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University of Groningen MicroRNA expression and functional analysis in Hodgkin lymphoma Yuan, Ye

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University of Groningen

MicroRNA expression and functional analysis in Hodgkin lymphoma Yuan, Ye

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Yuan, Y. (2019). MicroRNA expression and functional analysis in Hodgkin lymphoma. University of Groningen.

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Stellingen

Behorende bij het proefschrft

MicroRNA expression and functional analysis in Hodgkin

lymphoma

1. Most of the miRNAs highly abundant in germinal center B cells are also highly abundant in Hodgkin lymphoma (This thesis).

2. MiR-24-3p functions as an oncogenic miRNA in Hodgkin lymphoma and targets CDKN1B/P27kip1 (This thesis).

3. High-throughput microRNA inhibition screenings allow efficient

identification of miRNAs that affect growth of Hodgkin lymphoma cells (This thesis).

4. High-throughput miRNA overexpression screening revealed potential

growth regulatory roles of miR-19b-1 and miR-141 (This thesis).

5. MiR-21-5p protects Hodgkin lymphoma cells from apoptosis possibly via targeting BTG2 and PELI1 (This thesis).

6. Immunoprecipitation (IP) with an anti-Ago2 antibody is an effective approach to identify Hodgkin lymphoma relevant miRNA target genes (This thesis).

7. Non-coding RNAs can be used as prognostic markers, biomarkers, or as

therapeutic targets (Navarro et al., 2017).

8. What you sow, you reap. 种瓜得瓜, 种豆得豆 (《涅盘经》).

9. Cherish to own, gratitude can last forever. 珍惜才能拥有,感恩才能天长地

久.

10. If you don’t challenge yourself, you will never realize what you can become (Unknown).

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