University of Groningen
Clinical application of near infrared fluorescence imaging in solid cancers
Voskuil, Floris
DOI:
10.33612/diss.151946702
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Publication date: 2021
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Voskuil, F. (2021). Clinical application of near infrared fluorescence imaging in solid cancers: Enhancing surgical accuracy by lighting up tumors. University of Groningen. https://doi.org/10.33612/diss.151946702
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CLINICAL APPLICATION OF NEAR INFRARED
FLUORESCENCE IMAGING IN SOLID CANCERS
I
mproving surgical accuracy by lighting up tumors
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Printing of this thesis was financially supported by the University of Groningen, the Graduate School of Medical Sciences of the University Medical Center Groningen, SurgVision, LI-COR Biosciences Inc., TRACER, ChipSoft, Noord Negentig, OncoNano Medicine Inc., Straumann Group, Dam Medical, Nobel Biocare, KNMT, NVMKA, Patiëntenvereniging HOOFD-HALS, Detact Diagnostics en PRA HealthSciences.
Printed by Ipskamp Printing
Enschede, the Netherlands
Design & layout Bianca Pijl, www.pijlldesign.nl Groningen, the Netherlands
© Copyright: 2021 F.J. Voskuil, Groningen, the Netherlands
All rights reserved. No part of this thesis may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, without prior written permission of the author, or when appropriate, of the publishers of the publications included in this thesis.
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Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties
De openbare verdediging zal plaatsvinden op woensdag 17 maart 2021 om 14.30 uur
door Floris Jan Voskuil
geboren op 10 september 1991 te Nieuwegein
CLINICAL APPLICATION OF NEAR INFRARED
FLUORESCENCE IMAGING IN SOLID CANCERS
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Promotores Dr. M.J.H. Witjes Prof. dr. G.M. van Dam Prof. dr. W.B. Nagengast
Beoordelingscommissie Prof. dr. R.A.J.O. Dierckx Prof. dr. S.M. Willems Prof. dr. R.P. Takes
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Paranimfen Dr. M.D. Voskuil Drs. M. van der Paauw
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7 Chapter 1 Chapter 2 Chapter 3 Chapter 4 Chapter 5 Chapter 6 Chapter 7 Chapter 8 Appendix 1 Appendix 2
General introduction and outline of the thesis
C-Met targeted fluorescence molecular endoscopy in Barrett’s esophagus patients and identification of outcome parameters for phase-I studies
Theranostics, 2020
The optimal imaging window for dysplastic colorectal polyp detection using c-Met targeted fluorescence molecular endoscopy
Journal of Nuclear Medicine, 2020
Fluorescence-guided imaging for resection margin evaluation in head and neck cancer patients using cetuximab-800CW:
A quantitative dose-escalation study
Theranostics, 2020
Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
Nature Communications, 2020
The current status and future perspectives of intraoperative imaging assisted pathology (IPAS), an uncharted application in precision oncology surgery
Accepted for publication in Nature Biomedical Engineering
Summary, general discussion and future perspectives
Summary in Dutch
About the author
Acknowledgements 9 21 45 65 91 123 153 169 177 185 Table of contents
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