Cover Page
The handle http://hdl.handle.net/1887/48097 holds various files of this Leiden University dissertation.
Author: Schaafsma , B.E.
Title: Near-infrared image guidance in cancer surgery
Issue Date: 2017-04-19
Chapter 4
Clinical trial of combined radio- and
uorescence-guided sentinel lymph node biopsy in breast cancer
British Journal of Surgery 2013;100:1037-1044
ABSTRACT
Background
Methods
Results
Conclusion
INTRODUCTION
METHODS
Tracer preparation
Study design
Statistical analysis
RESULTS
Fig. 1. Patient enrolment.
Fig. 2. Near-infrared (NIR) uorescence imaging during sentinel lymph node (SLN) mapping in breast cancer.
Sentinel lymph node detection Table 1.
Characteristic Low-dose group
(16 patients)
High-dose group (16 patients)
P
N N
Characteristic Total (32 patients)
Low-dose (16 patients)
High-dose (16 patients)
P
N N N
Fig. 3. Intraoperative detection of lymphatic vessels using near-infrared (NIR) uorescence imaging.
Table 2.
Comparison between treatment groups
Fig. 4. I