Nepal, Suruchi
DOI:
10.33612/diss.103413360
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from
it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date:
2019
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Nepal, S. (2019). A proteogenomic view on antibiotic resistance in pathogenic Enterobacter species.
University of Groningen. https://doi.org/10.33612/diss.103413360
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal Processed on: 13-11-2019 Processed on: 13-11-2019 Processed on: 13-11-2019
Processed on: 13-11-2019 PDF page: 1PDF page: 1PDF page: 1PDF page: 1
A proteogenomic view on antibiotic resistance in
pathogenic Enterobacter species
537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal Processed on: 13-11-2019 Processed on: 13-11-2019 Processed on: 13-11-2019
Processed on: 13-11-2019 PDF page: 2PDF page: 2PDF page: 2PDF page: 2
A proteogenomic view on antibiotic resistance in pathogenic Enterobacter species
Dissertation of the University of Groningen
ISBN: 978-94-034-2212-1 (printed book) ISBN: 978-94-034-2211-4 (electronic version)
Cover photo: Concept by Francis M Cavallo , Suruchi Nepal Printed by : Ipskamp drukkers
537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal Processed on: 13-11-2019 Processed on: 13-11-2019 Processed on: 13-11-2019
Processed on: 13-11-2019 PDF page: 3PDF page: 3PDF page: 3PDF page: 3
A proteogenomic view on antibiotic resistance in
pathogenic Enterobacter species
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the Rector Magnificus Prof. C. Wijmenga
and in accordance with the decision by the College of Deans. This thesis will be defended in public on Wednesday 27 November 2019 at 12:45 hrs
by
Suruchi Nepal
born on 17 January 1987537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal Processed on: 13-11-2019 Processed on: 13-11-2019 Processed on: 13-11-2019
Processed on: 13-11-2019 PDF page: 4PDF page: 4PDF page: 4PDF page: 4
Assessment committee
Prof. A. J. M. Driessen Prof. W. J. Quax Prof. K. Becker
537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal Processed on: 13-11-2019 Processed on: 13-11-2019 Processed on: 13-11-2019
Processed on: 13-11-2019 PDF page: 5PDF page: 5PDF page: 5PDF page: 5
Paranymphs
Francis M Cavallo Bimal Prajapati Marines du Teil Espina
537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal Processed on: 13-11-2019 Processed on: 13-11-2019 Processed on: 13-11-2019
Processed on: 13-11-2019 PDF page: 6PDF page: 6PDF page: 6PDF page: 6
cephalosporinase and carbapenemase genes in Enterobacteriaceae
Published in Virulence. 2018; 9: 1377-1389
Chapter 3 A proteogenomic ‘sneak preview’ on carbapenem resistance 62
development in the Enterobacter cloacae complex Manuscript to be submitted
Chapter 4 Multi-omics analyses of clinical isolates belonging to the 94
Enterobacter cloacae complex uncover differences in expression of determinants for antibiotic resistance and virulence
Manuscript to be submitted
Chapter 5 Antibiotic resistance plasmids cointegrated into a megaplasmid 114
harboring the bla OXA-427 carbapenemase gene
Published in Antimicrobial Agents and Chemotherapy. 2018; 62: pii: e01448-17
Chapter 6 Summarizing discussion and future perspectives 126
Chapter 7 Nederlandse samenvatting 138
Acknowledgements
537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal 537819-L-bw-Nepal Processed on: 13-11-2019 Processed on: 13-11-2019 Processed on: 13-11-2019
