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University of Groningen Self-Replication out-of-Equilibrium Yang, Shuo

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University of Groningen

Self-Replication out-of-Equilibrium Yang, Shuo

DOI:

10.33612/diss.171627402

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Yang, S. (2021). Self-Replication out-of-Equilibrium. University of Groningen. https://doi.org/10.33612/diss.171627402

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Stellingen

Behorende bij het proefschrift:

Self-Replication Out-of-Equilibrium

Shuo Yang

1. Systems chemistry provides a bridge between biology and chemistry, while aspects of diversity and dissipative states are the pillars that still need to be built.

2. Mutation during replication is the primary source of genetic diversity in biological evolution. However, in chemical evolution, prior to the appearance of self-replicating molecules, random polymerization contributes strongly to molecular diversity.

3. Life can be expressed in the form of a large number of chemical kinetic equations.

4. A sustainable (but not necessarily self-sustained) chemical system capable of Darwinian evolution can be considered as alive.

5. Darwinian evolution at the molecular level results in homochirality in biopolymers.

6. Doing a PhD is like being an evolvable replicator, starting off by replicating a previous finding, followed by altering experimental design with the goal of discovering novelty (mutation). Besides, instead of merely being a self-replicator, a PhD candidate should altruistically cross-catalyze colleagues’ work.

7. The combination of knowledge and unpredictability makes science beautiful.

8. One seemingly insignificant experimental observation could be crucial.

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