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University of Groningen

Insight in the brain

Larabi, Daouia

DOI:

10.33612/diss.118152005

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Larabi, D. (2020). Insight in the brain: a multimodal approach investigating insight in individuals with a psychotic disorder and healthy individuals. University of Groningen.

https://doi.org/10.33612/diss.118152005

Copyright

Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

(2)

Insight in the brain

Larabi, Daouia

DOI:

10.33612/diss.118152005

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Larabi, D. (2020). Insight in the brain: a multimodal approach investigating insight in individuals with a

psychotic disorder and healthy individuals. [Groningen]: University of Groningen.

https://doi.org/10.33612/diss.118152005

Copyright

Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).

Take-down policy

If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.

Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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INSIGHT IN THE BRAIN

A multimodal approach investigating insight in individuals

with a psychotic disorder and healthy individuals

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INSIGHT IN THE BRAIN

A multimodal approach investigating insight in individuals

with a psychotic disorder and healthy individuals

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the Rector Magnificus Prof. C. Wijmenga

and in accordance with the decision by the College of Deans. This thesis will be defended in public on Monday 7 September 2020 at 16.15 hours

by

Daouia Ismahen Larabi born on 2 April 1988

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Prof. R. Bruggeman Prof. V. Kumari

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Table of Contents

Chapter 1 General Introduction 7

Chapter 2 Systematic review and meta-analysis of neuroimaging studies on insight in psychosis

25

Chapter 3 An 1H-MRS study on prefrontal neurometabolite

concentrations and insight in psychosis

81

Chapter 4 An fMRI study on the neural correlates of emotion regulation and insight in schizophrenia

99

Chapter 5 A graph theoretical study of gray matter networks and insight in psychosis

127

Chapter 6 Temporal dynamics of resting state functional connectivity, structural connectomes and self-reflectiveness

159

Chapter 7 General discussion and future perspectives 187 References

Nederlandstalige samenvatting (Dutch summary) Short English abstract

Korte Nederlandstalige samenvatting (short Dutch abstract) Curriculum Vitae Dankwoord (acknowledgements) 209 235 241 245 249 255

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