Physiology and pathophysiology of the ileal brake in humans
Vu, M.K.
Citation
Vu, M. K. (2007, September 25). Physiology and pathophysiology of the ileal brake in humans. Department Gastroentero-hepatolgy, Medicine / Leiden University Medical Center (LUMC), Leiden University. Retrieved from https://hdl.handle.net/1887/12350
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
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STATEMENTS
1. Distal jejunal feeding might be beneficial in the acute phase of pancreatitis.
This thesis 2. Ileal brake induced satiety and proximal gastric relaxation are not
mediated through PYY as a circulating gut hormone.
This thesis 3. Medium chain triglycerides (MCT) should not be used as dietary
supplements in malabsorption states.
This thesis 4. Activation of the ileal brake with subsequent PYY release in
malabsorptive disorders is secondary, resulting from malabsorption rather than primarily, due to the underlying disease.
This thesis 5. Intestinal intubation of an ileal catheter is just a matter of being
patient.
6. Obese subjects have lower plasma PYY levels which are increased after gastric bypass surgery (le Roux et al, Endocrinology 2006, 147:3-8 and Chan et al, Obesity 2006,14:194 -98)
7. Melatonin is an inhibitory modulator of the ileal brake mechanism.
(Martin et al , Scand. J. Gastrol. 2005;40:559-63)
8. The ileal brake is the gut’s traffic light.
9. Only those who are asleep make no mistakes. (Ingvar Kamprad, founder of IKEA)
10. A Starbucks coffee shop inside the ancient walls of Beijing’s Forbidden City is one of the most incongruous sights of the globalised age. However, promoting coffee consumption in Asia could be of value sinds coffee reduces the risk of liver cirrhosis and primary liver cancer.
11. Always ask for forgiveness and never for permission.
My Vu
Leiden, September 2007
