University of Groningen Air pollution exposure of lung models Cattani Pinto Cavalieri, Isabella

(1)

University of Groningen

Air pollution exposure of lung models Cattani Pinto Cavalieri, Isabella

DOI:

10.33612/diss.172080794

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Cattani Pinto Cavalieri, I. (2021). Air pollution exposure of lung models: focus on inflammation, oxidative stress and cyclic AMP signaling. University of Groningen. https://doi.org/10.33612/diss.172080794

Copyright

Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).

Take-down policy

If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.

Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

(2)

Air pollution exposure of lung

models:

Focus on inflammation, oxidative stress and

cyclic AMP signaling

(3)

The studies described in this thesis were performed within the framework of Molecular Pharmacology Department of University of Groningen and Institute of Biomedical Sciences, Federal University of Rio de Janeiro, and was financially supported by Brazilian Federal Agency for Support and Evaluation of Graduate Education (CAPES), Carlos Chagas Filho Foundation for Research Support in the State of Rio de Janeiro (FAPERJ).

The research work was carried out according to the requirements of the Graduate School of Science, Faculty of Science and Engineering, University of Groningen, The Netherlands.

Printing of this thesis was financially supported by the University Library and the Graduate School of Science, Faculty of Science and Engineering, University of Groningen, The Netherlands.

Cover image by PNGTREE

Printed by Ipskamp Printing, proefschriften.net

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, by photocopying, recording, or otherwise, without the prior written permission of the author.

(4)

Air pollution exposure

of lung models:

Focus on inflammation, oxidative stress and

cyclic AMP signaling

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the

Rector Magnificus Prof. C. Wijmenga and in accordance with

the decision by the College of Deans. This thesis will be defended in public on

Monday 14 June 2021 at 18.00 hours

by

Isabella Cattani Pinto Cavalieri born on 28 September 1989

(5)

Supervisors Prof. M. Schmidt Prof. S.S Valença

Assessment Committee Prof. B.N. Melgert

Prof. H.I. Heijink Prof. F.R. Cassee Prof. C. F. Benjamim

(6)

Paranymphs:

Angélica Maria Sabogal Guáqueta

Asmaa Oun

(7)

(8)

University of Groningen Air pollution exposure of lung models Cattani Pinto Cavalieri, Isabella

Air pollution exposure of lung

models:

Focus on inflammation, oxidative stress and

cyclic AMP signaling

Air pollution exposure

of lung models:

Focus on inflammation, oxidative stress and

cyclic AMP signaling

Contents