Cover Page
The handle
http://hdl.handle.net/1887/138385
holds various files of this Leiden
University dissertation.
Author: Bartels, D.J.P.
Title: Placebo and nocebo effects on itch: An experimental approach
Issue date: 2020-11-18
Placebo and nocebo effects on itch
An experimental approach
Author: Danielle Bartels
Cover design: Harm Langenkamp & Ridderprint Lay-out: Danielle Bartels
Printing: Ridderprint | www.ridderprint.nl
© Copyright Danielle Bartels, 2020
All rights reserved. No part of this thesis may be reproduced or transmitted in any form or by any means without written permission from the author.
The research presented in this thesis was partially carried out at the Health, Medical and Neuropsychology Unit of Leiden University, Leiden and partially at the Department of Medical Psychology of the Radboud University Medical Center, Nijmegen, the Netherlands.
The research was funded by an Innovation Scheme (Vidi) Grant from the Netherlands Organization for Scientific Research (NWO) and a Consolidator Grant from the European Research Council (ERC), both granted to A.W.M. Evers.
Placebo and nocebo effects on itch
An experimental approach
Proefschrift
Ter verkrijging van
De graad van Doctor aan de Universiteit Leiden, Op gezag van Rector Magnificus prof. Mr. C.J.J.M. Stolker,
Volgens besluit van het College voor Promoties Te verdedigen op woensdag 18 november 2020
Klokke 15.00 uur
Door
Danielle Julia Petronella Bartels
Geboren te Nijmegen In 1988
Promotores
Prof. dr. A.W.M. Evers
Prof. dr. P.C.M. van de Kerkhof (Radboud University Medical Center)
Copromotor
Dr. A.I.M. van Laarhoven
Promotiecommissie
Prof. dr. A.J.W. van der Does (secretaris)
Prof. dr. E.M.G.J de Jong (Radboud University Medical Center) Prof. dr. H.C. Dijkerman (Utrecht University)
Contents
Chapter 1 General introduction 7
Chapter 2 Placebo and nocebo effects on itch: effects, mechanisms, and predictors
23
Chapter 3 Role of conditioning and verbal suggestion in placebo and nocebo effects on itch
35
Chapter 4 Minimizing nocebo effects by conditioning with verbal suggestion: a randomized clinical trial in healthy humans
55
Chapter 5 Nocebo effects and scratching behaviour on itch 83 Chapter 6 Cognitive schemas in placebo and nocebo responding: role of
autobiographical memories and expectations
105
Chapter 7 Summary & General discussion 127
Samenvatting (Dutch summary) 151
Curriculum Vitae 155
Publications 157
