University of Groningen
Controlling the self-assembly of amphiphiles using DNA G-quadruplexes
Cozzoli, Liliana
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Publication date:
2018
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Cozzoli, L. (2018). Controlling the self-assembly of amphiphiles using DNA G-quadruplexes. University of
Groningen.
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STELLINGEN
Behorende bij het proefschrift
Controlling the self-assembly of amphiphiles using DNA G-quadruplexes
1. The modular and predictable nature of DNA makes it an excellent building block to control the self-assembly of amphiphiles. However, the presence of a lipid moiety attached to an oligonucleotide can affect the DNA assembly as well (Chapter 2 of this thesis).
2. The introduction of multiple domains in the design of molecular aptamer beacons (MABs) can be a counter-productive strategy. A minimal design is often more effective to achieve a responsive system (Chapter 3 of this thesis).
3. If you want the rainbow, you have to deal with the rain’ (John Green in the
Fault in our Stars). That’s why the Netherlands is the perfect place where to do a PhD.
4. Working on different projects during the PhD reduces the feeling of frustration: when one of them is not going well, you can switch to the other one (at least until it still works).
5. The lab journal is the window to the soul of a scientist.
6. Working on an interdisciplinary project can be as frustrating as it is motivating. You realize your limitations, but this stimulates you to find a way to overcome them.
7. Writing the PhD thesis is possibly the most difficult step of the whole PhD journey; therefore, both the supervisor and the student should plan this step wisely, before the end of the contract.