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University of Groningen Physiological and psychosocial occupational exposures and intermediate health outcomes in the general population Faruque, Md Omar

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University of Groningen

Physiological and psychosocial occupational exposures and intermediate health outcomes in

the general population

Faruque, Md Omar

DOI:

10.33612/diss.154938193

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Faruque, M. O. (2021). Physiological and psychosocial occupational exposures and intermediate health outcomes in the general population. University of Groningen. https://doi.org/10.33612/diss.154938193

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Physiological and psychosocial

occupational exposures and intermediate

health outcomes in the general population

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The publication of this thesis was supported by the University of Groningen, University Medical Center Groningen, and Graduate School of Medical Sciences (GSMS).

Cover design, illustrations, and layout by Md Omar Faruque Print: proefschriftmaken | https://www.proefschriftmaken.nl © M O Faruque 2020

All rights reserved. No part of this publication may be reproduced, copied, modified, stored in a retrieval system, or transmitted without the express written permission from the author, when appropriate, the publishers holding the copyrights of the published articles.

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Physiological and psychosocial occupational exposures and intermediate health outcomes in the general population

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the

Rector Magnificus Prof. C. Wijmenga and in accordance with the decision by the College of Deans. This thesis will be defended in public on Monday 25 January 2021 at 9:00 hours

by

Md Omar Faruque

born on 24 January 1983 in Natore, Bangladesh

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Supervisors Prof. H.M. Boezen Prof. U. Bültmann Co-supervisor Dr. J.M. Vonk Assessment Committee Prof. V. Schlünssen Prof. A. Timmer Prof. H.A.M. Kerstjens

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Paranymphs

L.A. Hoveling N.G. Asefa

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Table of Contents Page

Chapter 1 General introduction 9

Chapter 2 Occupational exposures and genetic susceptibility to occupational exposures are related to sickness absence

in the Lifelines Cohort Study 19

Chapter 3 Airborne Occupational Exposures and Lung Function in

the Lifelines Cohort Study 51

Chapter 4 Airborne occupational exposures and inflammatory biomarkers in the Lifelines Cohort Study 99

Chapter 5 Occupational exposures and the development of respiratory symptoms and airway obstruction 109

Chapter 6 Psychosocial work factors and blood pressure among 63,800 employees from the Netherlands in the Lifelines

Cohort Study 131

Chapter 7 Summary, general discussion, and future perspectives 157

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