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Cover Page

The handle http://hdl.handle.net/1887/49516 holds various files of this Leiden University dissertation

Author: Verbeek, Lianne

Title: Neonatal hematological and biochemical complications in TTTS and TAPS

Issue Date: 2017-06-13

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Neonatal hematological and biochemical complications

in TTTS and TAPS

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Neonatal hematological and biochemical complications in TTTS and TAPS

© Lianne Verbeek, 2017, Leiden, The Netherlands

No part of this thesis may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy or any information storage or retrieval system, without permission of the copyright owner.

ISBN: 978-90-9030370-3

Cover design: Lianne Verbeek, Maikel Rolvink Design: Robert Huiberts

Printing: Zalsman Print B.V.

The research presented in this thesis was performed at the Department of Pediatrics, Leiden University Medical Center, The Netherlands.

The publication of this thesis was financially supported by afdeling kindergeneeskunde LUMC, afdeling verloskunde LUMC, BMA B.V. (Mosos), Chiesi pharmaceuticals B.V., KARL STORZ Endoscopie Nederland B.V., Toshiba Medical Systems Nederland,

Vaco2Med en Vygon Nederland B.V.

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Neonatal hematological and biochemical complications

in TTTS and TAPS

Proefschrift ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,

volgens besluit van het College voor Promoties te verdedigen op dinsdag 13 juni 2017

klokke 13:45 uur

door

Lianne Irene Verbeek geboren te Rijswijk in 1990

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Promotoren: Prof. Dr. E. Lopriore

Prof. Dr. D. Oepkes

Leden promotiecommissie: Prof. Dr. A. Lankester Prof. Dr. C.M. Fijnvandraat

Emma Children’s Hospital, Academic Medical Center,

Amsterdam,The Netherlands

Dr. A. Khalil

St George’s Medical School, University of London,

London, United Kingdom

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Contents

Chapter 1 General introduction 11

Hematological disorders

Chapter 2 Hematological disorders at birth in complicated 19 monochorionic twins

Expert Rev Hematol. 2016 Dec. In Press

Chapter 3 Hemoglobin differences in uncomplicated monochorionic 37 twins in relation to birth order and mode of delivery

Twin Res Hum Genet. 2016 Jun;19(3):241-5

Chapter 4 Hemoglobin discordances in twins: 49

due to differences in timing of cord clamping?

Arch. Dis Child. Fetal Neonatal Ed. 2016 Dec 9.

Biochemical disorders

Chapter 5 Hypoalbuminemia in donors with twin-twin transfusion syndrome 61 Fetal Diagn Ther. 2013;33(2):98-102

Chapter 6 Hypoalbuminemia in donors with twin anemia-polycythemia 71 sequence:a matched case-control study

Fetal Diagn Ther. 2013;33(4):241-5

Chapter 7 Short-term postnatal renal function in twin anemia-polycythemia 83

sequence

Fetal Diagn Ther. 2016;39(3):192-7

Chapter 8 Renal function in neonates with twin-twin transfusion syndrome 95 treated with or without fetoscopic laser surgery

Submitted

Chapter 9 General discussion and future perspectives 107

Chapter 10 Summery/samenvatting 121

Chapter 11 Appendices 133

List of abbreviations Authors and affiliations

Dankwoord (acknowledgements) Publications

Curriculum vitae

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