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Cover Page

The handle http://hdl.handle.net/1887/92369 holds various files of this Leiden University

dissertation.

Author: Meeuwis, S.H.

Title: Placebo and nocebo effects in itch : from conditioning to psychophysiological

effects

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1

Placebo and nocebo effects in itch

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Author: Stefanie Meeuwis Cover design: Céline Meeuwis

Printing: GVO Drukkers & Vormgevers BV

© Copyright Stefanie Meeuwis, 2020

All rights reserved. No part of this thesis may be reproduced or transmitted in any form or by any means without written permission from the author.

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Placebo and nocebo effects in itch

From conditioning to psychophysiological effects

Proefschrift

Ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,

volgens besluit van het College voor Promoties te verdedigen op woensdag 3 juni 2020

klokke 13.45 uur

door

Stefanie Helena Meeuwis

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Promotor

Prof. dr. A.W.M. Evers

Copromotoren: Dr. H. van Middendorp Dr. D.S. Veldhuijzen Promotiecommissie: Prof. dr. J.F. Brosschot Prof. dr. M.H. Vermeer

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TABLE OF CONTENT

Chapter 1. General introduction 7

Chapter 2. Placebo and nocebo effects across itch and dermatological 23

conditions: a systematic review Chapter 3. Antipruritic placebo effects by conditioning H1-antihistamine 99

Chapter 4. Placebo effects of open-label verbal suggestions on itch 151

Chapter 5. Effects of open- and closed-label nocebo and placebo 171

suggestions on itch and itch expectations Chapter 6. Open- and closed-label placebo and nocebo suggestions 203

about a sham transdermal patch: effects on itch Chapter 7. Summary and General Discussion 243

Nederlandse samenvatting 271

Curriculum Vitae 279

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