘Ǥ. MaterialsandMethods Participants ‘”–› ƒŽ‡ •–—†‡–• ”‡ ”—‹–‡† ˆ”‘ –Š‡ ‹˜‡”•‹–› ‘ˆ ‡‹†‡ ’ƒ”–‹ ‹’ƒ–‡† ‹ –Š‡ •–—†›ˆ‘”ˆ‹ƒ ‹ƒŽ‘” ‘—”•‡ ”‡†‹–Ǥ‡•‡Ž‡ –‡†ƒ’”‹‘”‹ʹͲ•–—†‡–•™‹–ŠŽ‘™• ‘”‡•ȋζ ͳ͸Ȍ ƒ† ʹͲ •–—†‡–• ™‹–Š Š‹‰Š • ‘”‡• ȋη ʹͳȌ ‘ –Š‡ ‡Šƒ˜‹‘”ƒŽ

(16) Š‹„‹–‹‘  ƒŽ‡ ȋ

(17) ǣ ƒ”˜‡”ƬŠ‹–‡ǡͳͻͻͶȌǤͳŽŽ’ƒ”–‹ ‹’ƒ–•™‡”‡”‹‰Š–ǦŠƒ†‡†ǡŠƒ†ƒ„‘†›™‡‹‰Š–„‡–™‡‡ ͸ͲǦͺͷ ‰ǡ ƒ† ™‡”‡ • ”‡‡‡† –‘ ‡š Ž—†‡ ƒ› ’•› Š‹ƒ–”‹  †‹•‘”†‡”ǡ Ž‹‹ ƒŽ •‹‰‹ˆ‹ ƒ– ‡†‹ ƒŽ †‹•‡ƒ•‡ǡ ’ƒ•– Š‡ƒ† ‹Œ—”› ™‹–Š Ž‘•• ‘ˆ ‘• ‹‘—•‡•• ε ͷ ‹ǡ ƒ† —•‡ ‘ˆ ‡†‹ ƒ–‹‘ǤŽŽ’ƒ”–‹ ‹’ƒ–•’”‘˜‹†‡†™”‹––‡‹ˆ‘”‡† ‘•‡–’”‹‘”–‘’ƒ”–‹ ‹’ƒ–‹‘‹. . ͳ—–‘ˆˆ• ‘”‡•ˆ‘”–Š‡•‡‰”‘—’•™‡”‡„ƒ•‡†‘–Š‡Ž‘™‡”–Š‹”†ƒ†–Š‡—’’‡”–Š‹”†‘ˆ–Š‡†‹•–”‹„—–‹‘‘ˆ. 

(18) • ‘”‡•ȋ”ƒ‰‡ͻǦʹͺǡαͳͺǤͷǡα͵Ǥ͸Ȍ‹ƒ•ƒ’Ž‡‘ˆͳͷ͵ƒŽ‡•–—†‡–•Ǥ . ͳ͵ͷ.

(19) Chapter7. –Š‡ •–—†›ǡ ™Š‹ Š ™ƒ• ƒ’’”‘˜‡† „› –Š‡ ‡†‹ ƒŽ –Š‹ ƒŽ ‘‹––‡‡ ‘ˆ –Š‡ ‡‹†‡ ‹˜‡”•‹–›‡†‹ ƒŽ‡–‡”Ǥ  Procedure Š‡ ’ƒ”–‹ ‹’ƒ–• ™‡”‡ ‰‹˜‡ ƒ ͷͲ ‰ Š›†”‘ ‘”–‹•‘‡ ‘” ’Žƒ ‡„‘ ƒ’•—Ž‡ ‹ ƒ †‘—„Ž‡Ǧ„Ž‹†ǡ ™‹–Š‹Ǧ•—„Œ‡ – ”‘••‘˜‡” †‡•‹‰Ǥ Š‡ ‘”†‡” ‘ˆ ‘”–‹•‘Ž ‘” ’Žƒ ‡„‘ ƒ†‹‹•–”ƒ–‹‘™ƒ•”ƒ†‘ƒ†„ƒŽƒ ‡†™‹–Š‹–Š‡Š‹‰Šƒ†Ž‘™

(20) ‰”‘—’•ǤŠ‡–™‘ ‡š’‡”‹‡–ƒŽ•‡••‹‘•™‡”‡‘‡™‡‡ƒ’ƒ”–Ǥ–Š‡†ƒ›•‘ˆ–‡•–‹‰ǡ’ƒ”–‹ ‹’ƒ–•ƒ””‹˜‡† ƒ– –Š‡ Žƒ„‘”ƒ–‘”› ™Š‡”‡ǡ ƒˆ–‡” ƒ •Š‘”– ‹–”‘†— –‹‘ǡ †”—‰ ƒ†‹‹•–”ƒ–‹‘ –‘‘ ’Žƒ ‡ ƒ– ͳʹǤ͵Ͳ ‘” ͳͶǤ͵Ͳ Šǡ ˆ‘ŽŽ‘™‡† „› ƒ ”‡•–‹‰ ’‡”‹‘† ‘ˆ ‘‡ Š‘—” –‘ ƒŽŽ‘™ ˆ‘” –Š‡ ‘”–‹•‘Ž –‘ –ƒ‡ ‡ˆˆ‡ –Ǥʹ —”‹‰ –Š‹• ’‡”‹‘†ǡ ’ƒ”–‹ ‹’ƒ–• ‘’Ž‡–‡† “—‡•–‹‘ƒ‹”‡• ƒ† –Š‡ ‡Ž‡ –”‘†‡• ˆ‘” –Š‡   ‡ƒ•—”‡‡–• ™‡”‡ ’Žƒ ‡†Ǥ —„•‡“—‡–Ž›ǡ –Š‡ ‡š’‡”‹‡– •–ƒ”–‡†™‹–Š–Š‡‡ƒ•—”‡‡–‘ˆ”‡•–‹‰•–ƒ–‡ ǡˆ‘ŽŽ‘™‡†„›ƒ—„‡”‘ˆƒ††‹–‹‘ƒŽ ‘‰‹–‹˜‡ –‡•–• ‘ˆ ™Š‹ Š –Š‡ ”‡•—Ž–• ™‹ŽŽ „‡ ”‡’‘”–‡† ‡Ž•‡™Š‡”‡ ȋƒ ‡‡” ‡–ƒŽǤǡ ʹͲͲ͹ȌǤ ‡•–‹‰•–ƒ–‡ ™ƒ•‡ƒ•—”‡†‹ƒ•‡”‹‡•‘ˆ‡‹‰Š–ͳǦ‹—–‡”‡ ‘”†‹‰’‡”‹‘†•ǡ™Š‹Ž‡ –Š‡’ƒ”–‹ ‹’ƒ–••ƒ–“—‹‡–Ž›™‹–Š‡›‡•‘’‡‡†ƒ† Ž‘•‡†‹ ‘—–‡”„ƒŽƒ ‡†–”‹ƒŽ•ȋ‹Ǥ‡Ǥǡ ‘”ȌǤ‹–Š‡›‡•‘’‡‡†ǡ’ƒ”–‹ ‹’ƒ–•™‡”‡‹•–”— –‡†–‘Ž‘‘ƒ–ƒ ˆ‹šƒ–‹‘’‘‹–‹ˆ”‘–‘ˆ–Š‡Ǥƒ”–‹ ‹’ƒ–••ƒ–‹ƒ†‹Ž›Ž‹–ǡƒ‹”Ǧ ‘†‹–‹‘‡†ƒ†•‘—†Ǧ ƒ––‡—ƒ–‡† ”‘‘ǡ ™Š‹Ž‡ –Š‡ ‡š’‡”‹‡–‡” •ƒ– ‹ ƒ ƒ†Œƒ ‡– ”‘‘ ™Š‡”‡ –Š‡   ƒ’’ƒ”ƒ–—•™ƒ•Ž‘ ƒ–‡†Ǥ  Psychophysiologicaldatareductionandanalysis Š‡‡Ž‡ –”‘‡ ‡’ŠƒŽ‘‰”ƒȋ Ȍ™ƒ•”‡ ‘”†‡†ˆ”‘ͳͻ• ƒŽ’Ž‘ ƒ–‹‘•ƒ ‘”†‹‰ –‘ –Š‡ ‹–‡”ƒ–‹‘ƒŽ ͳͲǦʹͲ •›•–‡ ƒ† ”‡ˆ‡””‡† ‘ǦŽ‹‡ –‘ ͵ȀͶǤ ‡”–‹ ƒŽ ‡Ž‡ –”‘Ǧ ‘ —Ž‘‰”ƒ ȋ Ȍ ™ƒ• ”‡ ‘”†‡† „‹’‘Žƒ”Ž› ˆ”‘ –Š‡ •—’”ƒ‘”„‹–ƒŽ ƒ† –Š‡ ‹ˆ”ƒ‘”„‹–ƒŽ ”‹†‰‡‘ˆ–Š‡”‹‰Š–‡›‡ǡƒ†Š‘”‹œ‘–ƒŽ ˆ”‘–Š‡‘—–‡” ƒ–Š‹‘ˆ„‘–Š‡›‡•ǤŠ‡‰”‘—† ‡Ž‡ –”‘†‡™ƒ•Ž‘ ƒ–‡†ƒ– ’œǤ ‹’‡†ƒ ‡•™‡”‡‡’–„‡Ž‘™ͷȳǤŠ‡ ƒ†  •‹‰ƒŽ• ™‡”‡ †‹‰‹–‹œ‡† ƒ– ͷͲͲ œǤ ‹‰ƒŽ• ™‡”‡ ’”‘ ‡••‡† ‘ˆˆŽ‹‡ —•‹‰ ”ƒ‹ ‹•‹‘ ƒŽ›œ‡”•‘ˆ–™ƒ”‡ȋ˜‡”•‹‘ͳǤͲͷǡ”ƒ‹”‘†— –• „ ǡͳͻͻͺǦʹͲͲͶȌǤ . ʹ‘”–‹•‘Ž ƒ”‡ƒ†‹Ž› ”‘••–Š‡„Ž‘‘†Ǧ„”ƒ‹„ƒ””‹‡”ȋ•‡‡‡Ǥ‰Ǥ ‡”„‡”–‡–ƒŽǤǡʹͲͲ͸ˆ‘”ƒ”‡˜‹‡™Ȍǡƒ† ‘”–‹•‘Ž. ƒ†‹‹•–”ƒ–‹‘Šƒ•„‡‡•Š‘™–‘•‹‰‹ˆ‹ ƒ–Ž›ƒˆˆ‡ – ‘‰‹–‹˜‡ƒ†‡‘–‹‘ƒŽ’”‘ ‡••‡•ȋ‡Ǥ‰Ǥ‹”• Š„ƒ— ‡–ƒŽǤǡͳͻͻ͸Ǣ—’‹‡‡–ƒŽǤǡͳͻͻͻǢ˜ƒ‡‡”‡–ƒŽǤǡʹͲͲ͹Ǣ—–ƒ‡–ƒŽǤǡʹͲͲ͹Ǣ‡—–‡”ǡʹͲͲʹȌƒ•™‡ŽŽƒ•”‡•–‹‰ •–ƒ–‡ ȋ‡Ǥ‰Ǥ‘’•‡–ƒŽǤǡʹͲͲͷǢʹͲͲ͸Ȍˆ”‘‘‡Š‘—”ƒˆ–‡”ƒ†‹‹•–”ƒ–‹‘ǡ™Š‡ ‘”–‹•‘ŽŽ‡˜‡Ž•”‡ƒ Š–Š‡‹” ƒš‹—ȋ‡Ǥ‰Ǥ‡—–‡”ǡʹͲͲʹǢ•‡‡ƒŽ•‘˜ƒ‡‡”‡–ƒŽǤǡʹͲͲ͹ȌǤ. ͳ͵͸.

