Citation
Finken, M. J. J. (2007, November 22). Preterm birth, early growth and adult
metabolic health. Retrieved from https://hdl.handle.net/1887/12472
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral
thesis in the Institutional Repository of the University
of Leiden
Downloaded from: https://hdl.handle.net/1887/12472
Note: To cite this publication please use the final published version (if
applicable).
ADULTHOOD
HIGHER
GAIN
DOES
WEIGHT
-ARTIJN
%LYSmE
0/03
$IABETOLOGIA
0RETERM
!BSTRACT
/BJECTIVES
!N
INCLUDING
0REMATURE
NOT
SCORE
OF
WELL
-ETHODS
4HIS
FOR GESTATIONAL AGE
MEASURED
TATIC
2ESULTS
"IRTH
TERM
CIATED
WAS
#ONCLUSIONS
)N
SULIN
INSULIN
TERS
0RETERM
)NTRODUCTION
%FFECTS
PING
WITH
OF
WEIGHT
,ESS
IN
CHILDREN
4HE
YEAR OLD
WEIGHTS
THTIONS
GROWTH
GROWTH
GAIN
SUBJECTS
STUDIES
ASSOCIATIONS
THERE
AFTER
7E
COHORT
AGE
GESTATIONAL
ALSO
GAIN
-ETHODS
0OPULATION
4HE
TICENTER
WEEKS
IN
ONWARDS
DED
FREE
MULTIPLE
MOTHERS
STUDY
WELL
ALL
3TUDY
3UBJECTS
BETWEEN
OF
RISTICS
0RETERM
4ABLE 0ERINATAL
#HARACTERISTIC 0ARTICIPANTS .ON RESPONDERS 0
.
'ENERAL
-ALES
7HITES
3OCIO ECONOMIC A
/BSTETRIC
-ATERNAL
0ARITY
0ART
(YPERTENSION
3MOKING
$RUGSB
0ROLONGED
.EONATAL
'ESTATIONAL
"IRTH
7EIGHT
7EIGHT
6ALUES
$ICHOTOMOUSχ
A-ANN 7HITNEY
B3MOKING
6ENOUS
WAS
TRAINING
WHILE
SCALE
CES
MEASUREMENTS
THE
MASS
2AHAMAN
0/03
,ABORATORY
"LOOD
O#
'LUCOSE
HIGHLY
0RETERM
4ABLE #HARACTERISTICS
#HARACTERISTIC -EN 7OMEN 0
.
(EIGHT
7EIGHT
"-)
7AIST
7(2
!BSOLUTE
&AT FREE
&AT
'LUCOSE
)NSULIN
# PEPTIDE
(/-! )2
6ALUES
AND
DIFFERENT
(/-! )2
PARAMETERS
BY
3TATISTICAL
!UXOLOGICAL
CORRECT
RECENTLY
2ESULTS
VARIABLES
LOG TRANS
FORMED
0RETERM
4ABLE 2EGRESSION
PARAMETERS
/UTCOME #RUDEA !DJUSTEDB )NTERACTION
BIRTH
. 0 . 0 . 0
,OG
# PEPTIDE
,OG
A!DJUSTED
B!DJUSTED
"IRTH
MODEL
WEIGHT
METERS
INSULIN
ENTERED
RESIDUAL
FROM
WITH
WAS
MODEL
!NALYSES
THE
TIPLE
AND
WERE
3TATISTICAL
BY
COMPARED
2ESULTS
!T
AND
TRACEABLE
PREGNANT
TO
STATISTICAL
.ON RESPONSE
STATUS
HAD
&OR
MEANS
IN
GREATER
THE
0RETERM
ORAL
PARAMETERS
"IRTH
FANCY
CORRECTION
UNCHANGED
CIATED
FOR
ON
IN
SHOWN
%XCEPT
CIATED
WEIGHT
INTERACTION
BETWEEN
(/-! )2
PARAMETERS
$ISCUSSION
&ROM
AS
LEVELS
HIGHER
ADULT
TION
THAN
OF
CLEAR
)T
IS
BEEN
±CATCH UP
0RETERM
SOCIATION
STATUS
AND
0RETERM
4ABLE 2EGRESSION
OF
/UTCOME #RUDEA !DJUSTEDB )NTERACTION
. 0 . 0 . 0
,OG
# PEPTIDE
,OG
A!DJUSTED
B!DJUSTED
DIFFER
NON WHITES
JECTS
WITH
FOUND
WHITES
NOT
AMONG
PART
VARIABLES
OF
BIAS
COMPLETELY
RESISTANCE
RESISTANCE
WEIGHT
RISK
ALTHOUGH
IN
BIRTH
0RETERM
&IGURE %FFECTS
AGE
0.45
0.40
0.35
0.30
0.25
0.20
0.15
Log HOMA-IR (95% CI)
Birth weight SDS and adult
absolute fat mass
HBW-lean LBW
-lean HBW
-obese LBW
-obese
,"7
("7
("7 LEAN
ABSOLUTE ,"7 LEAN
ABSOLUTE ("7 OBESE
ABSOLUTE ,"7 OBESE
ABSOLUTE
!LTHOUGH
AFTER
LOW
MANY
IN
RESPIRATORY
4O
TYPE
WERE
UNRELATED
IN
CHILDREN
RESISTANCE
WEIGHT
GAIN
PROINSULIN
VATIONS
7E
AND
WHICH
INTERACTION
AND
RELATED
FAT
EFFECT
#ONCLUSIONS
)N
SHOWED
YEARS
AND
MULATION
WEIGHT
!
PREDICTOR
INFANCY
0RETERM
(/-! )2
RAGING
DEVELOPING
OF
INTERVENTION
2ECENTLY
AT
APPROXIMATES
M5L
SOME
TRACKING
TRICIANS
FOLLOW UP
IT
RESISTANCE
3'!
VERY
2EFERENCES
(ALES
"-*
.EWSOME INSULIN
3OTO SMALL FOR GESTATIONAL AGE -ETAB
&ORSEN PERSONS
,EVITT AMPLIFY 3OUTH
"HARGAVA IMPAIRED
(OFMAN
"AZAES SECRETION
.IKLASSON A
+NOPS PRETERM
0RETERM
3INGHAL IN
6ERLOOVE 6ANHORICK IN BIRTH WEIGHT
7ALTHER OF
&REDRIKS CUMFERENCE 0EDIATR
$URNIN OF
%USER AND FEMALES
-ATTHEWS MENT
IN
'UNGOR INSULIN
#ONWELL AND
STANDARDS
!CTA
&REDRIKS PARED
.ETHERLANDS
GROWTH
+EIJZER 6EEN REGRESSION DISEASES²
,UCAS
CULAR
(ALES THESIS
RETARDATION
HYPOTHESIS
+RAMER IS
LOW
0RETERM
OF
BIRTH
,UNDGREN BORN
WEIGHT
CHILDHOOD
0RETERM
