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University of Groningen

Tongue coating

Seerangaiyan, Kavitha

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2018

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Seerangaiyan, K. (2018). Tongue coating: It’s impact on intra-oral halitosis and taste. Rijksuniversiteit Groningen.

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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TONGUE COATING

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The research reported in this thesis was carried out at the center for dentistry and oral hygiene, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Layout design: Kavitha Seerangaiyan Cover design: Kavitha Seerangaiyan

Printed by: Ridderprint B.V (https://www.ridderprint.nl/) ISBN: 978-94-034-1074-6 (printed version)

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The research reported in this thesis was carried out at the center for dentistry and oral hygiene, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Layout design: Kavitha Seerangaiyan Cover design: Kavitha Seerangaiyan

Printed by: Ridderprint B.V (https://www.ridderprint.nl/) ISBN: 978-94-034-1074-6 (printed version)

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Tongue coating

It’s impact on intra-oral halitosis and taste

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the Rector Magnificus Prof. dr. E. Sterken

and according to the decision of the Doctorate Board. This thesis will be defended in public on Wednesday 28 November 2018 at 11:00 hours

by

Kavitha Seerangaiyan

born on 7 September 1983 in Oddanchatram, India

Supervisor

Prof. E.G. Winkel

Prof. A.J. van Winkelhoff

Co-supervisor

Dr. P.J.W. Jüch

Assessment Committee

Prof. A. Vissink Prof. C. de Baat Prof. H. van der Mei

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Tongue coating

It’s impact on intra-oral halitosis and taste

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the Rector Magnificus Prof. dr. E. Sterken

and according to the decision of the Doctorate Board. This thesis will be defended in public on Wednesday 28 November 2018 at 11:00 hours

by

Kavitha Seerangaiyan

born on 7 September 1983 in Oddanchatram, India

Supervisor

Prof. E.G. Winkel

Prof. A.J. van Winkelhoff

Co-supervisor

Dr. P.J.W. Jüch

Assessment Committee

Prof. A. Vissink Prof. C. de Baat Prof. H. van der Mei

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You are the creator of your own destiny

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You are the creator of your own destiny

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Contents

Chapter 1

1

General introduction.

13

Chapter 2

Tongue coating: its characteristics and role in intra-oral halitosis and general health: A review.

Chapter 3

33

The tongue microbiome in healthy subjects and patients with intra-oral halitosis.

Chapter 4

53

Untargeted metabolomic analysis of the bacterial tongue coating of intra-oral halitosis patients.

Chapter 5

77

Tongue cleaning increases the perceived intensity of salty taste.

Chapter 6

87

General discussion, conclusion and future prospective

Summary

95

Samenvatting

98

Acknowledgements

101

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Contents

Chapter 1

1

General introduction.

13

Chapter 2

Tongue coating: its characteristics and role in intra-oral halitosis and general health: A review.

Chapter 3

33

The tongue microbiome in healthy subjects and patients with intra-oral halitosis.

Chapter 4

53

Untargeted metabolomic analysis of the bacterial tongue coating of intra-oral halitosis patients.

Chapter 5

77

Tongue cleaning increases the perceived intensity of salty taste.

Chapter 6

87

General discussion, conclusion and future prospective

Summary

95

Samenvatting

98

Acknowledgements

101

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CHAPTER

1

General Introduction

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