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The handle http://hdl.handle.net/1887/18608 holds various files of this Leiden University dissertation.
Author: Wijnmaalen, Adrianus Pieter
Title: Substrate of ventricular tachycardia
Issue Date: 2012-03-22
Substrate of Ventricular Tachycardia
Adrianus P. Wijnmaalen
Substrate of Ventricular Tachycardia Adrianus P. Wijnmaalen
The studies described in this thesis were performed at the Department of Cardiology of the Leiden University Medical Center, Leiden, The Netherlands
Cover: Adrianus P. Wijnmaalen
Lay-out en printing: Optima Grafische Communicatie, Rotterdam, The Netherlands ISBN: 978-94-6169-213-9
Copyright © Adrianus P. Wijnmaalen, Rotterdam, The Netherlands. All rights reserved. No part of this book may be reproduced or transmitted, in any form or by any means, without permission of the author.
Financial support for the costs associated with the publication of this thesis was received from: Boehringer Ingelheim BV, Biosense Webster, Biotronik Nederland BV, ChipSoft BV, GE Healthcare, J.E. Jurriaanse Stichting, MSD Nederland BV, Servier Nederland Farma BV, St. Jude Medical and Toshiba Medical Systems Nederland.
Substrate of Ventricular Tachycardia
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit van Leiden, op gezag van de Rector Magnificus Prof.mr. P.F. van der Heijden,
volgens het besluit van het College voor Promoties te verdedigen op donderdag 22 maart 2012
klokke 13.45 uur door
Adrianus Pieter Wijnmaalen geboren te Rotterdam
in 1980
Promotiecommissie
Promotor: Prof. Dr. M.J. Schalij Co-promotor: Dr. K. Zeppenfeld
Overige leden: Prof. Dr. R.J.M Klautz
Prof. Dr. J.M.T de Bakker (AMC, Amsterdam) Prof. Dr. G. Hindricks (University of Leipzig, Leipzig) Dr. D.A. Pijnappels
Dr. R.J. van der Geest
Financial support by the Netherlands Heart Foundation for the publication of this thesis is gratefully acknowledged.
inquietum est cor nostrum, donec requiescat in te
Augustine of Hippo
Contents
Chapter 1 Introduction and outline of the thesis
Adapted from Minerva Cardioangiol. 2011 Apr;59(2):149-69.
8
Part I Determinants of ventricular tachycardia substrate and techniques for substrate identification
41
Chapter 2 ECG identification of scar-related ventricular tachycardia with a left bundle branch block configuration
Circ Arrhythm Electrophysiol. 2011 Aug 1;4(4):486-93.
42
Chapter 3 Reversed polarity of bipolar electrograms to predict a successful ablation site in focal idiopathic right ventricular outflow tract arrhythmias
Heart Rhythm. 2011 May;8(5):665-71.
62
Chapter 4 Early reperfusion during acute myocardial infarction affects ventricular tachycardia characteristics and the chronic electroanatomical and histological substrate
Circulation. 2010 May 4;121(17):1887-95.
80
Chapter 5 Head-to-head comparison of contrast-enhanced magnetic resonance imaging and electroanatomical voltage mapping to assess post-infarct scar characteristics in patients with ventricular tachycardias: real-time image integration and reversed registration
Eur Heart J. 2011 Jan;32(1):104-14.
100
Chapter 6 Real-time integration of MDCT derived coronary anatomy and epicardial fat: Impact on electroanatomical mapping and ablation for ventricular arrhythmias
Submitted.
120
Part II Catheter ablation and outcome in different ventricular tachycardia substrates
145
Chapter 7 Beneficial effects of catheter ablation on left ventricular and right ventricular function in patients with frequent premature ventricular contractions and preserved ejectionfraction
Heart. 2010 Aug;96(16):1275-80.
146
Chapter 8 Patients with scar-related right ventricular tachycardia:
determinants of long term outcome
J Cardiovasc Electrophysiol. 2009 Oct;20(10):1119-27.
162
Chapter 9 Early reperfusion affects inducibility, cycle length and occurrence of VT
Circ Arrhythm Electrophysiol. 2011 Apr 1;4(2):195-201.
182
Chapter 10 Catheter ablation of ventricular tachycardia after left ventricular reconstructive surgery for ischemic cardiomyopathy
Heart Rhythm. 2012 Jan; 9(1):10-7
200
Summary and conclusions Samenvatting en conclusies List of publications
Dankwoord Curriculum Vitae Color section figures
219 229 239 243 247 251