Cover Page
The handle http://hdl.handle.net/1887/80956 holds various files of this Leiden University dissertation.
Author: Gaag, K.J. van der
Title: Development of forensic genomics research toolkits by the use of Massively
Parallel Sequencing
Development of forensic genomics research toolkits
by the use of Massively Parallel Sequencing
Development of forensic genomics research toolkits by the use of Massively Parallel Sequencing
The research described in this thesis was financially supported by the Leiden University Medical Center and by a grant from the Netherlands Genomics Initiative / Netherlands Organization for Scientific Research (NWO) within the framework of the Forensic Genomics Consortium Netherlands
Author Kristiaan J. van der Gaag ISBN / EAN: 978-94-6332-585-1
Cover FDSTools visualisation (samplevis) of sequencing variation from 14 STR loci in a set of 300 dutch inidividuals Back cover FDSTools samplestats table
Layout & cover design Kristiaan van der Gaag and Jerry Hoogenboom © K.J. van der Gaag, 2019
Development of forensic genomics research toolkits
by the use of Massively Parallel Sequencing
Epilogue
Promotores Prof. dr. P. de Knijff Prof. dr. J.T. den Dunnen
Copromotor Dr. T. Sijen – Nederlands Forensisch Instituut
(NFI)
Leden promotiecomissie Prof. dr. D.J.M. Peters
Table of contents
Chapter 1: 9
Introduction / Outline Chapter 2 21
TSSV: a tool for characterization of complex allelic variants in pure and mixed genomes Chapter 3 65
Forensic Nomenclature for Short Tandem Repeats updated for sequencing Chapter 4 73
Massively Parallel Sequencing of Short Tandem Repeats – Population data and mixture analysis results for the PowerSeq™ system Chapter 5 129
FDSTools: A software package for analysis of massively parallel sequencing data with the ability to recognise and correct STR stutter and other PCR or sequencing noise Chapter 6: 181
