The handle
http://hdl.handle.net/1887/71027
holds various files of this Leiden University
dissertation.
Author: Buul, A.R. van
Title: Chronic obstructive pulmonary disease : new insights in morning symptons and
physical activity
Chronic obstructive pulmonary disease
New insights in morning symptoms and physical activity
Chronic obstructive pulmonary disease
New insights in morning symptoms and physical activity
Proefschrift ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op donderdag 11 april 2019
klokke 15.00 uur door
Amanda Rosanne van Buul geboren te Spijkenisse
CO-PROMOTOR:
Dr. M.J. Kasteleyn
LEDEN PROMOTIECOMMISSIE:
Prof. Dr. A.W.M. Evers
CONTENTS
Chapter 1 Introduction 9
Chapter 2 Association between morning symptoms and physical activity in COPD: a systematic review
23
Chapter 3 The association between objectively measured physical activity and morning symptoms in COPD
51
Chapter 4 Physical activity in the morning and afternoon is lower in patients with chronic obstructive pulmonary disease with morning symp-toms
73
Chapter 5 Pulmonary function and medication use are associated with
physical activity in very mild to moderate COPD: a population based study
95
Chapter 6 A systematic diagnostic evaluation combined with an internet-based self-management support system for patients with asthma or COPD
117
Chapter 7 Discussion 137
Chapter 8 Summary 157
Addendum Nederlandse samenvatting 167
List of publications 173
Curriculum vitae 175