(21) Cortisolenhancesdeltabetacorrelation. ‹‰ƒŽ• ™‡”‡ ”‡Ǧ”‡ˆ‡”‡ ‡† –‘ ƒ ƒ˜‡”ƒ‰‡Ǧ‡ƒ”• ”‡ˆ‡”‡ ‡ ƒ† ˆ‹Ž–‡”‡† ™‹–Š —––‡”™‘”–Š‡”‘Šƒ•‡ ‹Ž–‡”•ȋŽ‘™ —–‘ˆˆǣͲǤͳ œȋͳʹ†Ȁ‘ –ȌǡŠ‹‰Š —–‘ˆˆǣͳͲͲ œȋͳʹ †Ȁ‘ –Ȍǡ‘– Šˆ‹Ž–‡”ǣ͸Ͳ œȌǤ—„•‡“—‡–Ž›ǡ–Š‡†ƒ–ƒ‘ˆ‡ƒ ŠͳǦ‹—–‡”‡ ‘”†‹‰’‡”‹‘† ™‡”‡•‡‰‡–‡†‹–‘ͳǤͲʹͶ•‡ ‘†•‡‰‡–•ǡ™‹–ŠͷͲΨ‘˜‡”Žƒ’Ǥ‘—‰Šƒ”–‹ˆƒ –”‡Œ‡ –‹‘ ȋΪȀǦ ʹͲͲ ρȌǡ ˆ‘ŽŽ‘™‡† „› ƒ—–‘ƒ–‹  ‘ —Žƒ” ‘””‡ –‹‘ —•‹‰ ƒ •–ƒ†ƒ”† ’”‘ ‡†—”‡ ȋ ”ƒ––‘ ‡– ƒŽǤǡ ͳͻͺ͵Ȍ ƒ† ƒ—–‘ƒ–‹  ƒ”–‹ˆƒ – ”‡Œ‡ –‹‘ ȋΪȀǦ ͳͲͲ ρǡ Ž‘™‡•– ƒŽŽ‘™‡† ƒ –‹˜‹–› ͲǤͷ ρ ˆ‘” ͳͲͲ •Ȍ ™‡”‡ ’‡”ˆ‘”‡† ‘ –Š‡•‡ •‡‰‡–•Ǥ Š‡ †‡•‹‰ƒ–‹‘ ‘ˆ ƒ ƒ”–‹ˆƒ –‹‘‡‘ˆ–Š‡Ž‡ƒ†•”‡•—Ž–‡†‹–Š‡”‡‘˜ƒŽ‘ˆ–Šƒ–‡’‘ Šˆ‘”ƒŽŽ Šƒ‡Ž•‹‘”†‡” –‘ ‡•—”‡ –Šƒ– –Š‡ ”‡ƒ‹‹‰ †ƒ–ƒ ™‡”‡ ‹†‡–‹ ƒŽ ˆ‘” ƒŽŽ •‹–‡• ‹ –‹‡Ǥ  ƒ•– ‘—”‹‡” ”ƒ•ˆ‘”ȋ ǡˆ—ŽŽ•’‡ –”—‡–Š‘†ǡ ƒ‹‰™‹†‘™‘ˆͳͲΨŽ‡‰–ŠȌ™ƒ•ƒ’’Ž‹‡†–‘ Š—• ‘ˆ ƒ”–‹ˆƒ –Ǧˆ”‡‡ †ƒ–ƒ –‘ ‘„–ƒ‹ ‡•–‹ƒ–‡• ‘ˆ •’‡ –”ƒŽ ’‘™‡” †‡•‹–› ȋρ;Ȁ œȌǤ ’‡ –”ƒŽ’‘™‡”†‡•‹–›˜ƒŽ—‡•ˆ‘”‡ƒ Š‡Ž‡ –”‘†‡™‡”‡ƒ˜‡”ƒ‰‡†ƒ ”‘••ƒŽŽ‡’‘ Š•™‹–Š‹ ƒ •‹‰Ž‡ „ƒ•‡Ž‹‡ ƒ† ƒŽ —Žƒ–‡† ˆ‘” –Š‡ †‡Ž–ƒ ȋͳǦ͵ œȌǡ ƒ† „‡–ƒ ȋͳͶǦ͵Ͳ œȌ ˆ”‡“—‡ › „ƒ†•Ǥ   ƒ–—”ƒŽ Ž‘‰ –”ƒ•ˆ‘”ƒ–‹‘ ȋŽȌ ™ƒ• ’‡”ˆ‘”‡† ‘ –Š‡•‡ ˜ƒŽ—‡• –‘ ‘”ƒŽ‹œ‡ –Š‡†‹•–”‹„—–‹‘ǤŠ‡†ƒ–ƒˆ”‘‘‡’ƒ”–‹ ‹’ƒ–™‡”‡‡š Ž—†‡†ˆ”‘–Š‡ƒƒŽ›•‡•„‡ ƒ—•‡ ‘ˆ†‡˜‹ƒ–Ž†‡Ž–ƒ’‘™‡”†‡•‹–›‹„‘–Š–Š‡’Žƒ ‡„‘ƒ† ‘”–‹•‘Ž ‘†‹–‹‘ȋZǦ• ‘”‡ε ͵Ǥͷ‹„‘–Š ‘†‹–‹‘•ȌǤ ‹ ‡ƒ•’‡ ‹ˆ‹ ƒ‹‘ˆ–Š‡’”‡•‡–•–—†›™ƒ•–‘‡š–‡†–Š‡ˆ‹†‹‰•‘ˆ’”‡˜‹‘—• •–—†‹‡•ǡ™‡ˆ‘ —•‡†‘—”’”‹ƒ”›ƒƒŽ›•‡•‘–Š‡‹†ˆ”‘–ƒŽȋ œȌ‡Ž‡ –”‘†‡ǡˆ‘”™Š‹ Š–Š‡ ‡ˆˆ‡ –• ‘ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ Šƒ˜‡ „‡‡ ”‡’‘”–‡† –‘ „‡ •’‡ ‹ˆ‹ ƒŽŽ› ’”‘‘— ‡† ȋ Š—––‡” Ƭ ƒ ‘ǡ ʹͲͲͶǡ ʹͲͲͷȌǤ ‘™‡˜‡”ǡ ‹ ‘”†‡” –‘ ‡š’Ž‘”‡ –Š‡ –‘’‘‰”ƒ’Š‹  †‹•–”‹„—–‹‘‘ˆ–Š‡‡ˆˆ‡ –•‘ˆ ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘ƒ†‰”‘—’†‹ˆˆ‡”‡ ‡•‹†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ǡ ™‡ ’‡”ˆ‘”‡† ƒ††‹–‹‘ƒŽ ƒƒŽ›•‡• ‹ Ž—†‹‰ ‘”‡ Žƒ–‡”ƒŽ ƒ† ’‘•–‡”‹‘” ‡Ž‡ –”‘†‡•ȋ ͵ǡ Ͷǡ͵ǡœǡͶǡ͵ǡœǡͶȌǤ –ƒ–‹•–‹ ƒŽ ƒƒŽ›•‡• ™‡”‡ ’‡”ˆ‘”‡† ‘ –Š‡ ‡ƒ”•‘ ‘””‡Žƒ–‹‘ „‡–™‡‡ Ž ƒ˜‡”ƒ‰‡ ’‘™‡” †‡•‹–› ‹ –Š‡ †‡Ž–ƒ ƒ† „‡–ƒ ˆ”‡“—‡ › „ƒ†• ƒ ”‘•• ƒŽŽ ”‡ ‘”†‹‰ ’‡”‹‘†•ȋ‹Ǥ‡Ǥǡ–Š‡†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘Ȍǡƒ–‡ƒ Š‡Ž‡ –”‘†‡‹‡ƒ Š ‘†‹–‹‘Ǥ‘–‡•–ˆ‘” •‹‰‹ˆ‹ ƒ– †‹ˆˆ‡”‡ ‡• „‡–™‡‡ ‘””‡Žƒ–‹‘•ǡ ™‡ —•‡† ‹•Š‡”ǯ• r –‘ r’ –”ƒ•ˆ‘”ƒ–‹‘ –‘ ‘”ƒŽ‹œ‡–Š‡†‹•–”‹„—–‹‘‘ˆ ‘””‡Žƒ–‹‘ ‘‡ˆˆ‹ ‹‡–•ǡ™Š‹ ŠƒŽŽ‘™•–Š‡—•‡‘ˆƒZǦ–‡•––‘ ‘’ƒ”‡–Š‡ ‘””‡Žƒ–‹‘•Ǥ‘–‡•––Š‡‡ˆˆ‡ –‘ˆ ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘™‡ ƒŽ —Žƒ–‡†ƒZǦ • ‘”‡ˆ‘”‘Ǧ‹†‡’‡†‡–‰”‘—’•ǡƒ†–‘–‡•–ˆ‘”‰”‘—’†‹ˆˆ‡”‡ ‡•™‡ ƒŽ —Žƒ–‡†ƒ ZǦ • ‘”‡ˆ‘”‹†‡’‡†‡–‰”‘—’•ȋ•‡‡Žƒ”Ǧƒ”–‡”ǡͳͻͻ͹ȌǤ ‹˜‡‘—”•’‡ ‹ˆ‹ †‹”‡ –‹‘ƒŽ. ͳ͵͹.

