University of Groningen
Quantifying the transcriptome of a human pathogen
Aprianto, Rieza
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Publication date:
2018
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Aprianto, R. (2018). Quantifying the transcriptome of a human pathogen: Exploring transcriptional
adaptation of Streptococcus pneumoniae under infection-relevant conditions. Rijksuniversiteit Groningen.
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Propositions Stellingen Belonging to the thesis Behorende bij het proefschrift
Quantifying the transcriptome of a human pathogen
1. The many transcriptional start sites allows pervasivetranscription of the dense pneumococcal genome (Chapter 2,
this thesis).
2. We went fishing in the co-expression matrix and caught a new competence gene (Chapter 3, this thesis).
3. Visualizing early infection is straightforward with brightly fluorescent pneumococci (Chapter 4, this thesis).
4. Host-pathogen dual RNA-seq enables researchers to
simultaneously hunt two targets and catching both; it has the potential to elucidate even more complex models, with more agents (Chapter 5, this thesis).
5. If I have seen further, it is by standing on the shoulders of giants who came before me (Bernard of Chartres, Isaac Newton).
6. Completing a doctoral study is 0.361 part of Herculean labors (this thesis).
7. Every question should be googled; one does not need to reinvent the wheel (this thesis).
8. Di mana bumi dipijak, di situ langit dijunjung. (which ever earth you stand on, there you uphold the sky, lit. trans.) 9. If you are not astonished by it, then you don’t understand it
(adapted from Niels Bohr).
10. Two things presist: typographical mistakes (typos) and glitter. 11. Flavors of reality serve distinct purposes: the Theory of
Evolution, an objective reality, fails to imbue meaning to our existence yet the Creation Story, an intersubjective reality, fails to explain biology.
