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VU Research Portal

MicroRNAs in HPV-induced cervical cancer

Babion, I.

2020

document version

Publisher's PDF, also known as Version of record

Link to publication in VU Research Portal

citation for published version (APA)

Babion, I. (2020). MicroRNAs in HPV-induced cervical cancer: Triage markers for cervical screening and drivers of carcinogenesis.

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Chapter 1 General Introduction

PART I MiRNAs as Triage Markers in HPV-Based Cervical Screening

Chapter 2 A Strategy to Find Suitable Reference Genes for miRNA Quantitative PCR Analysis and its Application to Cervical Specimens

Chapter 3 Triage of High-Risk HPV-Positive Women in Population-Based Screening by miRNA Expression Analysis in Cervical Scrapes; a Feasibility Study

Chapter 4 Genome-Wide miRNA Analysis of HPV-Positive Self-Samples Yields Novel Triage Markers for Early Detection of Cervical Cancer

Chapter 5 Complementarity between miRNA Expression Analysis and DNA Methylation Analysis in hrHPV-Positive Cervical Scrapes for the Detection of Cervical Disease

PART II MiRNAs and Other Molecular Changes as Drivers of HPV-Induced Transformation

Chapter 6 Identification of Deregulated Pathways, Key Regulators, and Novel miRNA-mRNA Interactions in HPV-Mediated Transformation

TABLE OF CONTENT

9 39 41 75 99 121 139 141

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Chapter 7 MiR-9-5p Exerts a Dual Role in Cervical Cancer and Targets Transcription Factor TWIST1

Chapter 8 Altered miRNA-Processing Proteins in HPV-Induced Cancers

Chapter 9 Summary, Discussion, and Future Perspectives

ADDENDUM

Chapter 10 Nederlandse Samenvatting Chapter 11 Deutsche Zusammenfassung Chapter 12 List of Publications

Affiliations of Co-Authors

About the Author

Chapter 13 Dankwoord, Acknowledgment, Danksagung

171 197 217 235 237 245 256 258 260 263

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