(22) Chapter7. Š›’‘–Š‡•‡• ˆ‘” ‹ ”‡ƒ•‡† †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘• ƒ••‘ ‹ƒ–‡† ™‹–Š ‘”–‹•‘Ž ƒ† –”ƒ‹– ‹Š‹„‹–‹‘ǡ ‘†‹–‹‘ƒ†‰”‘—’‡ˆˆ‡ –•™‡”‡–‡•–‡†™‹–Šƒ‘‡Ǧ–ƒ‹Ž‡†ƒŽ’Šƒ‘ˆǤͲͷǤ  Salivarycortisolmeasures ‘ ˜‡”‹ˆ› –Š‡ ‡ˆˆ‡ – ‘ˆ ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ƒ† –‘ Š‡  ˆ‘” ’‘••‹„Ž‡ †‹ˆˆ‡”‡ ‡•‹„ƒ•‡Ž‹‡ ‘”–‹•‘Žǡ•ƒŽ‹˜ƒ•ƒ’Ž‡•™‡”‡‘„–ƒ‹‡†—•‹‰ƒŽ‹˜‡––‡ ‘ŽŽ‡ –‹‘ †‡˜‹ ‡• ȋƒ”•–‡†–ǡ ‘‡Ž•†‘”ˆǡ ‡”ƒ›ȌǤ ƒ’Ž‡• ™‡”‡ ‘„–ƒ‹‡† „‡ˆ‘”‡ ƒ’•—Ž‡ ‹–ƒ‡ ƒ† ƒ– –Š‡ •–ƒ”– ‘ˆ –Š‡   ”‡ ‘”†‹‰ ȋ‘‡ Š‘—” ƒˆ–‡” ƒ’•—Ž‡ ‹‰‡•–‹‘ȌǤ ‹‘ Š‡‹ ƒŽ ƒƒŽ›•‹• ‘ˆ ˆ”‡‡ ‘”–‹•‘Ž ‹ •ƒŽ‹˜ƒ ™ƒ• ’‡”ˆ‘”‡† —•‹‰ ƒ ‘’‡–‹–‹˜‡ ‡Ž‡ –”‘ Š‡‹Ž—‹‡• ‡ ‡ ‹—‘ƒ••ƒ› ȋ

(23) ǡ Ž‡ •›• ʹͲͳͲǡ ‘ Š‡ ‹ƒ‰‘•–‹ •Ȍǡ ƒ• †‡• ”‹„‡†‡Ž•‡™Š‡”‡ȋƒ‡‡–ƒŽǤǡʹͲͲ͵ȌǤ. Results Salivarycortisol ƒŽ‹˜ƒ”› ‘”–‹•‘Ž ȋ‘ŽȀȌ ‡ƒ•—”‡• ™‡”‡ •‡™‡† ƒ† –Š‡”‡ˆ‘”‡ ƒ–—”ƒŽ Ž‘‰ –”ƒ•ˆ‘”‡† „‡ˆ‘”‡ •–ƒ–‹•–‹ ƒŽ ƒƒŽ›•‹•Ǥ • ‡š’‡ –‡†ǡ —„‘—† Ž‡˜‡Ž• ‘ˆ ‘”–‹•‘Ž †‹† ‘– †‹ˆˆ‡”„‡–™‡‡ ‘†‹–‹‘•„‡ˆ‘”‡ ƒ’•—Ž‡‹–ƒ‡ȋ’Žƒ ‡„‘ǣMαͻǤͳǡSDα͵ǤͲǢ ‘”–‹•‘ŽǣMα ͻǤͶǡSDαʹǤͺǢtȋ͵͹ȌαǦͲǤ͹ͶǡpαǤͶ͹Ȍǡ„—–™‡”‡•‹‰‹ˆ‹ ƒ–Ž›‹ ”‡ƒ•‡†ȋtȋ͵͹ȌαǦͳͺǤ͸ͻǡp δ ǤͲͲͳȌ ‘‡ Š‘—” ƒˆ–‡” ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ȋM α ͳ͹͵ǤͶǡ SD α ͳͶʹǤ͵Ȍ ‘’ƒ”‡† –‘ ’Žƒ ‡„‘ ȋM α ͸Ǥͺǡ SD α ͳǤ͹ȌǤ Š‡”‡ ™‡”‡ ‘ •‹‰‹ˆ‹ ƒ– †‹ˆˆ‡”‡ ‡• ‹ •ƒŽ‹˜ƒ”› ‘”–‹•‘Ž ˜ƒŽ—‡•„‡–™‡‡–Š‡Ž‘™

