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Dentritic cells and the battle against arthritis Duivenvoorde, L.M. van

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Dentritic cells and the battle against arthritis

Duivenvoorde, L.M. van

Citation

Duivenvoorde, L. M. van. (2007, October 10). Dentritic cells and the battle against arthritis. Retrieved from https://hdl.handle.net/1887/12372

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/12372

Note: To cite this publication please use the final published version (if applicable).

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Dendritic cells

and

the battle

against arthritis

Leonie van Duivenvoorde

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Dendritic cells and the battle

against arthritis

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op woensdag 10 oktober 2007

klokke 15.00 uur

door

Leonie Maria van Duivenvoorde geboren te Heemskerk in 1978

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Promotiecommissie:

Promotor: Prof. Dr. T.W.J. Huizinga, MD

Co-Promotor: Dr. R.E.M. Toes

Referent: Prof. Dr. M.Yazdanbakhsh

Overige leden: Prof. Dr. C.J.M. Melief

Prof. Dr. C. Jorgensen, MD INSERM U475 te Montpellier Dr. C. van Kooten

Dr. J. Kuiper Leiden/Amsterdam Center for drug research

te Leiden

Dr. E. Lubberts Erasmus Universeit te Rotterdam

The research presented in this thesis was performed at the Department of Rheumatology of the Leiden University Medical Center, The Netherlands, and was financed by the Dutch Arthritis Association (Reumafonds).

Financial support for the publication of this thesis was provided by the Dutch Arthritis Association and the J.E. Jurriaanse Stichting.

Cover: Sjaak van Duivenvoorde and Tony Toebak Cover photo: Wanda Han

Lay-out: Tony Toebak

Printed by: Optima Grafische Communicatie, Rotterdam ISBN Number: 978-90-8559-148-1

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Contents

Chapter 1 Introduction

Chapter 2 Antigen-specific immunomodulation of collagen-induced arthritis with tumor necrosis factor-stimulated dendritic cells.

Arthritis Rheum. 2004 Oct;50(10):3354-64.

Chapter 3 Immunomodulatory dendritic cells inhibit Th1-responses and arthritis via different mechanisms.

Journal of Immunology 2007 Aug 1; 179(3):1506-1515.

Chapter 4 Immature Dendritic Cells Suppress Collagen-Induced Arthritis By In Vivo Expansion Of CD49b+ Regulatory T Cells.

Journal of Immunology 2006 Sep 15; 177(6):3806-3813.

Chapter 5 Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells.

Arthritis Rheum. 2005 Jul;52(7):2212-21.

Chapter 6 OxLDL-pulsed dendritic cells: an immunotherapy in atherosclerosis

Submitted for publication

Chapter 7 Summary and discussion

Adapted from:”Dendritic Cells, vehicles for tolerance induction and prevention of autoimmune diseases.”

Immunobiology 2006 Sept; 211:627-632. (review)

Chapter 8 Nederlandse samenvatting

Abbreviations

Curriculum Vitae

List of publications

Nawoord

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