Kuijl, C.P.
Citation
Kuijl, C. P. (2008, October 15). Regulation of endosomal and phagosomal transport.
Retrieved from https://hdl.handle.net/1887/13146
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Regulation of Endosomal and Phagosomal Transport
Coenraad Paul Kuijl
Regulation of Endosomal and Phagosomal Transport Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van Rector Magnificus prof.mr. P.F. van der Heijden, volgens besluit van het College voor Promoties
te verdedigen op woensdag 15 oktober 2008 klokke 13.45 uur
door
Coenraad Paul Kuijl geboren te Alkmaar
in 1976
Promotor Prof. Dr. J.J. Neefjes Referent Prof. Dr. W.H. Moolenaar Overige leden Prof. Dr. F. Koning
Prof. Dr. T.H.M. Ottenhoff Prof. Dr. H. Overkleeft
Prof. Dr. J. Borst (Universiteit van Amsterdam) Prof. Dr. P.J. Peters (Nederlands Kanker Instituut, Vrije Universiteit Amsterdam)
© 2008 C.P. Kuijl
Cover: ‘chemistry to elucidate complex networks’
The research described in this thesis was performed at the Division of Tumor Biology of the Netherlands Cancer Institute (NKI/AvL) and supported by The Netherlands Organization for Scientific Research (NWO) and the Dutch Can- cer Society (KWF).
Financial support for the publication of this thesis was provided by: The Neth- erlands Cancer Institute (NKI/AvL), The Dutch Cancer Society (KWF) and the Dutch Society for Microscopy (NVvM).
Contents
Introduction 7
Chapter 1 Rab Proteins, Connecting Transport and Vesicle Fusion
Traffic, Volume 6 Issue 12, December 2005
13
Chapter 2 Dynein-mediated Vesicle Transport Controls Intracellular Salmonella Replication
Molecular Biology of the Cell, Volume15, Issue 6, June 2004
23
Chapter 3 Spatial Separation of HLA-DM/HLA-DR Interactions within MIIC and Phagosome-Induced Immune Escape
Immunity, Volume 22, Issue 2, February 2005
37
Chapter 4 The Molecular Mechanism of Cholesterol Control of Late Endosomal Transport by Dynein Motors
Cell, submitted
61
Chapter 5 Reciprocal Chemical Genetics for swift lead and target identification
Molecular BioSystems, Volume 4, Issue 10, September 2008
93
Chapter 6 Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1
Nature, Volume 450, 29 November 2007
103
Summary and discussion 133
Nederlandse samenvatting 137
List of publications 141
Curiculum vitae 143