(24) ƒ†Š‹‰Š

(25) ’ƒ”–‹ ‹’ƒ–•ȋƒŽŽpεǤʹͲȌǤ  Deltabetacorrelation Effectofcortisoladministration ‹”•–ǡ–‘–‡•––Š‡Š›’‘–Š‡•‹•–Šƒ– ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘ ƒ‡Šƒ ‡‹†ˆ”‘–ƒŽ †‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰ǡ ™‡ ƒŽ —Žƒ–‡† –Š‡ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ƒ– œ ‡Ž‡ –”‘†‡ ƒˆ–‡” ’Žƒ ‡„‘ƒ† ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘ˆ‘”ƒŽŽ’ƒ”–‹ ‹’ƒ–•ȋ•‡‡ƒ„Ž‡͹ǤͳȌǤ

(26) Ž‹‡™‹–Š‘—” ‡š’‡ –ƒ–‹‘•ǡ ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ”‡•—Ž–‡† ‹ ƒ ‡ƒ”Ǧ•‹‰‹ˆ‹ ƒ– ‹ ”‡ƒ•‡ ‹ –Š‡ ‹†ˆ”‘–ƒŽ†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ‘’ƒ”‡†–‘’Žƒ ‡„‘ȋZαǦͳǤͷ͹ǡpαǤͲͷͺȌǤ š–‡†‡†ƒƒŽ›•‡•‹ Ž—†‹‰‘”‡Žƒ–‡”ƒŽƒ†’‘•–‡”‹‘”‡Ž‡ –”‘†‡•ȋ ͵ǡ Ͷǡ͵ǡͶǡ œǡ͵ǡͶǡƒ†œȌ•Š‘™‡†–Šƒ– ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘–‡†‡†–‘‹ ”‡ƒ•‡–Š‡†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘‘ƒŽŽ‡Ž‡ –”‘†‡•ȋ‡š ‡’–ˆ‘”ƒ†‡ ”‡ƒ•‡ƒ– ͶȌǡ„—–„‡•‹†‡•–Š‡‹†ˆ”‘–ƒŽ  ͳ͵ͺ.

(27) Cortisolenhancesdeltabetacorrelation. Table7.1.‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ȋ‡ƒ”•‘ ‘””‡Žƒ–‹‘„‡–™‡‡‡ƒŽ†‡Ž–ƒ’‘™‡”†‡•‹–›ƒ†‡ƒŽ „‡–ƒ ’‘™‡” †‡•‹–› ƒ– œ ‡Ž‡ –”‘†‡Ȍ ƒ† ‡ƒ ȋȌ †‡Ž–ƒ ƒ† „‡–ƒ ƒ –‹˜‹–› ȋŽ ’‘™‡” †‡•‹–› ƒ– œ ‡Ž‡ –”‘†‡Ȍ ƒˆ–‡” ’Žƒ ‡„‘ ƒ† ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ˆ‘” ƒŽŽ •—„Œ‡ –• ƒ† ˆ‘” –Š‡ Ž‘™ 

(28)  ƒ† Š‹‰Š 

(29)  •—„‰”‘—’•Ǥ  Žƒ ‡„‘ ‘”–‹•‘Ž ‡ƒ•—”‡ ŽŽ  

(30)  

(31)  ŽŽ 

(32)   

(33)  ȋα͵ͻȌ ȋαͳͻȌ ȋαʹͲȌ ȋα͵ͻȌ ȋαͳͻȌ ȋαʹͲȌ ‡Ž–ƒǦ„‡–ƒ αǤʹͻ  αǤͲͺ αǤͷͲȗ αǤͷͳȗȗ αǤ͵ͳ  αǤ͹Ͳȗȗ ‘””‡Žƒ–‹‘ †‡Ž–ƒ ʹǤͷʹȋͲǤ͵Ȍ  ʹǤͷͷȋͲǤ͵Ȍ ʹǤͶͺȋͲǤʹȌ ʹǤͶͻȋͲǤʹȌ ʹǤͷͳȋͲǤʹȌ  ʹǤͶ͹ȋͲǤ͵Ȍ ’‘™‡” „‡–ƒ ǦǤͻ͹ȋͲǤͶȌ  ǦǤͻͶȋͲǤͶȌ ǦǤͻͻȋͲǤͶȌ ǦǤͻͻȋͲǤͷȌ ǦǤͻͺȋͲǤͷȌ  ǦǤͲͳȋͲǤͷȌ ’‘™‡” ȗ’δǤͲͷǡȗȗ’δǤͲͲͳ. . ȋ œȌ ‡Ž‡ –”‘†‡ –Š‹• ‡ˆˆ‡ – ‘Ž› ƒ’’”‘ƒ Š‡† •‹‰‹ˆ‹ ƒ ‡ ƒ– ͵ ȋZ α ǦͳǤ͵ͷǡ p α ǤͲͻȌ ȋ•‡‡ ‹‰—”‡͹Ǥͳǡ’ƒ‡ŽȌǤ

(34) –‡”‡•–‹‰Ž›ǡ ‹ ‘–”ƒ•– –‘ –Š‡ ‡ˆˆ‡ –• ‘ –Š‡ correlation „‡–™‡‡ ‹†ˆ”‘–ƒŽ †‡Ž–ƒ ƒ† „‡–ƒ ’‘™‡”ǡ  ’ƒ‹”‡† •ƒ’Ž‡• tǦ–‡•–• •Š‘™‡† ‘ †‹ˆˆ‡”‡ ‡• „‡–™‡‡ –Š‡ ’Žƒ ‡„‘ƒ† ‘”–‹•‘Ž ‘†‹–‹‘•‹‡‹–Š‡”‡ƒŽ†‡Ž–ƒ’‘™‡”ȋtȋ͵ͺȌαͲǤͺͲǡpαǤͶ͵Ȍ‘” ‡ƒŽ„‡–ƒ’‘™‡”ȋtȋ͵ͺȌαͲǤͻͶǡpαǤ͵͸Ȍƒ– œȋ•‡‡ƒ„Ž‡͹ǤͳȌǡ‘”ƒ–ƒ›‘ˆ–Š‡‘–Š‡” ‡Ž‡ –”‘†‡•Ǥ  Behavioralinhibition ‘–‡•––Š‡Š›’‘–Š‡•‹•–Šƒ–Š‹‰Š„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘‹•ƒ••‘ ‹ƒ–‡†™‹–Š‹ ”‡ƒ•‡† ‹†ˆ”‘–ƒŽ†‡Ž–ƒǦ„‡–ƒ ‘—’Ž‹‰ǡ–Š‡†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ƒ– œ‡Ž‡ –”‘†‡™ƒ• ƒŽ —Žƒ–‡† •‡’ƒ”ƒ–‡Ž›ˆ‘”Š‹‰Šƒ†Ž‘™

(35) Ǧ‰”‘—’•‹–Š‡’Žƒ ‡„‘ƒ† ‘”–‹•‘Ž ‘†‹–‹‘•ȋ•‡‡ƒ„Ž‡ ͹Ǥͳ ƒ† ‹‰—”‡ ͹ǤʹȌǤ • ‡š’‡ –‡†ǡ –Š‡ ‹†ˆ”‘–ƒŽ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ‹ –Š‡ ’Žƒ ‡„‘ ‘†‹–‹‘ ™ƒ• •‹‰‹ˆ‹ ƒ– ‹ –Š‡ Š‹‰Š 

(36)  ‰”‘—’ǡ „—– ‘– –Š‡ Ž‘™ 

(37)  ‰”‘—’ ȋ ”‘—’ †‹ˆˆ‡”‡ ‡ǣ Z α Ǧ ͳǤ͵͵ǡ p α ǤͲͻȌǤ Ž–Š‘—‰Š ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ”‡•—Ž–‡† ‹ ƒ ‰‡‡”ƒŽ ‹ ”‡ƒ•‡ ‹ ‹†ˆ”‘–ƒŽ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ‘’ƒ”‡† –‘ ’Žƒ ‡„‘ ȋ•‡‡ ƒ„‘˜‡Ȍǡ –Š‹• ‘””‡Žƒ–‹‘”‡ƒ‹‡†‘Ǧ•‹‰‹ˆ‹ ƒ–ƒˆ–‡” ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘‹–Š‡Ž‘™

