• No results found

Doublecortin-like kinase and neuronal differentiation Dijkmans, T.F.

N/A
N/A
Protected

Academic year: 2021

Share "Doublecortin-like kinase and neuronal differentiation Dijkmans, T.F."

Copied!
7
0
0

Bezig met laden.... (Bekijk nu de volledige tekst)

Hele tekst

(1)

Citation

Dijkmans, T. F. (2009, October 14). Doublecortin-like kinase and neuronal differentiation. Retrieved from https://hdl.handle.net/1887/14055

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/14055

Note: To cite this publication please use the final published version (if applicable).

(2)

Chapter8

LISTOFABBREVIATIONS

CURRICULUMVITAE

PUBLICATIONS















































OUTLINE

1.Listofabbreviations

2.Curriculumvitae

3.Publications

(3)

1.LISTOFABBREVIATIONS



Atf1/2/3 ActivatingTranscriptionFactor1/2/3

CARP  CaMKRelatedPeptide(aliasAnia4)

CDK5  CyclinDependentkinase5

cFos  vFosFBJmurineosteosarcomaviraloncogenehomolog

Cited2  Cbp/p300Interactingtransactivator2

CRE  cAMPResponseElement

CREB  CREBindingprotein

DCAMKL1 synonymofDCLK

DCL  DoubleCortinLike(splicevariantofDCLK)

DCLK  DoubleCortinLikeKinase(aliasDCAMKL1)

DCX  DoubleCortin(XChromosomal)

DEX  DEXxamethasone

DRG  DelayedResponseGene

EGF  EpidermalGrowthFactor

Egr1  EarlyGrowthResponse1

ERK1/2  ExtracellularsignalRegulatedKinase1/2

FC  FoldChange

FSK  ForSKolin

GAP43  GrowthAssociatedProtein43

GR  GlucocorticoidReceptor

Grb2  GrowthReceptorBound2

GRE  GlucocorticoidResponseElement

IEG  ImmediateEarlyGene

JNK  JunNterminalKinase

Klf10/Tieg KruppelLikeFactor10

Klf4  KruppelLikeFactor4

Maff vMAFmusculoaponeuroticfibrosarcomaoncogenefamily,

proteinF

MAP  MicrotubuleAssociatedProtein

MAPK  MitogenActivatedProteinKinase

MARK  MAP/microtubuleaffinityRegulatingKinase1

MR  MineralocorticoidReceptor

NGF  NerveGrowthFactor

Ns1PC12 Neuroscreen1Pheochromocytoma12

PI3K  PhosphatidylInositol3Kinase

PKA  ProteinKinaseA

PKC  ProteinKinaseC

PLC  PhosphoLipaseCgamma

PP1/2  ProteinPhosphatase1/2

qPCR  Quantitative/realtimePCR

RP  RetinitisPigmentosa

(4)

SBH  SubcorticalBandHeteropia

SEM  StandardErroroftheMean

TORC2  TransducerOfRegulatedCREBActivity2

TrkA  TropomyosinRelatedKinaseA

 

(5)

2.CURRICULUMVITAE





ThomasFrederikDijkmanswerdop13maart1979geborenteLeiden.Hijbehaalde

in 1997 zijn VWO diploma aan het  Northgo College te Noordwijk. Vervolgens

begonhijin1997metdestudieBiologieaandeUniversiteitLeiden.Alsonderdeel

van deze opleiding heeft hij een onderzoeksstage gelopen bij de vakgroep

Gistgenetica van de Universiteit Leiden (Dr. Y. Steensma) en bij de vakgroep

OncologyandPathologyvanhetKarolinskaInstituut(Prof.Dr.R.Kiessling).In2003

heeft hij zijn doctoraal behaald en werkte daarna 6 maanden als junior

onderzoeker bij de vakgroep Medische Farmacologie van de Universiteit Leiden

(LACDR/LUMC). Aansluitend is hij in 2004 bij deze vakgroep begonnen aan zijn

promotieonderzoekonderbegeleidingvanDr.E.Vreugdenhil.



(6)

3.PUBLICATIONS





1. Dijkmans TF, Van Hooijdonk LW, Fitzsimons CP, Vreugdenhil E. The

doublecortin gene family and disorders of neuronal structure. (Review).

CentNervSystAgentsMedChem.Inpress.

2. VanHooijdonkLW,IchwanM,DijkmansTF,SchoutenTG,DeBackerMW,

Adan RA, Verbeek FJ, Vreugdenhil E and Fitzsimons CP. Lentivirus

mediatedtransgenedeliverytothehippocampusrevealssubfieldspecific

differencesinexpression.BMCNeurosci.2009Jan13;10:2.

3. DijkmansTF,vanHooijdonkLW,SchoutenTG,KamphorstJT,Fitzsimons

CP, Vreugdenhil E. Identification of new Nerve Growth Factorresponsive

immediateearlygenes.BrainRes.2009Jan16;1249:1933.

4. Van der Laan S, Sarabdjitsingh RA, Van Batenburg MF, Lachize SB, Li H,

Dijkmans TF, Vreugdenhil E, de Kloet ER, Meijer OC. Chromatin

immunoprecipitation scanning identifies glucocorticoid receptor binding

regions in the proximal promoter of a ubiquitously expressed

glucocorticoid target gene in brain. J Neurochem. 2008 Sep;106(6):2515

23.

5. DijkmansTF,vanHooijdonkLW,SchoutenTG,KamphorstJT,VellingaAC,

Meerman JH, Fitzsimons CP, de Kloet ER, Vreugdenhil E. Temporal and

functional dynamics of the transcriptome during nerve growth factor

induceddifferentiation.JNeurochem.2008Apr9.

6. Fitzsimons CP, Ahmed S, Wittevrongel CF, Schouten TG,Dijkmans TF,

Scheenen WJ, Schaaf MJ, de Kloet ER, Vreugdenhil E. The microtubule

associated protein doublecortinlike regulates the transport of the

glucocorticoidreceptorinneuronalprogenitorcells.MolEndocrinol.2008

Feb;22(2):24862

7. Meijer OC, Kalkhoven E, van der Laan S, Steenbergen PJ, Houtman SH,

DijkmansTF,PearceD,deKloetER.Steroidreceptorcoactivator1splice

variants differentially affect corticosteroid receptor signaling.

Endocrinology.2005Mar;146(3):143848.

(7)

Referenties

GERELATEERDE DOCUMENTEN

In addition, two transgenic mouse lines were generated with over- expression of CARP and a line with over-expression of a constitutively active form of DCLK-short in the brain

The studies described in the thesis have been performed at the Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research (LACDR) and Leiden University Medical

A second type of transcript that is, like the DCLK-long variants, derived from the first transcription start site of the DCLK gene, contains the highly conserved DCX domains, but

a correlation between CARP mRNA expression and ADX-induced apoptosis in DG granule cells and specific expression of CARP in these apoptotic neurons.. Moreover,

x In Ns1 PC12 cells, NGF induces DCLKshort expression and activates ERK.. 1/2mediated phosphorylation. NGFinduced neuritogenesis

In Chapter 5, the regulation of DCLKshort expression in Ns1 PC12 cells

cal microscopy. Control treatment retained the n D produced actin aggregates after disruption row heads, DCLK-short and F-actin colocalize wth cones in control treatments, whereas

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden. Downloaded