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Allogeneic haematopoietic stem cell donation and transplantation across the MHC class I barrier: "Faster is better than more. More is better than less".

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Allogeneic haematopoietic stem cell donation and transplantation

across the MHC class I barrier: "Faster is better than more. More is

better than less".

Heemskerk, M.B.A.

Citation

Heemskerk, M. B. A. (2006, September 28). Allogeneic haematopoietic stem cell donation and transplantation across the MHC class I barrier: "Faster is better than more. More is better than less". Retrieved from https://hdl.handle.net/1887/4578

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in theInstitutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/4578

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The HistoCheck algorithm does not predict T cell

alloreactivity in vitro.

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The HistoCheck algorithm does not predict T cell alloreactivity in vitro.

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Figure 1. The relation between the SSM score of donor/patient couples with a single HLA-A or -B allele mismatch and T cell alloreactivity in vitro (CTLp/106 PBL). The number of pairs in each group: 12 within the group with

an undetectable CTLp frequency and 23 within the group with detectable CTLp frequency. Horizontal lines indicate the mean of each group. No difference was found for HLA-A and -B mismatches (p = 0.54).

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Figure 2. The relation between the SSM score of donor/patient couples with a single HLA-C allele mismatch and T cell alloreactivity in vitro (CTLp/106

PBL). The number of pairs in each group: 24 within the group with an

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Allogeneic haematopoietic stem cell donation and transplantation across the MHC class I barrier: &#34;Faster is better than more.. More is better