(38) ‰”‘—’ ȋ•‡‡ ƒ„Ž‡ ͹ǤͳȌǤ Š‡ ‰”‘—’ †‹ˆˆ‡”‡ ‡ ™ƒ• „‘”†‡”Ž‹‡ •‹‰‹ˆ‹ ƒ– ƒˆ–‡” ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ȋZαǦͳǤͷ͹ǡpαǤͲͷͺȌǤ

(39) Ž‹‡™‹–Š–Š‡ˆ‹†‹‰•‘ œǡ”‡•—Ž–•‘ˆ–Š‡‡š–‡†‡†ƒƒŽ›•‡•ȋ‹ Ž—†‹‰ ͵ǡ Ͷǡ ͵ǡͶǡœǡ͵ǡͶǡƒ†œȌ•Š‘™‡†•‹‰‹ˆ‹ ƒ–†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘•ˆ‘”Š‹‰Š

(40) ǡ„—–‘– ˆ‘” Ž‘™ 

(41)  ’ƒ”–‹ ‹’ƒ–• ‘ ƒŽŽ ‡Ž‡ –”‘†‡• ‹ –Š‡ ‘”–‹•‘Ž ‘†‹–‹‘ǡ ƒ† ‘ ƒŽ‘•– ƒŽŽ ‡Ž‡ –”‘†‡•ȋ‡š ‡’–ˆ‘”ƒŽ‘™‡” ‘””‡Žƒ–‹‘ƒ– ͵ǡ Ͷǡƒ†ͶȌ‹–Š‡’Žƒ ‡„‘ ‘†‹–‹‘ȋ•‡‡ ‹‰—”‡͹ǤͳȌǤ ‘™‡˜‡”ǡ„‡•‹†‡•–Š‡‡ˆˆ‡ –ƒ– œǡ‹„‘–Š ‘†‹–‹‘•–Š‡‰”‘—’†‹ˆˆ‡”‡ ‡. ͳ͵ͻ.

(42) Chapter7. . (A). All subjects: placebo vs. cortisol. 0.8. Delta-beta correlation. 0.7 0.6. *. *. placebo cortisol. 0.5 0.4 0.3 0.2 0.1 0.0 Fz. (B) Delta-beta correlation. 0.8 0.7. F3. F4. Cz. C3. C4. Pz. P3. P4. Placebo: low BIS vs. high BIS. *. Low BIS High BIS. *. 0.6 0.5 0.4 0.3 0.2 0.1 0.0 -0.1 Fz. (C) Delta-beta correlation. 0.8 0.7. F3. F4. Cz. C3. C4. Pz. P3. Cortisol: low BIS vs. high BIS. *. P4. Low BIS High BIS. **. 0.6 0.5 0.4 0.3 0.2 0.1 0.0 -0.1 Fz. F3. F4. Cz. C3. C4. Pz. P3. P4.  Figure7.1.‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘•ȋ‡ƒ”•‘ ‘””‡Žƒ–‹‘„‡–™‡‡‡ƒŽ†‡Ž–ƒ’‘™‡”†‡•‹–›ƒ†‡ƒ Ž „‡–ƒ ’‘™‡” †‡•‹–›Ȍ „› ‡Ž‡ –”‘†‡ •‹–‡ ˆ‘” ȋȌ ƒŽŽ ’ƒ”–‹ ‹’ƒ–• ȋ α ͵ͻȌ ƒˆ–‡” ’Žƒ ‡„‘ ƒ† ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ǡȋȌŽ‘™

(43) ȋαͳͻȌƒ†Š‹‰Š

(44) ȋαʹͲȌ’ƒ”–‹ ‹’ƒ–•ƒˆ–‡”’Žƒ ‡„‘ƒ†‹‹•–”ƒ–‹‘ǡƒ† ȋȌŽ‘™

(45) ƒ†Š‹‰Š

(46) ’ƒ”–‹ ‹’ƒ–•ƒˆ–‡” ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘ǤȗpδǤͳͲȗȗpδǤͲͷȋͳǦ–ƒ‹Ž‡†Ȍ. ͳͶͲ.

(47) Cortisolenhancesdeltabetacorrelation. Low BIS placebo (n = 19). - 0,5. - 1,0. - 1,5. r = 0.08, p = .74 - 2,0. 1,5. 2,0. 2,5. 3,0. High BIS placebo (n = 20). 0,0. ln beta power density at Fz (μV²/Hz). ln beta power density at Fz (μV²/Hz). 0,0. - 0,5. - 1,0. - 1,5. r = 0.50, p = .03 - 2,0. 3,5. 1,5. 0,0. - 0,5. - 1,0. - 1,5. r = 0.31, p = .20. -2,0. 1,5. 2,0. 2,5. 3,0. ln delta power density at Fz (μV²/Hz). 3,5. ln beta power density at Fz (μV²/Hz). ln beta power density at Fz (μV²/Hz). Low BIS cortisol (n = 19). 0,5. 2,0. 2,5. 3,0. 3,5. ln delta power density at Fz (μV²/Hz). ln delta power density at Fz (μV²/Hz). High BIS cortisol (n = 20). 0,0. -0,5. -1,0. - 1,5. r = 0.70, p = .001. - 2,0 1,5. 2,0. 2,5. 3,0. 3,5. ln delta power density at Fz (μV²/Hz). . Figure7.2.‹‰‹ˆ‹ ƒ–‹†ˆ”‘–ƒŽ†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘‹Š‹‰Š

(48) ’ƒ”–‹ ‹’ƒ–•ȋ”‹‰Š–Ȍǡ„—–‘–‹Ž‘™

(49)  ’ƒ”–‹ ‹’ƒ–•ȋŽ‡ˆ–Ȍƒˆ–‡”’Žƒ ‡„‘ƒ† ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘Ǥ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘ȋ„‘––‘Ȍ”‡•—Ž–‡†‹ƒ ‰‡‡”ƒŽ‹ ”‡ƒ•‡‹†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ‘’ƒ”‡†–‘’Žƒ ‡„‘ȋ–‘’Ȍˆ‘”ƒŽŽ’ƒ”–‹ ‹’ƒ–•Ǥ. . ‘Ž›ƒ’’”‘ƒ Š‡†•‹‰‹ˆ‹ ƒ ‡ƒ–œȋ’Žƒ ‡„‘ǣZαǦͳǤͶͻǡpαǤͲ͹Ǣ ‘”–‹•‘ŽǣZαǦʹǤ͵ͺǡpδǤͲͳȌ ȋ•‡‡ ‹‰—”‡͹Ǥͳǡ’ƒ‡Ž•ƒ†ȌǤ ‹‰Š ƒ† Ž‘™ 

(50)  ’ƒ”–‹ ‹’ƒ–• †‹† ‘– †‹ˆˆ‡” ‹ ‡‹–Š‡” ‡ƒ Ž †‡Ž–ƒ ’‘™‡” ȋ’Žƒ ‡„‘ǣtȋ͵͹ȌαͲǤͺ͸ǡpαǤ͵ͻǢ ‘”–‹•‘Žǣtȋ͵͹ȌαͲǤͷ͹ǡpαǤͷ͹Ȍ‘”‡ƒŽ„‡–ƒ’‘™‡” ȋ’Žƒ ‡„‘ǣtȋ͵͹ȌαͲǤͶͲǡpαǤ͸ͻǢ ‘”–‹•‘Žǣtȋ͵͹ȌαͲǤͳ͹ǡpαǤͺ͹Ȍƒ– œȋ•‡‡ƒ„Ž‡͹ǤͳȌǡ‘”ƒ– ƒ›‘ˆ–Š‡‘–Š‡”‡Ž‡ –”‘†‡•Ǥ. Discussion  Š‹• •–—†› •Š‘™• –Šƒ– ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ –‡†‡† –‘ ‹ ”‡ƒ•‡ –Š‡ ‘””‡Žƒ–‹‘ „‡–™‡‡‹†ˆ”‘–ƒŽȀ ‡–”ƒŽ†‡Ž–ƒƒ†„‡–ƒ•’‡ –”ƒŽ’‘™‡”‹Š‡ƒŽ–Š›ƒŽ‡’ƒ”–‹ ‹’ƒ–•ǡ ‡•’‡ ‹ƒŽŽ›‹ƒ‰”‘—’™‹–ŠŠ‹‰Š•‡ŽˆǦ”‡’‘”–‡†Ž‡˜‡Ž•‘ˆ„‡Šƒ˜‹‘”ƒŽ‹Š‹„‹–‹‘ǡ•—‰‰‡•–‹‰ –Šƒ– ‘”–‹•‘Ž ƒ‘†—Žƒ–‡„”ƒ‹ƒ –‹˜‹–›ǡ‹ ”‡ƒ•‹‰ƒ’ƒ––‡”–Šƒ–Šƒ•„‡‡ƒ••‘ ‹ƒ–‡† ™‹–Š ƒš‹‡–› ƒ† „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘Ǥ Š‡•‡ ”‡•—Ž–• ”‡’Ž‹ ƒ–‡ ƒ† ‡š–‡† ’”‡˜‹‘—• ˆ‹†‹‰• ‘ˆ  Š—––‡” ƒ† ƒ ‘ ȋʹͲͲͷȌ •Š‘™‹‰ ƒ ‹ ”‡ƒ•‡† ‘””‡Žƒ–‹‘ „‡–™‡‡. ͳͶͳ.

