Basic and clinical aspects of mucosal inflammation and healing in Crohn's disease

The work described in this thesis was performed at the department of Clinical Epidemiology at the Leiden University Medical Center in Leiden, the Netherlands and at the department

Control group: Blood samples without LPS stimulation were incubated with 0.9% NaCl, at an equal volume to LPS and/or infliximab solutions under the same

This preliminary study revealed that the healing of fistulas in CD by treatment with infliximab is accompanied by a decrease in serum bFGF levels, whereas the

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[28] did not find epithelial cell or extracellular matrix staining in normal colonic mucosa, but found that immunoreactivity for bFGF was particularly present at the

In the mucosal inflammation of the intestine, the intestinal epithelial cell not only processes the antigens but also actively participates, together with other non-immune

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/850..

The work described in this thesis was performed at the department of clinical epidemiology, Leiden University Medical Center, Leiden, the Netherlands, and the Cardiovascular