University of Groningen
Early detection of left ventricular remodeling
Hendriks, Tom
DOI:
10.33612/diss.144600179
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Publication date: 2020
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Hendriks, T. (2020). Early detection of left ventricular remodeling. University of Groningen. https://doi.org/10.33612/diss.144600179
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EARLY DETECTION OF
LEFT VENTRICULAR
REMODELING
COLOFON
The research described in this thesis was performed at the Department of Cardiology of the University Medical Center Groningen, the Netherlands.
Financial support by the following sponsors for the publication of this thesis is gratefully acknowledged:
Rijksuniversiteit Groningen, Groningen University Institute for Drug Exploration (GUIDE). SBOH, employer of GP trainees.
Copyright © 2020 by Tom Hendriks. All rights reserved. Any unauthorized reprint or use of this material is prohibited. No part of this thesis may be reproduced, stored or transmitted in any form or by any means, without written permission of the author or, when appropriate, of the publishers of the publications.
Early detection of
left ventricular remodeling
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen op gezag van de rector magnificus prof. dr. C. Wijmenga
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op 11 november 2020 om 18 uur
door
Tom Hendriks
geboren op 8 januari 1989
te Utrecht
Promotores
Prof. dr. P. van der Harst Prof. dr. D.J. van Veldhuisen
Copromotor
Dr. E. Lipsic
Beoordelingscommissie
Prof. dr. P. van der Meer Prof. dr. R.T. Gansevoort Prof. dr. R. Nijveldt
Financial support by the Dutch Heart Foundation for the publication of this thesis is gracefully acknowledged.
Paranimfen
Marije Hendriks Lawien Al Ali
TABLE OF CONTENTS
Chapter 1. Introduction 9
PART I: CARDIOVASCULAR RISK FACTORS
Chapter 2. Active tobacco smoking impairs cardiac systolic function 21
Chapter 3. Effect of systolic blood pressure on left ventricular structure and 37
function: a Mendelian randomization study
PART II: MYOCARDIAL INFARCTION
Chapter 4. Predictors of left ventricular remodeling after ST-elevation 67
myocardial infarction
Chapter 5. Agreement of 2D transthoracic echocardiography with cardiovascular 85
magnetic resonance imaging after ST-elevation myocardial infarction
Chapter 6. Left ventricular restoration devices post myocardial infarction 103
PART III: IMPROVEMENTS
Chapter 7. Improving indexation of left ventricular volumes using lean body 129
mass and RR-interval
Chapter 8. A primer in Artificial Intelligence (AI) in cardiovascular medicine 149
Chapter 9. General discussion and future perspectives 167
Appendices Nederlandse samenvatting 184
Acknowledgements 186 Curriculum vitae 188 List of publications 190