(51) Chapter7. ‹†ˆ”‘–ƒŽ †‡Ž–ƒ ƒ† „‡–ƒ ’‘™‡” ‹ ’ƒ”–‹ ‹’ƒ–• ™‹–Š Š‹‰Š ‘’ƒ”‡† –‘ Ž‘™ „ƒ•ƒŽ ‘”–‹•‘ŽŽ‡˜‡Ž•ǤŠ‡’”‡•‡–•–—†›‹•–Š‡ˆ‹”•––‘•Š‘™–Šƒ–ƒ™‹–Š‹Ǧ•—„Œ‡ –‡š’‡”‹‡–ƒŽ ƒ‹’—Žƒ–‹‘‘ˆ ‘”–‹•‘Ž ƒ‹ ”‡ƒ•‡–Š‹• ‘””‡Žƒ–‹‘ǤŠ‡•‡”‡•—Ž–•ƒ‡‹–—Ž‹‡Ž›–Šƒ– –Š‡•‡†‹ˆˆ‡”‡ ‡• ƒ„‡ƒ––”‹„—–‡†–‘‘–Š‡”ˆƒ –‘”•–Šƒ ‘”–‹•‘ŽǤ

(52) –‡”‡•–‹‰Ž›ǡ ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ‘Ž› ‹ ”‡ƒ•‡† –Š‡ correlation „‡–™‡‡ ‹†ˆ”‘–ƒŽ †‡Ž–ƒ ƒ† „‡–ƒ ’‘™‡”ǡ ƒ† †‹† ‘– Šƒ‰‡ ‡ƒ ȋ‹Ǥ‡Ǥǡ ‰”‘—’Ȍ †‡Ž–ƒ ‘” „‡–ƒ ’‘™‡”ǤŠ‹•‹’Ž‹ ƒ–‡•–Šƒ––Š‡‹ ”‡ƒ•‡† ‘””‡Žƒ–‹‘ ƒ‘–„‡ƒ––”‹„—–‡†–‘ƒ‰‡‡”ƒŽ ‹ ”‡ƒ•‡‘”†‡ ”‡ƒ•‡‘ˆƒ –‹˜‹–›‹–Š‡‡—”ƒŽ•›•–‡•—†‡”Ž›‹‰–Š‡•‡‘• ‹ŽŽƒ–‹‘•ȋˆ‘” ‡šƒ’Ž‡ †—‡ –‘ Šƒ‰‡• ‹ ƒ”‘—•ƒŽȌǡ ƒ† •—‰‰‡•–• –Šƒ– ‘Ž› –Š‡ ‘Š‡”‡ ‡ „‡–™‡‡ ƒ –‹˜‹–›‹–Š‡—†‡”Ž›‹‰•›•–‡•‹•ƒˆˆ‡ –‡†Ǥ . Š‡ ’”‡•‡– ˆ‹†‹‰• ƒ”‡ ‹’‘”–ƒ– ‘•‹†‡”‹‰ –Š‡ ‹ ”‡ƒ•‹‰ ‹–‡”‡•– ‹ –Š‡. ‡ˆˆ‡ –• ‘ˆ ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ‘ Š—ƒ ‡‘–‹‘ ’”‘ ‡••‹‰ ƒ† „‡Šƒ˜‹‘” ȋ‡Ǥ‰Ǥǡ ‡ —‡”˜ƒ‹ǡ‘‘œ‡†ƒƒŽǡ‹–• Šǡ ƒ—‰ŠǡƬ ‘ ǡʹͲͲͲǢ—–ƒ‡–ƒŽǤǡʹͲͲ͹ƒǢ‘”ƒ˜‹ƒ‡– ƒŽǤǡʹͲͲ͸Ǣ‘’•‡–ƒŽǤǡʹͲͲ͵ǡʹͲͲͶǢƒ‡‡”‡–ƒŽǤǡʹͲͲ͹ȌǤ‡•’‹–‡–Š‹•‹–‡”‡•–ƒ†–Š‘—‰Š ’”‡•‡–„”ƒ‹•–ƒ–‡•ƒ›‹ˆŽ—‡ ‡•—„•‡“—‡–’”‘ ‡••‹‰ȋ‡Ǥ‰Ǥǡƒçƒ”ǡʹͲͲ͸Ȍǡ•‘ˆƒ”Ž‹––Ž‡ ™ƒ•‘™ƒ„‘—––Š‡‡ˆˆ‡ –‘ˆ ‘”–‹•‘Ž‘„”ƒ‹ƒ –‹˜ƒ–‹‘ƒ••‘ ‹ƒ–‡†™‹–Š‘–‹˜ƒ–‹‘ƒŽ •–ƒ–‡•Ǥ Ž–Š‘—‰Š •–—†‹‡• ‹˜‡•–‹‰ƒ–‹‰   ˆ”‘–ƒŽ ƒ•›‡–”› ȋƒ ™‹†‡Ž› •–—†‹‡† ‹†‡š ƒ••‘ ‹ƒ–‡† ™‹–Š –Š‡ „ƒŽƒ ‡ „‡–™‡‡ ƒ’’”‘ƒ Š ƒ† ƒ˜‘‹†ƒ ‡ ‘–‹˜ƒ–‹‘ǡ •‡‡ ‡Ǥ‰Ǥǡ ƒ˜‹†•‘ǡ ͳͻͻʹȌ Šƒ˜‡ •Š‘™ ƒ •‹‰‹ˆ‹ ƒ– ”‡Žƒ–‹‘•Š‹’ „‡–™‡‡ Š‹‰Š ‡†‘‰‡‘—• ‘”–‹•‘ŽŽ‡˜‡Ž•ƒ†‡š–”‡‡”‹‰Š–ˆ”‘–ƒŽƒ•›‡–”›‹’”‹ƒ–‡•ȋƒŽ‹‡–ƒŽǤǡͳͻͻͺƒȌƒ† ‹ˆƒ–• ȋ—•• ‡– ƒŽǤǡ ʹͲͲ͵Ȍǡ –Š‹• ”‡Žƒ–‹‘•Š‹’ Šƒ• ‘– „‡‡ ”‡’‘”–‡† ˆ‘” Š‡ƒŽ–Š› Š—ƒ ƒ†—Ž–•ǡ ƒ† •–—†‹‡• ‘ –Š‡ ‡ˆˆ‡ –• ‘ˆ ƒ —–‡ ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ ‹ ƒ†—Ž–• Šƒ˜‡ ’”‘†— ‡† ‹š‡† ”‡•—Ž–• ȋ‘’• ‡– ƒŽǤǡ ʹͲͲͷǡ ʹͲͲ͸ȌǤ ‹˜‡ –Š‡ ‘™ ‰”‘™‹‰ ‡˜‹†‡ ‡ •Š‘™‹‰ƒ ‘•‹•–‡–”‡Žƒ–‹‘•Š‹’‹Š‡ƒŽ–Š›Š—ƒƒ†—Ž–•„‡–™‡‡–Š‡•–”‡‰–Š‘ˆ–Š‡ ‹†ˆ”‘–ƒŽ†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ƒ††‹ˆˆ‡”‡–‡—”‘‡†‘ ”‹‡’ƒ––‡”•ƒ••‘ ‹ƒ–‡†™‹–Š ‘–‹˜ƒ–‹‘ƒŽ•–ƒ–‡•ȋ Š—––‡”Ƭƒ ‘ǡʹͲͲͶǡʹͲͲͷǢ’”‡•‡–•–—†›Ȍ–Š‹•‡ƒ•—”‡ ƒ „‡ ‘•‹†‡”‡†ƒ’”‘‹•‹‰ƒŽ–‡”ƒ–‹˜‡‘”ƒ††‹–‹‘–‘–Š‡ˆ”‘–ƒŽƒ•›‡–”›‡ƒ•—”‡Ǥ ‡ ƒŽ•‘ ˆ‘—† •‹‰‹ˆ‹ ƒ– †‹ˆˆ‡”‡ ‡• ‹ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ „‡–™‡‡ ’ƒ”–‹ ‹’ƒ–• ™‹–Š Ž‘™ ƒ† Š‹‰Š • ‘”‡• ‘ –Š‡ ‡Šƒ˜‹‘”ƒŽ

