University of Groningen
Magnetic Nanoparticles for the Control of Infectious Biofilms Quan, Kecheng
DOI:
10.33612/diss.170829667
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date: 2021
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Quan, K. (2021). Magnetic Nanoparticles for the Control of Infectious Biofilms. University of Groningen. https://doi.org/10.33612/diss.170829667
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
Propositions “Magnetic Nanoparticles for the Control of Infectious Biofilms’’ Kecheng Quan
1. Distribution of antimicrobials through a biofilm affects their killing efficacy towards its inhabiting bacteria.(This thesis)
2. Precise magnetic targeting of nanoparticles to a micrometer-sized infection site cannot be achieved under clinical conditions. (This thesis)
3. Water-filled channels only transport limited amounts of nutrients, waste-products and antimicrobials in a biofilm. (This thesis)
4. Artificial channels can be created by magnetically-driven movement of magnetic nanoparticles in a biofilm to enhance
antimicrobial penetration without the need of sophisticated, precise magnetic targeting systems. (This thesis)
5. Interaction between polydopamine modified magnetic
nanoparticles and bacteria prevents antimicrobial penetration into a biofilm after magnetically-driven channels digging. (This thesis) 6. Magnetic nanoparticles attached to an implant surface can be pulled off on-demand to increase the penetrability of biomaterial-associated infectious biofilms to antimicrobials without the need of precise targeting. (This thesis)
7. An experiment and a baby have things in common.
8. Being bored, struggled and desperate are necessities for achieving success.
9. Dreams provide direction for moving forward in life.
10. Every small success in the pursuit of a PhD degree is a stimulus to continue.
