University of Groningen
Towards an optimal clinical protocol for the treatment of moving targets with pencil beam
scanned proton therapy
Ribeiro, Cássia O.
DOI:
10.33612/diss.126443635
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from
it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date:
2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Ribeiro, C. O. (2020). Towards an optimal clinical protocol for the treatment of moving targets with pencil
beam scanned proton therapy. University of Groningen. https://doi.org/10.33612/diss.126443635
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
Stellingen behorend bij het proefschrift
TOWARDS AN OPTIMAL CLINICAL PROTOCOL
FOR THE TREATMENT OF MOVING TARGETS
WITH PENCIL BEAM SCANNED
PROTON THERAPY
1. The use of multiple deformable image registration algorithms is a valuable strategy to reduce the uncertainty for inter- fractional dosimetric evaluation during lung cancer proton treatment. (This thesis)
2. Dosimetric errors induced by deformable image registration indicate the necessity to interpret individual 4D dose distri-butions for pencil beam scanned proton plans ideally with an error bar. (This thesis)
3. The establishment of optimal clinical protocols requires com-prehensive 4D evaluations of pencil beam scanned proton therapy for moving targets. (This thesis)
4. Although 3D robust optimised proton planning proved to be sufficient for most thoracic indications, accurate patient posi-tioning and adapting to anatomical variations over the course of treatment remain compulsory. (This thesis)
5. Clinically acceptable robust plans can be achieved for moving targets treated with Proteus®Plus, as well as with Proteus®One
proton scanning technologies. (This thesis)
6. Uncertainties in treating moving targets with protons are in-evitable. We need to know how to deal with them.
7. Intelligence is the ability to adapt to change. (Stephen Hawking) 8. A man is a success if he gets up in the morning and goes to
bed at night, and in between he does what he wants to do. (Bob Dylan)
9. It’s not the years in your life that count. It’s the life in your years. (Abraham Lincoln)
10. Happiness is not something readymade. It comes from your own actions. (Dalai Lama)