(53) Š‹„‹–‹‘  ƒŽ‡ ȋƒ”˜‡” Ƭ Š‹–‡ǡ ͳͻͻͶȌǡ ‡•’‡ ‹ƒŽŽ› ƒ– œ ƒˆ–‡” ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘Ǥ Š‡ ˆƒ – –Šƒ– –Š‡ ‰”‘—’ †‹ˆˆ‡”‡ ‡ ™ƒ• ‘•– ’”‘‘— ‡† ƒˆ–‡” ‡š’‡”‹‡–ƒŽ ƒ‹’—Žƒ–‹‘ ‘ˆ ‘”–‹•‘Ž Ž‡˜‡Ž• ‹• ‘•‹•–‡– ™‹–Š ˆ‹†‹‰• ‘ˆ ›ƒœ‡˜ ‡– ƒŽǤ ȋʹͲͲ͸Ȍǡ ™Š‘ ”‡’‘”–‡† ƒ •‹‰‹ˆ‹ ƒ–Ž› Š‹‰Š‡” †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ‹ Š‹‰Š –”ƒ‹– ƒš‹‘—• ’ƒ”–‹ ‹’ƒ–• ‘’ƒ”‡† –‘ Ž‘™ –”ƒ‹– ƒš‹‘—•. ͳͶʹ.

(54) Cortisolenhancesdeltabetacorrelation. ’ƒ”–‹ ‹’ƒ–•ƒˆ–‡”ƒ‡š’‡”‹‡–ƒŽŽ›ƒ‹’—Žƒ–‡†‹ ”‡ƒ•‡‹— ‡”–ƒ‹–›ǤŠ‡•‡ˆ‹†‹‰• •—‰‰‡•– –Šƒ– –Š‡•‡ ‰”‘—’ †‹ˆˆ‡”‡ ‡• „‡ ‘‡ ‘”‡ ’”‘‘— ‡† ƒˆ–‡” ‡š’‡”‹‡–ƒŽ ‹ ”‡ƒ•‡‘ˆƒš‹‘—•‘–‹˜ƒ–‹‘ƒŽ•–ƒ–‡•Ǥ

(55) –Š‡’”‡•‡–•–—†›ǡ–Š‡†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘™ƒ•Š‹‰Š‡•–‹–Š‡Š‹‰Š

(56) ‰”‘—’ ƒˆ–‡” ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘Ǥ

(57) –‡”‡•–‹‰Ž›ǡ‹ƒ•—„•‡“—‡–Ž›ƒ†‹‹•–‡”‡†”‡ƒ –‹‘–‹‡ –ƒ•‡ƒ•—”‹‰ƒ’’”‘ƒ Šƒ†ƒ˜‘‹†ƒ ‡–‡†‡ ‹‡•–‘Šƒ’’›ƒ†ƒ‰”›ˆƒ ‡•ǡ™‡ˆ‘—† ”‡Žƒ–‹˜‡Ž› ˆƒ ‹Ž‹–ƒ–‡† ƒ˜‘‹†ƒ ‡ ”‡ƒ –‹‘• –‘ ƒ‰”› ˆƒ ‡• ‘Ž› ‹ –Š‡•‡ •ƒ‡ Š‹‰Š 

(58)  ’ƒ”–‹ ‹’ƒ–• ƒˆ–‡” ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ǡ ƒ• ‡˜‹†‡ ‡† „› ”‡Žƒ–‹˜‡Ž› ˆƒ•–‡” ”‡ƒ –‹‘ –‹‡• ƒ† ‹ ”‡ƒ•‡† ’‘•‹–‹˜‡ ‡˜‡–Ǧ”‡Žƒ–‡† ’‘–‡–‹ƒŽ• ™Š‡ ’ƒ”–‹ ‹’ƒ–• ƒ˜‘‹†‡† ƒ ƒ‰”› ˆƒ ‡ ȋƒ ‡‡” ‡– ƒŽǤǡ ʹͲͲ͹ȌǤ Š‹• •—‰‰‡•–• –Šƒ– Š‹‰Š †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘• ƒ”‡ ƒ••‘ ‹ƒ–‡†™‹–Šƒ”‡ƒ –‹‘’ƒ––‡””‡Žƒ–‡†–‘•‘ ‹ƒŽƒš‹‡–›ȋ‡Ǥ‰Ǥǡډ‡Ž•Ƭƒ•‡ŽŽǡʹͲͲͶȌǡ –Š‘—‰Š–Š‹•‡‡†•†‹”‡ – ‘ˆ‹”ƒ–‹‘Ǥ ŽŽ ”‡’‘”–‡† ˆ‹†‹‰• ™‡”‡ ‘•– ’”‘‘— ‡† ‘ –Š‡ ‹†ˆ”‘–ƒŽ ƒ† ‡–”ƒŽ ‡Ž‡ –”‘†‡ •‹–‡•ǡ ‘ˆ‹”‹‰ ’”‡˜‹‘—• ˆ‹†‹‰• ‘ˆ  Š—––‡” ƒ† ƒ ‘ ȋʹͲͲͶǡ ʹͲͲͷȌ •—‰‰‡•–‹‰ –Šƒ– –Š‡ ‹†ˆ”‘–ƒŽ ‡Ž‡ –”‘†‡ •‹–‡ ‹• ‘•– •‡•‹–‹˜‡ –‘ ‡—”‘‡†‘ ”‹‡ ƒ‹’—Žƒ–‹‘ƒ†‹†‹˜‹†—ƒŽ†‹ˆˆ‡”‡ ‡•‹†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ǤŠ‡•‡Ž‘ ƒ–‹‘•ƒ”‡‹ Ž‹‡ ™‹–Š •–—†‹‡• ‹˜‡•–‹‰ƒ–‹‰ Ǧ  ”ƒ–‹‘ ‹ ƒ––‡–‹‘ †‡ˆ‹ ‹– Š›’‡”ƒ –‹˜‹–› †‹•‘”†‡” ƒŽ•‘ ”‡’‘”–‹‰ ‘•– ’”‘‘— ‡† †‹ˆˆ‡”‡ ‡• ƒ– ‹†Ž‹‡ ˆ”‘–ƒŽ ƒ† ‡–”ƒŽ ‡Ž‡ –”‘†‡ •‹–‡•ȋ œƒ†œǣ•‡‡—„ƒ”ǡ™ƒ”–™‘‘†ǡ™ƒ”–™‘‘†ǡƬ‹‡”ƒǡͳͻͻͷȌǤ ‹ƒŽŽ›ǡ‹–•Š‘—Ž†„‡‘–‡†–Šƒ–ƒŽ–Š‘—‰Š†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘•™‡”‡•–”‘‰ƒ† •‹‰‹ˆ‹ ƒ– ‘Ž› ‹ –Š‡ Š‹‰Š ƒ† ‘– –Š‡ Ž‘™ 

