University of Groningen
Probiotic Bacteria and Their Encapsulation Evaluated in Advanced Co-culture Models Yuan, Lu
DOI:
10.33612/diss.160691131
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Publication date: 2021
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Yuan, L. (2021). Probiotic Bacteria and Their Encapsulation Evaluated in Advanced Co-culture Models. University of Groningen. https://doi.org/10.33612/diss.160691131
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Probiotic Bacteria and Their Encapsulation
Evaluated in
Advanced Co-culture Models
Probiotic bacteria and their encapsulation evaluated in advanced co-culture models
University Medical Center Groningen, University of Groningen Groningen, The Netherlands
Cover artwork: Lu Yuan Layout: Lu Yuan
Printing: Ipskamp Printing B.V. Copyright © 2021 by Lu Yuan
Probiotic bacteria and their encapsulation
evaluated in
advanced co-culture models
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the
Rector Magnificus Prof. C. Wijmenga and in accordance with
the decision by the College of Deans. This thesis will be defended in public on Monday 22 March, 2021 at 14.30 hours
by
Lu Yuan
born on 04 August 1990 in Sichuan, China
Supervisors
Prof. H. C. van der Mei Prof. H. J. Busscher
Co-supervisors
Dr. B. W. PetersonAssessment Committee
Prof. P. de Vos Prof. Y. Ren Prof. Y. WeiParanimfen:
Huaiying Zhang Yangyang Guo
Table of Contents
Chapter 1 General Introduction and Aim of the
Thesis
1
Chapter 2 Two-stage Interpretation of Changes in
TEER of Intestinal Epithelial Layers
Protected by Adhering Bifidobacteria
during E. coli Challenges
Frontiers in Microbiology, 2020, 11: 599555
doi:10.3389/fmicb.2020.599555
15
Chapter 3 Visualization of Bacterial Colonization
and Cellular Layers in a Gut-on-a-Chip
System Using Optical Coherence
Tomography
Microscopy and Microanalysis 2020, 26: 1211-1219
doi:10.1017/S143192762002454X
47
Chapter 4 Escherichia coli Colonization of Intestinal
Epithelial Layers In Vitro in the Presence
of Encapsulated Bifidobacterium breve
for its Protection against
Gastro-intestinal Fluids and Antibiotics
Submitted to ACS Applied Materials & Interface, 2020