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The handle http://hdl.handle.net/1887/48097 holds various files of this Leiden University dissertation.

Author: Schaafsma , B.E.

Title: Near-infrared image guidance in cancer surgery

Issue Date: 2017-04-19

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Introduction:  e clinical use of near- infrared uorescence imaging for image- guided oncologic procedure or treatment evaluation

Adapted from

Journal of Surgical Oncology 2011;104:323-332

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INTRODUCTION

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Table I.

Imaging system Excitation source Working

distance Field of view White light illumination of

surgical eld

NIR-colour overlay

Fig. 1. Chemical and optical characteristics of ICG: A.

B.

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NIR FLUORESCENCE IMAGING

Clinically available NIR imaging systems

Indocyanine green

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SENTINEL LYMPH NODE MAPPING

Breast cancer

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Fig. 2. Near-infrared uorescence sentinel lymph node mapping:

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Gastro-intestinal cancer

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Conclusions sentinel lymph node mapping

TUMOUR IMAGING

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Fig. 3. ICG uptake and retention in liver tumours:

Imaging of hepatobiliary cancer

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Marking tumours

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Other solid tumours

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CONCLUSION AND OUTLINE OF THE THESIS

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