(59)  ‰”‘—’ǡ ‡•’‡ ‹ƒŽŽ› ƒˆ–‡” ‘”–‹•‘Ž ƒ†‹‹•–”ƒ–‹‘ǡ –Š‡•‡ †‹ˆˆ‡”‡ ‡• ‘Ž› ƒ’’”‘ƒ Š‡† •–ƒ–‹•–‹ ƒŽ •‹‰‹ˆ‹ ƒ ‡ ƒ– ‹†ˆ”‘–ƒŽ ƒ† ‡–”ƒŽ ‡Ž‡ –”‘†‡•Ǥ Š‹• ƒ› „‡ †—‡ –‘ ƒ Žƒ  ‘ˆ ’‘™‡” ‹ ‘—” •–—†›Ǥ Š—•ǡ •–—†‹‡• ‹ Ž—†‹‰Žƒ”‰‡”’ƒ”–‹ ‹’ƒ–••ƒ’Ž‡•ƒ”‡‡‡†‡†–‘”‡’Ž‹ ƒ–‡‘—”ˆ‹†‹‰•Ǥ ƒ•‡† ‘ –Š‡‘”‹‡• ƒ••‘ ‹ƒ–‹‰  ™‹–Š ȋ•—„ ‘”–‹ ƒŽŽ› †”‹˜‡Ȍ ‘–‹˜ƒ–‹‘ƒŽ ‘” ‡‘–‹‘ƒŽ’”‘ ‡••‡•ƒ† ™‹–Š ‘”–‹ ƒŽŽ›†”‹˜‡ ‘‰‹–‹˜‡’”‘ ‡••‡•ǡ•‡˜‡”ƒŽƒ—–Š‘”• Šƒ˜‡ •—‰‰‡•–‡† –Šƒ– ‡Šƒ ‡† Ǧ  ‘””‡Žƒ–‹‘• ”‡ˆŽ‡ – ‹ ”‡ƒ•‡† ‘—‹ ƒ–‹‘ „‡–™‡‡ •—„ ‘”–‹ ƒŽ ƒ† ‘”–‹ ƒŽ „”ƒ‹ ”‡‰‹‘•ǡ ‘” ‡˜‡ ‹ ”‡ƒ•‡† ‘”–‹ ƒŽ ‘–”‘Ž ‘˜‡” •—„ ‘”–‹ ƒŽ†”‹˜‡•ȋ›ƒœ‡˜ƬŽ‘„‘†•ƒ›ƒǡʹͲͲ͵Ǣ‘„‹•‘ʹͲͲͳǢ Š—––‡”Ƭƒ ‘ǡ ʹͲͲͷȌǤ Ž–Š‘—‰Š •— Š ‹–‡”’”‡–ƒ–‹‘ ‘ˆ –Š‡ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ƒ• ƒ ‹†‡š ‘ˆ –Š‡ ‹ˆ‘”ƒ–‹‘‡š Šƒ‰‡„‡–™‡‡•—„ ‘”–‹ ƒŽƒ† ‘”–‹ ƒŽ„”ƒ‹•›•–‡•‹••–‹ŽŽ•’‡ —Žƒ–‹˜‡ǡ ‹– ˆ‹–• ™‹–Š –Š‡ ˆ‹†‹‰• ‘ˆ —‡”‘—• †‹”‡ – ƒ† ‹†‹”‡ – ‘‡ –‹‘• „‡–™‡‡ ‘”–‹ ƒŽ ƒ† •—„ ‘”–‹ ƒŽ •›•–‡• ȋ‡Ǥ‰Ǥǡ ƒ”„ƒ•ǡ ʹͲͲͲȌǡ ƒ† ‹• ‹ ƒ‰”‡‡‡– ™‹–Š –Š‡ ‘–‹‘ –Šƒ–. ͳͶ͵.

(60) Chapter7. –Š‡•‡ ‘‡ –‹‘•’Žƒ›ƒ‹’‘”–ƒ–”‘Ž‡‹–Š‡”‡‰—Žƒ–‹‘‘ˆ‡‘–‹‘ƒ†„‡Šƒ˜‹‘”ȋ‡Ǥ‰Ǥǡ ‡‘—šǡʹͲͲͲǢ Š•‡”Ƭ ”‘••ǡʹͲͲͷǢŠ‡Ž’•ǡʹͲͲ͸ȌǤ ‡ ‡ǡ–Š‹•‹–‡”’”‡–ƒ–‹‘ƒ›„‡ —•‡†ƒ•ƒŠ‡—”‹•–‹ ‘†‡ŽǡƒŽ–Š‘—‰Š ˆ—–—”‡•–—†‹‡•ƒ”‡‡‡†‡†–‘ˆ—”–Š‡”‹˜‡•–‹‰ƒ–‡–Š‡ˆ— –‹‘ƒŽ•‹‰‹ˆ‹ ƒ ‡‘ˆ–Š‡†‡Ž–ƒǦ „‡–ƒ ‘””‡Žƒ–‹‘Ǥ ‘” ‡šƒ’Ž‡ǡ –Š‡ ‹†‡–‹ˆ‹ ƒ–‹‘ ‘ˆ –Š‡ ˆ— –‹‘ƒŽ ‡—”‘ƒƒ–‘‹ ƒŽ ‘””‡Žƒ–‡•‘ˆ‹ ”‡ƒ•‡•‘”†‡ ”‡ƒ•‡•‹†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ȋ—•‹‰ˆ— –‹‘ƒŽƒ‰‡–‹  ‡•‘ƒ ‡

(61) ƒ‰‹‰‘””ƒ• ”ƒ‹ƒŽƒ‰‡–‹ –‹—Žƒ–‹‘Ȍƒ›Š‡Ž’–‘†‡ˆ‹‡–Š‡„”ƒ‹ •›•–‡•–Šƒ–”‡Žƒ–‡–‘•Š‹ˆ–•‹ƒš‹‘—•Ȁ‹Š‹„‹–‡†‘”‹’—Ž•‹˜‡‘–‹˜ƒ–‹‘ƒŽ•–ƒ–‡•ǡƒ† ›‹‡Ž†‘”‡‹•‹‰Š–‹–‘™Šƒ–‡š–‡––Š‹• ‘””‡Žƒ–‹‘‹•”‡Žƒ–‡†–‘‹Š‹„‹–‘”›‘”‡š ‹–ƒ–‘”› ‘‡ –‹‘•Ǥ

(62) ƒ††‹–‹‘ǡ•–—†‹‡•™‹–Š™‹–Š‹Ǧ•—„Œ‡ –‡ƒ•—”‡•‘ˆ†‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ”‡Žƒ–‡† –‘ –ƒ• ’‡”ˆ‘”ƒ ‡ ƒ› ’”‘˜‹†‡ ‘”‡ ‹•‹‰Š– ‹–‘ –Š‡ ”‡Žƒ–‹‘ „‡–™‡‡ –Š‹• ‘–‹˜ƒ–‹‘ƒŽ•–ƒ–‡ƒ†•—„•‡“—‡–‡‘–‹‘’”‘ ‡••‹‰ƒ†„‡Šƒ˜‹‘”Ǥ

(63) •—ǡ–Š‡’”‡•‡–•–—†›•Š‘™•–Šƒ– ‘”–‹•‘Žƒ†‹‹•–”ƒ–‹‘–‡†‡†–‘‹ ”‡ƒ•‡ –Š‡ ‘””‡Žƒ–‹‘ „‡–™‡‡  ȋ†‡Ž–ƒȌ ƒ†  ȋ„‡–ƒȌ ƒ –‹˜‹–› ‘’ƒ”‡† –‘ ’Žƒ ‡„‘Ǥ

(64)  ƒ††‹–‹‘ǡ †‡Ž–ƒǦ„‡–ƒ ‘””‡Žƒ–‹‘ ™ƒ• Š‹‰Š‡” ‹ Š‹‰Š ‘’ƒ”‡† –‘ Ž‘™ „‡Šƒ˜‹‘”ƒŽŽ› ‹Š‹„‹–‡† •—„Œ‡ –•ǡ ƒ† –Š‹• ‰”‘—’ †‹ˆˆ‡”‡ ‡ ™ƒ• ‘•– ’”‘‘— ‡† ƒˆ–‡” ‘”–‹•Ž ƒ†‹‹•–”ƒ–‹‘ǤŠ‡•‡”‡•—Ž–••—‰‰‡•––Šƒ– ‘”–‹•‘Ž ƒ‘†‹ˆ›„”ƒ‹ƒ –‹˜‹–›ǡ‹ ”‡ƒ•‹‰ƒ ’ƒ––‡” ƒ••‘ ‹ƒ–‡† ™‹–Š ƒš‹‡–› ƒ† „‡Šƒ˜‹‘”ƒŽ ‹Š‹„‹–‹‘Ǥ Š‹• ˆ‹†‹‰ ‹• ’ƒ”–‹ —Žƒ”Ž› ‹–‡”‡•–‹‰‹–Š‡Ž‹‰Š–‘ˆ‘–‹‘•–Šƒ– ‘”–‹•‘Ž’”‡’ƒ”‡•–Š‡‘”‰ƒ‹•ˆ‘”ƒ†ƒ’–‹˜‡•–”‡•• ”‡ƒ –‹‘• ƒ† ˆƒ ‹Ž‹–ƒ–‡• ‘‰‹–‹˜‡ ’”‘ ‡••‡• ‘” „‡Šƒ˜‹‘” –Šƒ– ‹• ‘•– ”‡Ž‡˜ƒ– –‘ –Š‡ •‹–—ƒ–‹‘ȋ‡Ǥ‰Ǥǡ‡Ž‘‡–‡–ƒŽǤǡͳͻͻͻǢ‘’•‡–ƒŽǤǡʹͲͲ͸ȌǤ. ͳͶͶ.

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