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University of Groningen Identification and characterization of flavoprotein monooxygenases for biocatalysis Gran Scheuch, Alejandro

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University of Groningen

Identification and characterization of flavoprotein monooxygenases for biocatalysis

Gran Scheuch, Alejandro

DOI:

10.33612/diss.154338097

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Gran Scheuch, A. (2021). Identification and characterization of flavoprotein monooxygenases for biocatalysis. University of Groningen. https://doi.org/10.33612/diss.154338097

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Propositions

accompanying the thesis

Identification and characterization of flavoprotein monooxygenases for

biocatalysis

by

Alejandro Gran Scheuch

1. (Micro)organisms that can survive extreme conditions do not always (only) harbor robust biocatalysts.

2. Metagenomes are an incredibly rich source of untapped biosynthetic dark matter. However, greater rigor is needed in describing the sampling conditions.

3. The dissociation of the caged radical pair in flavoprotein oxidases and monooxygenases is governed through a pH-sensitive mechanism.

4. ROS-production by flavoproteins is an inevitable biological process caused by electron leaking.

5. Not every yellow protein is a flavoprotein.

6. Chile contains a wide variety of extreme environments that should be further exploited for the development of biotechnology in the region.

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This work was supported by the Institute for Biological and Medical Engineering from Pontificia Universidad Católica de Chile and CORFO’s grant 14ENI2-26862. scholarship from