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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

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My dopamine has been busy: Research on gene by environment interactions in

child externalizing behavior

Chhangur, R.R.

Publication date

2016

Document Version

Final published version

Link to publication

Citation for published version (APA):

Chhangur, R. R. (2016). My dopamine has been busy: Research on gene by environment

interactions in child externalizing behavior.

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Research on GenE by Environment Interactions in child Externalizing Behavior

Rabia Chhangur

my dopamine has been busy

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Rabia Chhangur

my dopamine has been busy

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ISBN: 978-94-6299-385-3

Cover & book design: studio ilse van klei / www.ilsevanklei.nl Printed by: Ridderprint B.V., Ridderkerk, The Netherlands

Copyright © 2016 Rabia R. Chhangur

No part of this thesis may be reproduced in any form without permission from the author

MY DOPAMINE HAS BEEN BUSY

Research on Gene by Environment Interactions in Child

Externalizing Behavior

ACADEMISCH PROEFSCHRIFT

ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam op gezag van de Rector Magnificus prof. dr. ir. K.I.J. Maex ten overstaan van een door het College van Promoties ingestelde commissie, in het openbaar te verdedigen in de Aula der Universiteit op woensdag 5 oktober 2016, te 13.00 uur door Rita Rabiagatoen Chhangur geboren te Paramaribo, Suriname

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PROMOTIECOMMISSIE:

Promotores: Prof. dr. G. Overbeek, Universiteit van Amsterdam

Prof. dr. W. Matthys, Universiteit Utrecht Prof. dr. B. Orobio de Castro, Universiteit Utrecht

Overige leden: Prof. dr. M. J. Bakermans-Kranenburg, Universiteit Leiden

Prof. dr. S. M. Bögels, Universiteit van Amsterdam

Prof. dr. L. Goossens, Katholieke Universiteit Leuven

Prof. dr. P. J. M. Prins, Universiteit van Amsterdam

Prof. dr. G. J. J. M. Stams, Universiteit van Amsterdam

Faculteit der Maatschappij- en Gedragswetenschappen

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C0ntents

CHApter 1

– General Introduction

CHApter 2

DRD4 and DRD2 Genes, Parenting, and

Adolescent Delinquency: Longitudinal Evidence for a Gene by Environment Interaction

CHApter 3

– ORCHIDS: An Observational Randomized

Controlled Trial on Childhood Differential Susceptibility

CHApter 4

– Gene by Environment Research to Prevent

Externalizing Problem Behavior: Ethical Questions Raised for a Public Healthcare Perspective

CHApter 5

– Intervention Effectiveness of The Incredible

Years: New insights into Sociodemographic and Intervention-based Moderators

CHApter 6

– Genetic Moderation of Intervention Efficacy:

Dopaminergic Genes, The Incredible Years, and Externalizing Behavior in Children

CHApter 7

– Genetic Moderation of Intervention Efficacy:

Distinguishing Receptor-, Transporter-, and Enzyme-Related Dopaminergic Genes

CHApter 8

– General Discussion

References Summary Nederlandse Samenvatting Publications Dankwoord Curriculum Vitae 9 19 41 53 67 93 117 131 142 166 170 176 178 182

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