Neonatal management and outcome in red cell alloimmunization
Smits-Wintjens, V.E.H.J.
Citation
Smits-Wintjens, V. E. H. J. (2012, February 15). Neonatal management and outcome in red cell alloimmunization. Retrieved from
https://hdl.handle.net/1887/18485
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/18485
Note: To cite this publication please use the final published version (if applicable).
List of abbreviations Authors and affiliations
Curriculum Vitae Publications
Dankwoord
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List of abbreviations
AAP American Academy of Pediatrics BSID Bayley Scales of Infant Development CI Confidence interval
CP Cerebral palsy EPO Erythropoietin
ET(s) Exchange transfusion(s)
Hb Hemoglobulin
HDFN Hemolytic disease of the fetus/newborn HDN Hemolytic disease of the neonate/newborn IgG Immunoglobulin
IQR Interquartile range IUT(s) Intrauterine transfusion(s) IVIg Intravenous immunoglobulin
LIVIN Leiden’s IVIg trial in Rhesus disease of the Neonate LOTUS LOng-Term follow-up after intraUterine transfusionS LUMC Leiden University Medical Center
MDI Mental developmental index MND Minor neurological dysfunction NDI Neurodevelopmental impairment
OR Odds ratio
PT Phototherapy
RCT Randomized controlled trial
Rh Rhesus
Rh D Rhesus D
RHDN Rhesus hemolytic disease of the neonate/newborn SD Standard deviation
WISC Dutch version of Wechsler Intelligence Scale for Children
WPPSI Dutch version of Wechsler Preschool and Primary Scale of Intelligence
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Authors and affiliations
From the Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden:
Vivianne Smits-Wintjens, Mirjam Rath, Sylke Steggerda, Arjan te Pas, Frans Walther, Enrico Lopriore
From the Division of Fetal Medicine, Department of Obstetrics, Leiden University Medical Center, Leiden:
Irene Lindenburg, Dick Oepkes, Inge van Kamp, Jan van Lith, Humphrey Kanhai
From the Department of Immuno-Hematology and Blood Transfusion, Leiden University Medical Center, Leiden:
Anneke Brand, Esther Verduin, Henk Schonewille, Ilias Doxiadis
From the Department of Biostatistics, Leiden University Medical Center, Leiden:
Erik van Zwet
From the Department of Medical Psychology, Leiden University Medical Center, Leiden:
Jeanine van Klink
From Sanquin Blood Supply Foundation, Amsterdam:
Christine Kramer
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Curriculum Vitae
Vivianne Smits-Wintjens
Geboren op 17 februari 1972 te Maastricht
1984 - 1991 Gymnasium bèta, Sint Maartenscollege, Maastricht 1991 - 1998 Studie Geneeskunde, Rijksuniversiteit Groningen
1995 Wetenschapsstage afdeling Neonatologie, Landeskrankenhaus, Graz 1998 - 2000 AGNIO Kindergeneeskunde, Isala Klinieken, Zwolle
2000 - 2001 AGNIO Kinder-IC, Leids Universitair Medisch Centrum, Leiden 2001 - 2005 Opleiding Kindergeneeskunde,
Leids Universitair Medisch Centrum, Leiden (Prof. dr. J.M. Wit) Reinier de Graaf Gasthuis, Delft (dr. N. van der Lely)
2005 Chef de Clinique afdeling Kindergeneeskunde, Reinier de Graaf Gasthuis, Delft
2006 - 2009 Fellowship Neonatologie, Leids Universitair Medisch Centrum, Leiden (Prof. dr. F.J. Walther)
2006 - 2011 Promotieonderzoek (o.a. LIVIN studie), afdelingen Neonatologie en Verloskunde, Leids Universitair Medisch Centrum, Leiden
Vanaf 2009 Staflid Neonatologie, Leids Universitair Medisch Centrum, Leiden
168
Publications
1. Smits-Wintjens VEHJ, Rath MEA, Lindenburg ITM, Oepkes D, van Zwet EW, Walther FJ, Lopriore E. Cholestasis in neonates with red cell alloimmune hemolytic disease: inci- dence, risk factors and outcome.
