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Diagnosing pulmonary embolism: establishing and consolidating the role of spiral CT Strijen, M. van

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Diagnosing pulmonary embolism: establishing and

consolidating the role of spiral CT

Strijen, M. van

Citation

Strijen, M. van. (2007, March 22). Diagnosing pulmonary embolism:

establishing and consolidating the role of spiral CT. Department of

Radiology, Leiden University Medical Center (LUMC), Faculty of Medicine, Leiden University. Retrieved from https://hdl.handle.net/1887/11452

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/11452

Note: To cite this publication please use the final published version (if applicable).

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Diagnosing pulmonary embolism:

establishing and consolidating

the role of spiral CT

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden

op gezag van de Rector Magnificus Prof. Mr. P.F. van der Heijden, volgens het besluit van het College voor Promoties

te verdedigen op donderdag 22 maart 2007 klokke 13:45

door

Marco van Strijen

geboren te Dordrecht in 1970

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Promotiecommissie

Promotoren:

Prof. dr. J.L. Bloem

Prof. dr. P.M.T. Pattynama (Erasmus Medisch Centrum, Rotterdam)

Co-promotor:

Dr. M.V. Huisman

Referent:

Prof. Dr. F.R. Rosendaal

Overige leden:

Prof. Dr. K.F.G. Rabe

Prof. Dr. W.P.T.M. Mali (Universitair Medisch Centrum Utrecht, Utrecht)

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Dankzij mijn ouders Voor Claudia

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© Marco J.L. van Strijen, Houten, The Netherlands. All rights preserved. No parts of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without prior written permission of the author.

Cover: spiral (or helical) CT is the diagnostic technique in which a rontgen tube circles around a patient in a continuous motion to acquire atttenuation information that can be used to reconstruct images. The Antelope logo was designed by the author for the Antelope study: “Advances in New Technologies Evaluating Localisation Of Pulmonary Embolism”.

Lay-out: M.J.L. van Strijen Printed by: RDS, Odijk

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Contents

Chapter 1

Introduction and outline

Chapter 2

Availability of diagnostic facilities in The Netherlands for patients with suspected pulmonary embolism.

Chapter 3

The application of a Dutch consensus diagnostic strategy for pulmonary embolism in clinical practice.

Chapter 4

Accuracy of spiral CT in the diagnosis of pulmonary embolism: a prospective multicenter cohort study of consecutive patients with abnormal perfusion scintigraphy.

Chapter 5

Diagnosis of Pulmonary Embolism with Spiral CT as a second procedure following scintigraphy.

Chapter 6

Acute Pulmonary Embolism: The effect of image quality on the accuracy of spiral CT angiography.

Chapter 7

Non-invasive diagnostic tests for pulmonary embolism: Less useful when needed the most.

Chapter 8

Single-detector Helical CT as the Primary Diagnostic Test in Suspected Pulmonary Embolism: A Multicenter Clinical Management Study in 512 Patients.

Chapter 9

Helical CT and alternative diagnosis in patients with excluded pulmonary embolism.

Chapter 10

Results of a new survey among internists and pulmonologists:

a comparison to results from 1997.

Chapter 11

Summary / Samenvatting

Curriculum Vitae

Curriculum vitae 9

17

37

53

73

89

103

115

131

149

159

179

Antelope phase IAntelope phase II

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