Cover Page
The handle http://hdl.handle.net/1887/19858
holds various files of this Leiden University dissertation.
Author: Dikken, Johannes Leen
Title: Gastric cancer : staging, treatment, and surgical quality assurance Issue Date: 2012-09-26
phd thesis
leiden university medical center, leiden, the netherlands netherlands cancer institute - antoni van leeuwenhoek hospital, amsterdam, the netherlands
memorial sloan-kettering cancer center, new york, usa
Promotiecommissie
promotores
prof. dr. C.J.H. van de Velde
prof. dr. M. Verheij Nederlands Kanker Instituut
- Antoni van Leeuwenhoek Ziekenhuis
Vrije Universiteit Amsterdam
co-promotores
dr. A. Cats Nederlands Kanker Instituut
- Antoni van Leeuwenhoek Ziekenhuis
dr. V.E.P.P. Lemmens Integraal Kankercentrum Zuid
Erasmus Medisch Centrum
overigeleden
prof. dr. H. Putter
prof. dr. R.A.E.M. Tollenaar
dr. N.C.T. van Grieken VU Medisch Centrum dr. J.W. van Sandick Nederlands Kanker Instituut
- Antoni van Leeuwenhoek ziekenhuis
drs. M.W.J.M. Wouters Nederlands Kanker Instituut
- Antoni van Leeuwenhoek ziekenhuis
ditproefschriftwerdmedemogelijkgemaaktdoor
KWF Kankerbestrijding, AngioDynamics, Bard Medical, ChipSoft, Covidien, Eli Lilly, Erbe, GlaxoSmithKline, Integraal Kankercentrum Zuid, J.E. Jurriaanse Stichting, Johnson & Johnson Medical, Jo Keur Fonds, Lustra Beurs, Maag Lever Darm Stichting, Michael van Vloten Fonds, Nutricia Advanced Medical Nutrition, Olympus, Pfizer, Roche, Sanofi, Stichting Extracurriculaire Activiteiten Haagse Chirurgen en Uitgeverij Jaap ISBN 978 90 6464 574 7
Druk GVO drukkers & vormgevers B.V. | Ponsen & Looijen
© 2012 Johan Dikken, Leiden, Nederland
gastric cancer
staging, treatment, and surgicalquality assurance
PROEFSCHRIFT ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties te verdedigen op woensdag 26 september 2012
klokke 16.15 uur
door
Johannes Leen Dikken geboren te Apeldoorn in 1983
contents
introduction
1. General introduction and outline of this thesis
parti. stagingandprognostication
2. The new American Joint Committee on Cancer/International Union Against Cancer staging system for adenocarcinoma of the stomach:
increased complexity without clear improvement in predictive accuracy
Annals of Surgical Oncology 2012
3. Prospective impact of tumor grade assessment in biopsies on tumor stage and prognostic grouping in gastroesophageal adenocarcinoma:
relevance of the 7th edition AJCC staging manual revision Cancer 2012
4. Conditional probability of survival nomogram for one, two, and three year survivors after an R0 resection for gastric cancer
Annals of Surgical Oncology 2012
5. Performance of a nomogram predicting disease-specific survival after an R0 resection for gastric cancer in patients receiving postoperative chemoradiotherapy
Submitted
partii. multimodalitytreatment
6. Treatment of resectable gastric cancer Therapeutic Advances in Gastroenterology 2012
7. Impact of the extent of surgery and postoperative chemoradiotherapy on recurrence patterns in gastric cancer
Journal of Clinical Oncology 2010
8. Preoperative chemotherapy does not influence the number of evaluable lymph nodes in resected gastric cancer
European Journal of Surgical Oncology 2012
9. Neo-adjuvant chemotherapy followed by surgery and chemotherapy or by surgery and chemoradiotherapy for patients with resectable gastric cancer (CRITICS)
BMC Cancer 2011
7
15
31
45
59
73
99
115
131
partiii. surgicalqualityassurance
10. Quality of care indicators for the surgical treatment of gastric cancer:
a systematic review
Annals of Surgical Oncology 2012
11. Increased incidence and survival for esophageal cancer but not for gastric cardia cancer in the Netherlands
European Journal of Cancer 2012
12. Gastric cancer: decreasing incidence but stable survival in the Netherlands
Submitted
13. Changes in treatment patterns and their influence on short-term mortality and long-term survival in patients with stage I-III gastric cancer in the Netherlands
Submitted
14. Effect of hospital volume on postoperative mortality and survival after esophageal and gastric cancer surgery in the Netherlands between 1989 and 2009
European Journal of Cancer 2012
15. The influence of hospital type on outcomes after esophageal and gastric cancer surgery
British Journal of Surgery 2012
16. Differences in outcomes of esophageal and gastric cancer surgery across Europe
British Journal of Surgery 2012
discussion
17. General discussion and summary
appendices
Summary in Dutch (Nederlandse samenvatting) Acknowledgements (Dankwoord)
List of publications Curriculum vitae
147
173
187
199
213
229
243
261
279 284 286 289
