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VU Research Portal

Bones in balance

Vlot, M.C.

2020

document version

Publisher's PDF, also known as Version of record

Link to publication in VU Research Portal

citation for published version (APA)

Vlot, M. C. (2020). Bones in balance: use of bone turnover markers in clinical practice.

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Table of Contents

Part I Introduction

Chapter 1 General introduction 13

Chapter 2 Clinical utility of bone markers in various diseases 25

Part II Effects of sex steroids on bone health in transgender persons

Chapter 3 Effect of pubertal suppression and cross-sex hormone therapy on 57 bone turnover markers and bone mineral apparent density (BMAD) in

transgender adolescents

Chapter 4 Bone mineral density increases in trans persons after 1 year of 77 hormonal treatment: a multicenter prospective observational study

Chapter 5 Gender-affirming hormone treatment decreases bone turnover in 95 trans women and older trans men

Part III Effects of inflammation and auto-immune disease on bone turnover

Chapter 6 Effect of antiretroviral therapy on bone turnover and bone mineral 117 density in men with primary HIV-1 infection

Chapter 7 Multiple sclerosis patients show lower bioavailable 25(OH)D and 131

1,25(OH)2D, but no difference in ratio of 25(OH)D/24,25(OH)2D and

FGF23 concentrations

Part IV Possible role of FGF23 as tumor marker in malignant disease

Chapter 8 Plasma FGF23 is not elevated in prostate cancer 153

Part V Summary and discussion

Chapter 9 Summary and discussion (English and Dutch) 163

Part VI Appendices

List of publications 185

Contributing authors and affiliations 187

Portfolio 190

About the author 194

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