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Acute leukaemia in children : aspects of diagnosis and treatment Willemze, A.J.

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Citation

Willemze, A. J. (2009, September 3). Acute leukaemia in children : aspects of diagnosis and treatment. Retrieved from https://hdl.handle.net/1887/13950

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/13950

Note: To cite this publication please use the final published version (if applicable).

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Acute leukaemia in children

Aspects of diagnosis and treatment

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The research described in this thesis was performed in the Laboratory of Immunology, Department of Pediatrics, Leiden University Medical Center (LUMC), Leiden, the Netherlands, and was financially supported by the LUMC and Dutch Cancer Society (KWF) project grant: KWF RUL 2001-2515.

Financial support for the publication of this thesis was provided by the Jurriaanse Stichting, Genzyme, Novartis Pharma B.V., Sanquin and the Dutch Cancer Society.

©Willemze, AJ, 2009

All rights reserved. No parts of this thesis may by reproduced or transmitted, in any form or by any means, without permission of the author.

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Acute leukaemia in children Aspects of diagnosis and treatment

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op donderdag 3 september 2009

klokke 13:45 uur

door

Annemieke Johanna Willemze

geboren te Amsterdam In 1972

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and relapse location in a patient with childhood T-ALL Blood 2004;103(7):2806-2808

Chapter 3

47

The role of CCR2, CCR5, CXCR4 and CXCR7 in extramedullary leukaemia of the skin and on leukaemic blast survival in childhood AML

Submitted to Leukemia

Part II

Aspects of haematopoietic stem cell transplantation

Chapter 4

69

HLA-identical haematopoietic stem cell transplantation for acute leukaemia in children: less relapse with higher biologically effective dose of TBI

Bone Marrow Transplantation 2007;40(4):319-327

Chapter 5

91

Cyclosporine A kinetics in children after stem cell transplantation British Journal of Clinical Pharmacology 2008; 66(4):539-45.

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Chapter 6

109 Cyclosporine A exposure is associated with acute GVHD and relapse in

children after stem cell transplantation Submitted to Bone Marrow Transplantation

Chapter 7

125

The effect of Graft-versus-Host Disease on skin endothelial and epithelial cell chimerism in stem cell transplant recipients Transplantation 2009; 87(7):1096-101

Chapter 8

141

Summary and general discussion

Chapter 9

153

Nederlandse samenvatting

Curriculum Vitae 159

List of publications 161

Figure section 165

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