Sec translocase in action
Komarudin, Amalina Ghaisani
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Publication date:
2019
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Komarudin, A. G. (2019). Sec translocase in action: Translocation initiation and processivity. University of
Groningen.
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Sec translocase in action
Translocation initiation and processivity
ISBN: 978-94-034-1773-8 (Printed version) ISBN: 978-94-034-1772-1 (Electronic version)
The research presented in this thesis was performed in the research group of Molecular Microbiology of the Groningen Biomolecular Science and Biotechnology, University of Groningen, UIF/FUIFSMBOETBOEXBTmOBODJBMMZTVQQPSUFECZUIFJODFOUJWFTDIFNFPGUIF;FSOJLF*OTUJUVUFGPS Advanced Materials and by the Foundation of Life Sciences of the Netherlands Organization for 4DJFOUJmD3FTFBSDI "-8/80
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© 2019, Amalina Ghaisani Komarudin
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Sec translocase in action
Translocation initiation and processivity
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the 5HFWRU0DJQL¿FXVSURI(6WHUNHQ
and in accordance with WKHGHFLVLRQE\WKH&ROOHJHRI'HDQV This thesis will be defended in public on
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by
Amalina Ghaisani Komarudin
born on 24 February 1990 in Bandung, Indonesia
TABLE OF CONTENTS
Chapter 1
SecA Mediated Protein Translocation Through SecYEG Channel 10
Chapter 2
Engineering of the Two-helix Finger of SecA ATPase 40
Chapter 3
4FD:&(.FEJBUFT5SBOTMPDBUJPOPG4FDSFUPSZ1SPUFJO.PEJmFEXJUI/PO1PMZQFQUJEF Segments
54
Chapter 4
Dynamics of the Interaction between the Two-helix Finger of SecA ATPase and SecYEG 74 Chapter 5 Summary 94 Samenvatting 101 3JOHLBTBO 107 Appendices "DLOPXMFEHFNFOUT 116
About the Author 121
