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Immunological challenges during pregnancy : preeclampsia and egg donation Hoorn, M.L. van der

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Citation

Hoorn, M. L. van der. (2012, January 11). Immunological challenges during pregnancy : preeclampsia and egg donation. Retrieved from

https://hdl.handle.net/1887/18330

Version: Corrected Publisher’s Version License:

Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/18330

Note: To cite this publication please use the final published version (if

applicable).

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Immunological challenges during pregnancy

Preeclampsia and Egg Donation

Marie-Louise van der Hoorn

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Immunological challenges during pregnancy

Preeclampsia and Egg Donation

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magniicus prof.mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op woensdag 11 januari 2012

klokke 16.15 uur

door

Marie-Louise Petronella van der Hoorn

geboren te Langeraar in 1983

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Prof. dr. E.A.P. Steegers Erasmus Universiteit Rotterdam

© 2012 M.L.P. van der Hoorn, Leiden, The Netherlands

Immunological challenges during pregnancy; preeclampsia and egg donation

The research described in this thesis was performed at the department of Immunohematology and Blood Transfusion and the department of Obstetrics at the Leiden University Medical Center, Leiden, The Netherlands.

ISBN

Cover and layout: Marie-Louise van der Hoorn

Four pregnancies which colored this thesis; preeclamptic, normal, ivf and egg donation pregnancies.

Printed by: Off page.nl

Financial support for the publication of this thesis was kindly provided by: Beckman Coulter BV, BMA BV (Mosos), Clean Air Techniek BV, Corning BV, Freya; vereniging voor mensen met vruchtbaarheidsproblemen, Greiner Bio-One, J.E. Juriaanse Stichting, Medical Dynamics, Memidis Pharma BV, Nationaal Referentie Centrum voor Histocompatibiliteit, Rabobank Medicidesk, Stichting HELLP-syndroom, Stichting Oranjekliniek and VPS Diagnostics.

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Introduction

Changes in cytokine production and composition of peripheral blood leukocytes during pregnancy are not associated with a diff erence in the proliferative immune response to the fetus

Human Immunology 2011;72:805-811

Diff erential distribution and phenotype of decidual macrophages in preeclamptic versus control pregnancies

The American Journal of Pathology 2011;178(2):709-17

Preeclampsia in non donor IVF and egg donation pregnancy:

is there a diff erent pathophysiology?

Fertility and Sterility 2011;95(2):805 e1-3

Nederlands Tijdschrift voor Geneeskunde 2010;154:A1982

Egg donation pregnancy as an immunological model for solid organ transplantation

Transplant Immunology 2011;25(2-3):89-95

Clinical and immunologic aspects of egg donation pregnancies:

a systematic review

Human Reproduction Update 2010;16(6):704-12

Diff erential immunoregulation in successful oocyte donation pregnancies compared with naturally conceived pregnancies

Submitted paper

Summary and general discussion

Nederlandse samenvatting Publications

Curriculum Vitae Dankwoord Abbreviations Chapter 1

Chapter 2

Chapter 3

Chapter 4

Chapter 5

Chapter 6

Chapter 7

Chapter 8

Chapter 9

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