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University of Groningen Production of novel protein therapeutics to improve targeted cancer therapy Al-Qahtani, Alanod

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Production of novel protein therapeutics to improve targeted cancer therapy Al-Qahtani, Alanod

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Al-Qahtani, A. (2019). Production of novel protein therapeutics to improve targeted cancer therapy. University of Groningen.

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229

Chapter 10:

Appendix

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231

Propositions

It is a continuous battle between science and nature, who is going to win the war?

Al-Anod D. Al-Qahtani

• “Man is either your brother in faith or your equal in humanity.”-Ali bin Abii Taleb. • “Only two things are infinite, the universe and human stupidity, and I'm not sure

about the universe.” - Albert Einstein

• “A person who never made a mistake, never tried anything new.”- Albert Einstein • “One, remember to look up at the stars and not down at your feet. Two, never give

up work. Work gives you meaning and purpose and life is empty without it. Three, if you are lucky enough to find love, remember it is there and don't throw it away.” - Stephen Hawking

• “There may be times when we are powerless to prevent injustice, but there must

never be a time when we fail to protest.”- Elie Wiesel

• “You do not write your life with words...You write it with actions. What you think is not important. It is only important what you do.”-Patrick Ness

• “The definition of insanity is doing the same thing over and over and expecting different results.”- Albert Einstein

• “Such studies might also open a rational pathway for further changes.” - this thesis • “modification can lead to slight denaturation which may generate a significant

immune response”- this thesis

• “If you genuinely believe it … It will happen. Just aim towards it.”- Myself • “If you are not doing what you love, you are wasting your time.”- Billy Joel • What nature have done in millions of years could be done in laboratories in several

days.- my view

• Science can beat nature and yield biobetter products than the wild type. – my view • Naturally lethal, but could be therapeutics. – my view

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• “Question and criticism yourself as if you are your worst enemy.”- Prof. Sayed Goda

• “If you want to worship God be good to all mankind first regardless their religions, skin colors or political beliefs then do the rest such as praying and others.” -Prof. Sayed Goda

• “Poverty and ignorance of peoples are the true wealth of the tyrants, dictators and terrorists, without which they cannot commit their crimes.” -Prof. Sayed Goda

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233

Conferences:

American Society for Biochemistry and Molecular Biology, 26-30 Apr. 2014, San

Diego, CA, USA. ( Poster presentation)

• The Medicinal Chemistry & Bioanalysis symposium (MCB 2014), 25-26Aug.

2014, Groningen, The Netherlands. (Poster presentation).

• American Society for Biochemistry and Molecular Biology, March 28- April 1,

2015, Boston, USA 2015( Poster presentation)

10th Annual Proteins & Antibodies Congress, 24- 25 Apr. 2017, London, UK (

Poster presentation)

• PEGS Europe Protein and antibody engineering summit 13-17 Nov. 2017,

Lisbon, Portugal ( Poster presentation)

Anti Doping Lab QATAR Annual Junior symposiums 2013, 2014, 2015, 2016,

and 2017, Doha, Qatar. ( Lecture)

AntiDoping Lab QATAR Annual Junior symposiums 2018, Doha, Qatar. (Poster

presentation)

Qatar Foundation Annual Research Conference, 2015, 2016 and 2017, Doha,

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Acknowledgment

ْﻢُﻜﱠﻧَﺪﯾ ِزَ َﻷ ْﻢُﺗْﺮَﻜَﺷ ﻦِﺌَﻟ

(If you are thankful, surely I will increase you)7 Ibrahim

Thank you Allah ﻞﺟو ﺰﻋ ﮫﻠﻟ ﺮﻜﺸﻟاو ﺪﻤﺤﻟا

To My Parents

Thank you for believing in me

Thank you for making it possible

Thank you for being my biggest supporters I

am nothing without you.

I truly give you both all my success

I would like to express my deep appreciation to my PhD supervisors,

Professor Sayed K Goda and Professor Alex Dömling

Thank you for your guidance, encouragement and critiques. Thank you for pushing me and believing in me, when I felt down and discouraged. Thank you for teaching me to be more than just a scientist, but to become a humble and intuitive person. You are both the best example of a true scientist. I would especially thank Dr Sayed for his persistence and patience with me. Thank you for teaching me that science is not only obtaining a degree, but it’s a life style and a plan for the future. I thank you for being a father figure to me. I can loudly say:

Dr. Sayed you are my Guru.

I would like to thank my sister (Noora), and my brothers (Ahmad, Hamad, &

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To my daughter, my beautiful baby, my pride and joy, my princess

(Maryam)

It is you who made me realize that I have to do my best to be your best. It is you who made me wake up and realize that I can be more than just a mother.

To (Prof, David O’Conner) I can’t thank him enough for making the time to proof read my papers, even though he is very busy, he managed go through them and criticism it as if they were his own.

I would like to thank (Dr. Mohammad AlMaadeed) for initiating and supporting the PhD program in the ADL Q.

My appreciative thanks are also extended to (Dr. Matthew Groves). The first person in Groningen who was patient enough to stand with me hand in hand and teach me the basics and trick of molecule biology and always encouraging me to do better.

I would liket o thank (Dr.Mohammad AlSayrafi and Prof. Aisha Lattif) for their continuous support durning my PhD journey.

Our lab manager in GU, (André) Thank you for giving me your time in translating my English thesis summary to Dutch.

I would also like to extend my appreciations to both the Protein Engineering Lab especially Sara Bashraheel and the ADLQ as a whole and everyone in the Drug

Discovery Unit in GU. Both labs have become by second family, holding some of the

best memories between those walls.

I would like to give an exceptional thank you to my friends and loved ones without for being supportive, understanding and baring with me at all times.

I would like to acknowledge QNRF for funding and ADLQ for giving me a chance to work full time on my PhD.

After a journey of ups and downs and memories filled with mixed emotions, I can now stand proudly and say it was the best experience of my life. I am happy to have taken the initiative to make a difference in my life and add my part in the pool of science.

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