Neonatology; In press
2. Lindenburg IT, Smits-Wintjens VE, van Klink JM, Verduin E, van Kamp IL, Walther FJ, Schonewille H, Doxiadis II, Kanhai HH, van Lith JM, van Zwet EW, Oepkes D, Brand A, Lopriore E; LOTUS study group. Long-term neurodevelopmental outcome after intrau- terine transfusion for hemolytic disease of the fetus/newborn: the LOTUS study.
Am J Obstet Gynecol 2011; Epub ahead of print.
3. Steggerda SJ, de Bruïne FT, Smits-Wintjens VE, Walther FJ, van Wezel-Meijler G. Ultrasound detection of posterior fossa abnormalities in full-term neonates.
Early Hum Dev 2011; Epub ahead of print.
4. Rath ME, Smits-Wintjens VE, Oepkes D, van Zwet EW, van Kamp IL, Brand A, Walther FJ, Lopriore E. Thrombocytopenia at birth in neonates with red cell alloimmune haemo- lytic disease.
Vox Sang 2011; Epub ahead of print.
5. Rath ME, Smits-Wintjens VE, Walther FJ, Lopriore E. Hematological morbidity and man- agement in neonates with hemolytic disease due to red cell alloimmunization.
Early Hum Dev 2011; 87(9):583-8.
6. Smits-Wintjens VE, Walther FJ, Rath ME, Lindenburg IT, te Pas AB, Kramer CM, Oepkes D, Brand A, Lopriore E. Intravenous immunoglobulin in neonates with rhesus hemolytic disease: a randomized controlled trial.
Pediatrics 2011; 127(4):680-6.
7. Rath ME, Smits-Wintjens VE, Lindenburg IT, Brand A, van Kamp IL, Oepkes D, Walther FJ, Lopriore E. Exchange transfusions and top-up transfusions in neonates with Kell haemolytic disease compared to Rh D haemolytic disease.
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8. Verduin EP, Lindenburg IT, Smits-Wintjens VE, van Klink JM, Schonewille H, van Kamp IL, Oepkes D, Walther FJ, Kanhai HH, Doxiadis II, Lopriore E, Brand A. Long-Term follow up after intra-Uterine transfusionS; the LOTUS study.
BMC Pregnancy Childbirth 2010; 10:77.
9. Van der Lugt NM, Smits-Wintjens VE, van Zwieten PH, Walther FJ.Short and long term outcome of neonatal hyperglycemia in very preterm infants: a retrospective follow-up study.
BMC Pediatr 2010;10:52.
10. Verheij GH, Te Pas AB, Witlox RS, Smits-Wintjens VE, Walther FJ, Lopriore E. Poor accuracy of methods currently used to determine umbilical catheter insertion length.
Int J Pediatr 2010;873167.
11. Rath ME, Smits-Wintjens VE, Lindenburg IT, Brand A, Oepkes D, Walther FJ, Lopriore E.
Top-up transfusions in neonates with Rh hemolytic disease in relation to exchange transfusions.
Vox Sang 2010;99(1):65-70.
12. Smits-Wintjens VEHJ, Steggerda SJ, Oepkes D, van Kamp IL, Kramer CM, Walther FJ, Lopriore E. Bacillus cereus cerebral abscesses in a term neonate with Rhesus haemolytic disease treated with exchange transfusion.
J Pediatr Inf Dis 2010; 5(3):277-280.
13. Verheij G, Smits-Wintjens V, Rozendaal L, Blom N, Walther F, Lopriore E. Cardiac arrhyth- mias associated with umbilical venous catheterisation in neonates.
BMJ Case Rep 2009; bcr04.2009.1778.
14 . Smits-Wintjens VE, Walther FJ, Lopriore E. Rhesus haemolytic disease of the newborn:
Postnatal management, associated morbidity and long-term outcome.
Semin Fetal Neonatal Med 2008 Aug;13(4):265-71.
15. Smits-Wintjens VE, Zwart P, Brand PL. Underlying cow’s milk protein intolerance in ex- cessively crying infants; desirable and undesirable effects of an elimination diet.
Ned Tijdschr Geneeskd 2000;144(48):2285-7.
Veel dank aan...
Mika en alle andere participerende kinderen en hun ouders
en iedereen die op een positieve manier heeft bijdragen om dit proefschrift tot iets moois te maken.
172
...sjoen op tied veerdig!
